Systems biology approach to understanding post-traumatic stress disorder

A network-assisted co-clustering algorithm to discover cancer subtypes based on gene expression

(2014) Yiyi Liu et al.   BMC BIOINFORMATICS

Molecular evidence of stress-induced acute heart injury in a mouse model simulating posttraumatic stress disorder

(2014) J.-H. Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Machine learning for Big Data analytics in plants

(2014) Chuang Ma et al.   TRENDS IN PLANT SCIENCE

Core modular blood and brain biomarkers in social defeat mouse model for post traumatic stress disorder

(2013) Ruoting Yang et al.   BMC Systems Biology

Gene Expression and Methylation Signatures ofMAN2C1are Associated with PTSD

(2013) Monica Uddin et al.   DISEASE MARKERS

Endocrine Aspects of Post-traumatic Stress Disorder and Implications for Diagnosis and Treatment

(2013) Nikolaos P. Daskalakis et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Spontaneous brain activity in combat related PTSD

(2013) Xiaodan Yan et al.   NEUROSCIENCE LETTERS

Application of Machine Learning to Proteomics Data: Classification and Biomarker Identification in Postgenomics Biology

(2013) Anna Louise Swan et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Early PTSD Symptom Trajectories: Persistence, Recovery, and Response to Treatment: Results from the Jerusalem Trauma Outreach and Prevention Study (J-TOPS)

(2013) Isaac R. Galatzer-Levy et al.   PLoS One

Cluster Analysis of Clinical Data Identifies Fibromyalgia Subgroups

(2013) Elisa Docampo et al.   PLoS One

Pathway-based personalized analysis of cancer

(2013) Y. Drier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Genetic and Epigenetic Regulation of catechol-O-methyltransferase is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder

(2013) Seth Davin Norrholm et al.   Frontiers in Behavioral Neuroscience

PTSD and DNA Methylation in Select Immune Function Gene Promoter Regions: A Repeated Measures Case-Control Study of U.S. Military Service Members

(2013) Jennifer A. Rusiecki et al.   Frontiers in Psychiatry

Epigenetic Biomarkers as Predictors and Correlates of Symptom Improvement Following Psychotherapy in Combat Veterans with PTSD

(2013) Rachel Yehuda et al.   Frontiers in Psychiatry

Gray Matter Correlates of Posttraumatic Stress Disorder: A Quantitative Meta-Analysis

(2012) Simone Kühn et al.   BIOLOGICAL PSYCHIATRY

Core module biomarker identification with network exploration for breast cancer metastasis

(2012) Ruoting Yang et al.   BMC BIOINFORMATICS

Dynamics of protein noise can distinguish between alternate sources of gene-expression variability

(2012) Abhyudai Singh et al.   Molecular Systems Biology

Wisdom of crowds for robust gene network inference

(2012) Daniel Marbach et al.   NATURE METHODS

Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions

(2012) Torsten Klengel et al.   NATURE NEUROSCIENCE

Biological studies of post-traumatic stress disorder

(2012) Roger K. Pitman et al.   NATURE REVIEWS NEUROSCIENCE

Epigenetic Mechanisms in Learned Fear: Implications for PTSD

(2012) Iva B Zovkic et al.   NEUROPSYCHOPHARMACOLOGY

Neurocircuitry models of posttraumatic stress disorder and beyond: A meta-analysis of functional neuroimaging studies

(2012) Ronak Patel et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Molecular Variation at the SLC6A3 Locus Predicts Lifetime Risk of PTSD in the Detroit Neighborhood Health Study

(2012) Shun-Chiao Chang et al.   PLoS One

DNA methylation in repetitive elements and post-traumatic stress disorder: a case–control study of US military service members

(2012) Jennifer A Rusiecki et al.   Epigenomics

microRNA Regulatory Network Inference Identifies miR-34a as a Novel Regulator of TGF-β Signaling in Glioblastoma

