Activation of peroxisome proliferator-activated receptor gamma is crucial for antitumoral effects of 6-iodolactone

The role of iodine and δ-iodolactone in growth and apoptosis of malignant thyroid epithelial cells and breast cancer cells

(2014) Roland Gärtner et al.   Hormones-International Journal of Endocrinology and Metabolism

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(2014) Paloma Olvera-Caltzontzin et al.   MOLECULAR MEDICINE

6-Iodolactone, key mediator of antitumoral properties of iodine

(2014) Mario Nava-Villalba et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

SERPINA3K induces apoptosis in human colorectal cancer cells via activating the Fas/FasL/caspase-8 signaling pathway

(2013) Yachao Yao et al.   FEBS Journal

Iodine and doxorubicin, a good combination for mammary cancer treatment: antineoplastic adjuvancy, chemoresistance inhibition, and cardioprotection

(2013) Yunuen Alfaro et al.   Molecular Cancer

Peroxisome Proliferator Activated Receptor-α/Hypoxia Inducible Factor-1α Interplay Sustains Carbonic Anhydrase IX and Apoliprotein E Expression in Breast Cancer Stem Cells

(2013) Alessio Papi et al.   PLoS One

Nuclear receptors agonists exert opposing effects on the inflammation dependent survival of breast cancer stem cells

(2012) A Papi et al.   CELL DEATH AND DIFFERENTIATION

Uptake and antitumoral effects of iodine and 6-iodolactone in differentiated and undifferentiated human prostate cancer cell lines

(2012) Nuri Aranda et al.   PROSTATE

Peroxisome Proliferator-Activated Receptors: Role of Isoform Gamma in the Antineoplastic Effect of Iodine in Mammary Cancer

(2011) R. E. Nunez-Anita et al.   CURRENT CANCER DRUG TARGETS

Antineoplastic effect of iodine and iodide in dimethylbenz[a]anthracene-induced mammary tumors: association between lactoperoxidase and estrogen-adduct production

(2011) O. Soriano et al.   ENDOCRINE-RELATED CANCER

Peroxisome Proliferator-Activated Receptor-  Activation Inhibits Tumor Metastasis by Antagonizing Smad3-Mediated Epithelial-Mesenchymal Transition

(2010) A. K. Reka et al.   MOLECULAR CANCER THERAPEUTICS

Coactivators in PPAR-Regulated Gene Expression

(2010) Navin Viswakarma et al.   PPAR Research

Antiproliferative/Cytotoxic Activity of Molecular Iodine and Iodolactones in Various Human Carcinoma Cell Lines. No Interfering with EGF-signaling, but Evidence for Apoptosis

(2009) H. Rösner et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Peroxisome proliferator-activated receptor-γ activation and long-chain fatty acids alter lipogenic gene networks in bovine mammary epithelial cells to various extents

(2009) A.K.G. Kadegowda et al.   JOURNAL OF DAIRY SCIENCE

The Peroxisome Proliferator-Activated Receptor  /Retinoid X Receptor   Heterodimer Targets the Histone Modification Enzyme PR-Set7/Setd8 Gene and Regulates Adipogenesis through a Positive Feedback Loop

(2009) K.-i. Wakabayashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Antineoplastic effect of iodine in mammary cancer: participation of 6-iodolactone (6-IL) and peroxisome proliferator-activated receptors (PPAR)

(2009) Carmen Aceves et al.   Molecular Cancer

A complex between 6-iodolactone and the peroxisome proliferator-activated receptor type gamma may mediate the antineoplasic effect of iodine in mammary cancer

(2009) R.E. Nuñez-Anita et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Peroxisome proliferator-activated receptor gamma activates fas ligand gene promoter inducing apoptosis in human breast cancer cells

(2008) Daniela Bonofiglio et al.   BREAST CANCER RESEARCH AND TREATMENT

Peroxisome proliferator-activated receptor gamma overexpression and knockdown: impact on human B cell lymphoma proliferation and survival

(2008) Tatiana M. Garcia-Bates et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Signaling pathways involved in the antiproliferative effect of molecular iodine in normal and tumoral breast cells: evidence that 6-iodolactone mediates apoptotic effects

(2008) O Arroyo-Helguera et al.   ENDOCRINE-RELATED CANCER

The Role of PPARs in Cancer

(2008) Keisuke Tachibana et al.   PPAR Research