Multiple Resistance at No Cost: Rifampicin and Streptomycin a Dangerous Liaison in the Spread of Antibiotic Resistance

Topological features of rugged fitness landscapes in sequence space

(2015) Dmitry A. Kondrashov et al.   TRENDS IN GENETICS

The rule of declining adaptability in microbial evolution experiments

(2015) Alejandro Couce et al.   Frontiers in Genetics

A SHIFT FROM MAGNITUDE TO SIGN EPISTASIS DURING ADAPTIVE EVOLUTION OF A BACTERIAL SOCIAL TRAIT

(2014) Peter C. Zee et al.   EVOLUTION

Costs of antibiotic resistance - separating trait effects and selective effects

(2014) Alex R. Hall et al.   Evolutionary Applications

Empirical fitness landscapes and the predictability of evolution

(2014) J. Arjan G.M. de Visser et al.   NATURE REVIEWS GENETICS

Microbiological effects of sublethal levels of antibiotics

(2014) Dan I. Andersson et al.   NATURE REVIEWS MICROBIOLOGY

Global epistasis makes adaptation predictable despite sequence-level stochasticity

(2014) S. Kryazhimskiy et al.   SCIENCE

Evolution of Escherichia coli rifampicin resistance in an antibiotic-free environment during thermal stress

(2013) Alejandra Rodríguez-Verdugo et al.   BMC EVOLUTIONARY BIOLOGY

RATES OF FITNESS DECLINE AND REBOUND SUGGEST PERVASIVE EPISTASIS

(2013) L. Perfeito et al.   EVOLUTION

Patterns of Epistasis between Beneficial Mutations in an Antibiotic Resistance Gene

(2013) Martijn F. Schenk et al.   MOLECULAR BIOLOGY AND EVOLUTION

The Environment Affects Epistatic Interactions to Alter the Topology of an Empirical Fitness Landscape

(2013) Kenneth M. Flynn et al.   PLoS Genetics

Increased Survival of Antibiotic-Resistant Escherichia coli inside Macrophages

(2012) Migla Miskinyte et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Epistasis between mutations is host-dependent for an RNA virus

(2012) J. Lalic et al.   Biology Letters

ANTIBIOTIC RESISTANCE AND STRESS IN THE LIGHT OF FISHER'S MODEL

(2012) Sandra Trindade et al.   EVOLUTION

The Molecular Diversity of Adaptive Convergence

(2012) O. Tenaillon et al.   SCIENCE

The heterogeneous evolution of multidrug-resistant Mycobacterium tuberculosis

(2012) Borna Müller et al.   TRENDS IN GENETICS

Strain diversity, epistasis and the evolution of drug resistance in Mycobacterium tuberculosis

(2011) S. Borrell et al.   CLINICAL MICROBIOLOGY AND INFECTION

Cost of Antibiotic Resistance and the Geometry of Adaptation

(2011) Ana Sousa et al.   MOLECULAR BIOLOGY AND EVOLUTION

The causes of epistasis

(2011) J. A. G. M. de Visser et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Negative Epistasis Between Beneficial Mutations in an Evolving Bacterial Population

(2011) A. I. Khan et al.   SCIENCE

Initial Mutations Direct Alternative Pathways of Protein Evolution

(2011) Merijn L. M. Salverda et al.   PLoS Genetics

Pervasive Sign Epistasis between Conjugative Plasmids and Drug-Resistance Chromosomal Mutations

(2011) Rui F. Silva et al.   PLoS Genetics

Diminishing Returns From Beneficial Mutations and Pervasive Epistasis Shape the Fitness Landscape for Rifampicin Resistance in Pseudomonas aeruginosa

(2010) R. C. MacLean et al.   GENETICS

The population genetics of antibiotic resistance: integrating molecular mechanisms and treatment contexts

(2010) R. Craig MacLean et al.   NATURE REVIEWS GENETICS

The cost of multiple drug resistance inPseudomonas aeruginosa

(2009) H. WARD et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

The Distribution of Fitness Effects of Beneficial Mutations in Pseudomonas aeruginosa

(2009) R. Craig MacLean et al.   PLoS Genetics

Positive Epistasis Drives the Acquisition of Multidrug Resistance

(2009) Sandra Trindade et al.   PLoS Genetics

Epistasis — the essential role of gene interactions in the structure and evolution of genetic systems

(2008) Patrick C. Phillips   NATURE REVIEWS GENETICS