Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin and G proteins

GIV/Girdin Transmits Signals from Multiple Receptors by Triggering Trimeric G Protein Activation

(2015) Mikel Garcia-Marcos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multimodular biosensors reveal a novel platform for activation of G proteins by growth factor receptors

(2015) Krishna K. Midde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serpins Promote Cancer Cell Survival and Vascular Co-Option in Brain Metastasis

(2014) Manuel Valiente et al.   CELL

GIV/Girdin Links Vascular Endothelial Growth Factor Signaling to Akt Survival Signaling in Podocytes Independent of Nephrin

(2014) H. Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin

(2014) Changsheng Lin et al.   MOLECULAR BIOLOGY OF THE CELL

GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis

(2014) Inmaculada Lopez-Sanchez et al.   Nature Communications

The Akt substrate Girdin is a regulator of insulin signaling in myoblast cells

(2013) Angelika Hartung et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Protein kinase C-theta (PKC ) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin

(2013) I. Lopez-Sanchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FAK and talin: Who is taking whom to the integrin engagement party?: Figure 1.

(2012) Bryan Serrels et al.   JOURNAL OF CELL BIOLOGY

Immunolabeling artifacts and the need for live-cell imaging

(2012) Ulrike Schnell et al.   NATURE METHODS

Heterotrimeric G proteins, focal adhesion kinase, and endothelial barrier function

(2011) Tracy Thennes et al.   MICROVASCULAR RESEARCH

GIV/Girdin is a rheostat that fine-tunes growth factor signals during tumor progression

(2011) Pradipta Ghosh et al.   Cell Adhesion & Migration

A Structural Determinant That Renders GαiSensitive to Activation by GIV/Girdin Is Required to Promote Cell Migration

(2010) Mikel Garcia-Marcos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Gαi–GIV Molecular Complex Binds Epidermal Growth Factor Receptor and Determines Whether Cells Migrate or Proliferate

(2010) Pradipta Ghosh et al.   MOLECULAR BIOLOGY OF THE CELL

G Protein Subunit G 13 Binds to Integrin  IIb 3 and Mediates Integrin "Outside-In" Signaling

(2010) H. Gong et al.   SCIENCE

WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis

(2009) Don X. Nguyen et al.   CELL

Mechanisms that regulate adaptor binding to  -integrin cytoplasmic tails

(2009) K. R. Legate et al.   JOURNAL OF CELL SCIENCE

GIV is a nonreceptor GEF for G i with a unique motif that regulates Akt signaling

(2009) M. Garcia-Marcos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of Gαi3 triggers cell migration via regulation of GIV

(2008) Pradipta Ghosh et al.   JOURNAL OF CELL BIOLOGY