(2012) Giannicola Genovese et al.   Cancer Discovery

Modeling Cortisol Dynamics in the Neuro-endocrine Axis Distinguishes Normal, Depression, and Post-traumatic Stress Disorder (PTSD) in Humans

(2012) K. Sriram et al.   PLoS Computational Biology

Differential immune system DNA methylation and cytokine regulation in post-traumatic stress disorder

(2011) Alicia K. Smith et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Exaggerated Activation of Dorsal Anterior Cingulate Cortex During Cognitive Interference: A Monozygotic Twin Study of Posttraumatic Stress Disorder

(2011) Lisa M. Shin et al.   AMERICAN JOURNAL OF PSYCHIATRY

Independent surrogate variable analysis to deconvolve confounding factors in large-scale microarray profiling studies

(2011) Andrew E. Teschendorff et al.   BIOINFORMATICS

Inferring gene regulatory networks from gene expression data by path consistency algorithm based on conditional mutual information

(2011) Xiujun Zhang et al.   BIOINFORMATICS

Glucocorticoid Receptor Pathway Components Predict Posttraumatic Stress Disorder Symptom Development: A Prospective Study

(2011) Mirjam van Zuiden et al.   BIOLOGICAL PSYCHIATRY

SLC6A4 methylation modifies the effect of the number of traumatic events on risk for posttraumatic stress disorder

(2011) Karestan C. Koenen et al.   DEPRESSION AND ANXIETY

Non-fatal cardiovascular outcome in patients with posttraumatic stress symptoms caused by myocardial infarction

(2011) Roland von Känel et al.   Journal of Cardiology

Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor

(2011) Kerry J. Ressler et al.   NATURE

Neuronal activity modifies the DNA methylation landscape in the adult brain

(2011) Junjie U Guo et al.   NATURE NEUROSCIENCE

Animal model for PTSD: From clinical concept to translational research

(2011) Hagit Cohen et al.   NEUROPHARMACOLOGY

Biomarkers of PTSD: Neuropeptides and immune signaling

(2011) Dewleen G. Baker et al.   NEUROPHARMACOLOGY

PTSD and gene variants: New pathways and new thinking

(2011) Kelly Skelton et al.   NEUROPHARMACOLOGY

Removing Batch Effects in Analysis of Expression Microarray Data: An Evaluation of Six Batch Adjustment Methods

(2011) Chao Chen et al.   PLoS One

Decreased regional cerebral blood flow in medial prefrontal cortex during trauma-unrelated stressful imagery in Vietnam veterans with post-traumatic stress disorder

(2011) A. L. Gold et al.   PSYCHOLOGICAL MEDICINE

Altered Amygdala Resting-State Functional Connectivity in Post-Traumatic Stress Disorder

(2011) Christine A. Rabinak et al.   Frontiers in Psychiatry

A Decade of Systems Biology

(2010) Han-Yu Chuang et al.   Annual Review of Cell and Developmental Biology

Magnetic Resonance Imaging of Hippocampal Subfields in Posttraumatic Stress Disorder

(2010) Zhen Wang et al.   ARCHIVES OF GENERAL PSYCHIATRY

Neural Correlates of Altered Pain Response in Women with Posttraumatic Stress Disorder from Intimate Partner Violence

(2010) Irina A. Strigo et al.   BIOLOGICAL PSYCHIATRY

Exaggerated and Disconnected Insular-Amygdalar Blood Oxygenation Level-Dependent Response to Threat-Related Emotional Faces in Women with Intimate-Partner Violence Posttraumatic Stress Disorder

(2010) Gregory A. Fonzo et al.   BIOLOGICAL PSYCHIATRY

Suppressed monocyte gene expression profile in men versus women with PTSD

(2010) Thomas C. Neylan et al.   BRAIN BEHAVIOR AND IMMUNITY

Altered Processing of Contextual Information during Fear Extinction in PTSD: An fMRI Study

