Tumor necrosis factor–related apoptosis-inducing ligand induces the expression of proinflammatory cytokines in macrophages and re-educates tumor-associated macrophages to an antitumor phenotype

Macrophages and Therapeutic Resistance in Cancer

(2015) Brian Ruffell et al.   CANCER CELL

CSF1 Receptor Targeting in Prostate Cancer Reverses Macrophage-Mediated Resistance to Androgen Blockade Therapy

(2015) J. Escamilla et al.   CANCER RESEARCH

The interaction of anticancer therapies with tumor-associated macrophages

(2015) Alberto Mantovani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epigenetic regulation of canonical TNFα pathway by HDAC1 determines survival of cardiac myocytes

(2013) Hongying Gang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

TRAIL-induced miR-146a expression suppresses CXCR4-mediated human breast cancer migration

(2013) Dongsheng Wang et al.   FEBS Journal

MicroRNAs: Essential players in the regulation of inflammation

(2013) Ana Rebane et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Histone Deacetylase 7 Promotes Toll-like Receptor 4-dependent Proinflammatory Gene Expression in Macrophages

(2013) Melanie R. Shakespear et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone deacetylase inhibitors increase microRNA-146a expression and enhance negative regulation of interleukin-1β signaling in osteoarthritis fibroblast-like synoviocytes

(2013) J.H. Wang et al.   OSTEOARTHRITIS AND CARTILAGE

Histone Deacetylases and NF-kB Signaling Coordinate Expression of CX3CL1 in Epithelial Cells in Response to Microbial Challenge by Suppressing miR-424 and miR-503

(2013) Rui Zhou et al.   PLoS One

Lysine-specific demethylase 1 (LSD1) and histone deacetylase 1 (HDAC1) synergistically repress proinflammatory cytokines and classical complement pathway components

(2012) Andreas Janzer et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TRAIL suppresses tumor growth in mice by inducing tumor-infiltrating CD4+CD25+ Treg apoptosis

(2012) Zhijuan Diao et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

CXCL1/GROα increases cell migration and invasion of prostate cancer by decreasing fibulin-1 expression through NF-κB/HDAC1 epigenetic regulation

(2012) Po-Lin Kuo et al.   CARCINOGENESIS

Macrophages, Inflammation, and Tumor Suppressors: ARF, a New Player in the Game

(2012) Paqui G. Través et al.   MEDIATORS OF INFLAMMATION

Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages

(2012) X. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulated expression of miR-146a contributes to age-related dysfunction of macrophages

(2011) Minghong Jiang et al.   AGING CELL

HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PlGF

(2011) Charlotte Rolny et al.   CANCER CELL

Myc represses miR-15a/miR-16-1 expression through recruitment of HDAC3 in mantle cell and other non-Hodgkin B-cell lymphomas

(2011) X Zhang et al.   ONCOGENE

CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans

(2011) G. L. Beatty et al.   SCIENCE

Histone deacetylases as regulators of inflammation and immunity

(2011) Melanie R. Shakespear et al.   TRENDS IN IMMUNOLOGY

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Phase I Dose-Escalation Study of Recombinant Human Apo2L/TRAIL, a Dual Proapoptotic Receptor Agonist, in Patients With Advanced Cancer

(2010) Roy S. Herbst et al.   JOURNAL OF CLINICAL ONCOLOGY

The NF-κB p50:p50:HDAC-1 repressor complex orchestrates transcriptional inhibition of multiple pro-inflammatory genes

(2010) Ahmed M. Elsharkawy et al.   JOURNAL OF HEPATOLOGY

Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll-like receptor 4 agonist LPS

(2010) Maria A. Halili et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Blood Monocytes: Development, Heterogeneity, and Relationship with Dendritic Cells

(2009) Cedric Auffray et al.   Annual Review of Immunology

TRAIL receptor mediates inflammatory cytokine release in an NF-κB-dependent manner

(2009) Wanhu Tang et al.   CELL RESEARCH

Interferon-γ reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages

(2009) Dorothée Duluc et al.   INTERNATIONAL JOURNAL OF CANCER

Differential expression of the TRAIL/TRAIL-receptor system in patients with inflammatory bowel disease

(2009) Sylvia Brost et al.   PATHOLOGY RESEARCH AND PRACTICE

Role ofmiRNA-146ain the regulation of the innate immune response and cancer

(2008) Andrew E. Williams et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Low Levels of Tumor Necrosis Factor   Increase Tumor Growth by Inducing an Endothelial Phenotype of Monocytes Recruited to the Tumor Site

(2008) B. Li et al.   CANCER RESEARCH

The inflammatory micro-environment in tumor progression: The role of tumor-associated macrophages

(2008) Paola Allavena et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced chemokine release in both TRAIL-resistant and TRAIL-sensitive cells via nuclear factor kappa B

(2008) Wanhu Tang et al.   FEBS Journal

An NF-κB-sensitive Micro RNA-146a-mediated Inflammatory Circuit in Alzheimer Disease and in Stressed Human Brain Cells

(2008) Walter J. Lukiw et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNAs: Novel Regulators During the Immune Response

(2008) Yujing Bi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A pervasive role of histone acetyltransferases and deacetylases in an NF-κB-signaling code

(2008) Miriam Calao et al.   TRENDS IN BIOCHEMICAL SCIENCES