E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1

OTUB1 modulates c-IAP1 stability to regulate signalling pathways

(2013) Tatiana Goncharov et al.   EMBO JOURNAL

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function

(2012) Yu-Chi Juang et al.   MOLECULAR CELL

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

(2012) Anna Plechanovová et al.   NATURE

The mechanism of OTUB1-mediated inhibition of ubiquitination

(2012) Reuven Wiener et al.   NATURE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Ubiquitin in Motion: Structural Studies of the Ubiquitin-Conjugating Enzyme∼Ubiquitin Conjugate

(2011) Jonathan N. Pruneda et al.   BIOCHEMISTRY

Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1

(2011) Xiao-Xin Sun et al.   EMBO JOURNAL

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Mechanism of ubiquitylation by dimeric RING ligase RNF4

(2011) Anna Plechanovová et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

(2010) Shinichiro Nakada et al.   NATURE

Crystal Structure of UbcH5b∼Ubiquitin Intermediate: Insight into the Formation of the Self-Assembled E2∼Ub Conjugates

(2010) Eri Sakata et al.   STRUCTURE

Defining the Human Deubiquitinating Enzyme Interaction Landscape

(2009) Mathew E. Sowa et al.   CELL

An Inhibitor of a Deubiquitinating Enzyme Regulates Ubiquitin Homeostasis

(2009) Yoko Kimura et al.   CELL

Regulation of Virus-triggered Signaling by OTUB1- and OTUB2-mediated Deubiquitination of TRAF3 and TRAF6

(2009) Shu Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

OTU Domain-containing Ubiquitin Aldehyde-binding Protein 1 (OTUB1) Deubiquitinates Estrogen Receptor (ER) α and Affects ERα Transcriptional Activity

(2009) Vladimir Stanišić et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence for Bidentate Substrate Binding as the Basis for the K48 Linkage Specificity of Otubain 1

(2009) Tao Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

Breaking the chains: structure and function of the deubiquitinases

(2009) David Komander et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protein partners of deubiquitinating enzymes

(2008) Karen H. Ventii et al.   BIOCHEMICAL JOURNAL

Structural basis and specificity of human otubain 1-mediated deubiquitination

(2008) Mariola J. Edelmann et al.   BIOCHEMICAL JOURNAL