(2010) Ansgar Rougemont-Bücking et al.   CNS Neuroscience & Therapeutics

The minimal model of the hypothalamic–pituitary–adrenal axis

(2010) Frank Vinther et al.   JOURNAL OF MATHEMATICAL BIOLOGY

Fundamental limits on the suppression of molecular fluctuations

(2010) Ioannis Lestas et al.   NATURE

Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons

(2010) Jian Feng et al.   NATURE NEUROSCIENCE

Tackling the widespread and critical impact of batch effects in high-throughput data

(2010) Jeffrey T. Leek et al.   NATURE REVIEWS GENETICS

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

Epigenetic and immune function profiles associated with posttraumatic stress disorder

(2010) M. Uddin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Revealing strengths and weaknesses of methods for gene network inference

(2010) D. Marbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sex Differences in Heart Rate Responses to Script-Driven Imagery Soon After Trauma and Risk of Posttraumatic Stress Disorder

(2010) Birgit Kleim et al.   PSYCHOSOMATIC MEDICINE

Emotional processing in anterior cingulate and medial prefrontal cortex

(2010) Amit Etkin et al.   TRENDS IN COGNITIVE SCIENCES

Trends and Risk Factors for Mental Health Diagnoses Among Iraq and Afghanistan Veterans Using Department of Veterans Affairs Health Care, 2002–2008

(2009) Karen H. Seal et al.   AMERICAN JOURNAL OF PUBLIC HEALTH

Resting Metabolic Activity in the Cingulate Cortex and Vulnerability to Posttraumatic Stress Disorder

(2009) Lisa M. Shin et al.   ARCHIVES OF GENERAL PSYCHIATRY

Gene Expression Patterns Associated with Posttraumatic Stress Disorder Following Exposure to the World Trade Center Attacks

(2009) Rachel Yehuda et al.   BIOLOGICAL PSYCHIATRY

Neurobiological Basis of Failure to Recall Extinction Memory in Posttraumatic Stress Disorder

(2009) Mohammed R. Milad et al.   BIOLOGICAL PSYCHIATRY

Single prolonged stress: toward an animal model of posttraumatic stress disorder

(2009) Shigeto Yamamoto et al.   DEPRESSION AND ANXIETY

A chance at survival: gene expression noise and phenotypic diversification strategies

(2009) Dawn Fraser et al.   MOLECULAR MICROBIOLOGY

The Neurocircuitry of Fear, Stress and Anxiety Disorders

(2009) Lisa M Shin et al.   NEUROPSYCHOPHARMACOLOGY

Alterations in the neural circuitry for emotion and attention associated with posttraumatic stress symptomatology

(2009) Jasmeet Pannu Hayes et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Self-Control in Decision-Making Involves Modulation of the vmPFC Valuation System

(2009) T. A. Hare et al.   SCIENCE

Functional Activation and Neural Networks in Women with Posttraumatic Stress Disorder Related to Intimate Partner Violence

(2008) Alan N. Simmons et al.   BIOLOGICAL PSYCHIATRY

Current status of brain imaging in anxiety disorders

(2008) Cristian Damsa et al.   CURRENT OPINION IN PSYCHIATRY

Association of FKBP5 Polymorphisms and Childhood Abuse With Risk of Posttraumatic Stress Disorder Symptoms in Adults

(2008) Elisabeth B. Binder   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A Biologically Realistic Network Model of Acquisition and Extinction of Conditioned Fear Associations in Lateral Amygdala Neurons

(2008) Guoshi Li et al.   JOURNAL OF NEUROPHYSIOLOGY

Epigenetic Regulation of bdnf Gene Transcription in the Consolidation of Fear Memory

(2008) F. D. Lubin et al.   JOURNAL OF NEUROSCIENCE

Inferring Pathway Activity toward Precise Disease Classification

(2008) Eunjung Lee et al.   PLoS Computational Biology

Evidence for Acquired Pregenual Anterior Cingulate Gray Matter Loss from a Twin Study of Combat-Related Posttraumatic Stress Disorder

(2007) Kiyoto Kasai et al.   BIOLOGICAL PSYCHIATRY