OTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo

A putative OTU domain-containing protein 1 deubiquitinating enzyme is differentially expressed in thyroid cancer and identifies less-aggressive tumours

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Clinical significance of different types ofp53gene alteration in surgically treated prostate cancer

(2014) Martina Kluth et al.   INTERNATIONAL JOURNAL OF CANCER

Fine-Tuning of DNA Damage-Dependent Ubiquitination by OTUB2 Supports the DNA Repair Pathway Choice

(2014) Kiyoko Kato et al.   MOLECULAR CELL

Colon cancer bears overexpression of OTUB1

(2014) Xin Liu et al.   PATHOLOGY RESEARCH AND PRACTICE

Cancer statistics, 2013

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OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis

(2013) Tycho E.T. Mevissen et al.   CELL

A20-mediated negative regulation of canonical NF-κB signaling pathway

(2013) Rajeshree Pujari et al.   IMMUNOLOGIC RESEARCH

OTULIN Restricts Met1-Linked Ubiquitination to Control Innate Immune Signaling

(2013) Berthe Katrine Fiil et al.   MOLECULAR CELL

Polyamines Transduce the Nongenomic, Androgen-Induced Calcium Sensitization in Intestinal Smooth Muscle

(2013) María C. González-Montelongo et al.   MOLECULAR ENDOCRINOLOGY

E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

(2013) Reuven Wiener et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

The preventative effects of sunitinib malate observed in the course from non-castration to castration LNCaP xenograft prostate tumors

(2012) Chen Jing et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

The mechanism of OTUB1-mediated inhibition of ubiquitination

(2012) Reuven Wiener et al.   NATURE

NIH Image to ImageJ: 25 years of image analysis

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Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1

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Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains

(2011) Julien D F Licchesi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities

(2011) Rong Hu et al.   PROSTATE

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Low Levels of Phosphorylated Epidermal Growth Factor Receptor in Nonmalignant and Malignant Prostate Tissue Predict Favorable Outcome in Prostate Cancer Patients

(2010) P. Hammarsten et al.   CLINICAL CANCER RESEARCH

Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion

(2010) Mariola J. Edelmann et al.   FEBS Journal

Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

(2010) Shinichiro Nakada et al.   NATURE

Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne

(2010) Anja Bremm et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Treatment-Dependent Androgen Receptor Mutations in Prostate Cancer Exploit Multiple Mechanisms to Evade Therapy

(2009) M. P. Steinkamp et al.   CANCER RESEARCH

Increased Expression of Androgen Receptor Sensitizes Prostate Cancer Cells to Low Levels of Androgens

(2009) K. K. Waltering et al.   CANCER RESEARCH

OTU Domain-containing Ubiquitin Aldehyde-binding Protein 1 (OTUB1) Deubiquitinates Estrogen Receptor (ER) α and Affects ERα Transcriptional Activity

(2009) Vladimir Stanišić et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Breaking the chains: structure and function of the deubiquitinases

(2009) David Komander et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ezrin mediates c-Myc actions in prostate cancer cell invasion

(2009) Y-C Chuan et al.   ONCOGENE

A transcription co-factor integrates cell adhesion and motility with the p53 response

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Understanding the Epidemiology, Natural History, and Key Pathways Involved in Prostate Cancer

(2009) E. David Crawford   UROLOGY

Structural basis and specificity of human otubain 1-mediated deubiquitination

(2008) Mariola J. Edelmann et al.   BIOCHEMICAL JOURNAL

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Targeting the stromal androgen receptor in primary prostate tumors at earlier stages

(2008) Y. Niu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA