Effects of ageing on expression of the muscle-specific E3 ubiquitin ligases and Akt-dependent regulation of Foxo transcription factors in skeletal muscle

Regrowth after skeletal muscle atrophy is impaired in aged rats, despite similar responses in signaling pathways

(2015) Jena R. White et al.   EXPERIMENTAL GERONTOLOGY

Muscle stem cells contribute to myofibres in sedentary adult mice

(2015) Alexandra C. Keefe et al.   Nature Communications

SMAD3 augments FoxO3-induced MuRF-1 promoter activity in a DNA-binding-dependent manner

(2014) Lance M. Bollinger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Skeletal muscle atrophy and the E3 ubiquitin ligases MuRF1 and MAFbx/atrogin-1

(2014) Sue C. Bodine et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice

(2014) Mitchell Barns et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Muscle hypertrophy is associated with increases in proteasome activity that is independent of MuRF1 and MAFbx expression

(2014) Leslie M. Baehr et al.   Frontiers in Physiology

Ageing has no effect on the regulation of the ubiquitin proteasome-related genes and proteins following resistance exercise

(2014) Renae J. Stefanetti et al.   Frontiers in Physiology

Maintenance of muscle mass and load-induced growth in Muscle RING Finger 1 null mice with age

(2013) Darren T. Hwee et al.   AGING CELL

Signalling pathways regulating muscle mass in ageing skeletal muscle. The role of the IGF1-Akt-mTOR-FoxO pathway

(2013) M. Sandri et al.   BIOGERONTOLOGY

Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome

(2013) Marco Sandri   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Heightened muscle inflammation susceptibility may impair regenerative capacity in aging humans

(2013) Edward K. Merritt et al.   JOURNAL OF APPLIED PHYSIOLOGY

FOXOs: signalling integrators for homeostasis maintenance

(2013) Astrid Eijkelenboom et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of nicotinic acetylcholine receptor turnover by MuRF1 connects muscle activity to endo/lysosomal and atrophy pathways

(2012) Rüdiger Rudolf et al.   AGE

Identification of atrogin-1-targeted proteins during the myostatin-induced skeletal muscle wasting

(2012) Sudarsanareddy Lokireddy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Stress-induced Skeletal Muscle Gadd45a Expression Reprograms Myonuclei and Causes Muscle Atrophy

(2012) Scott M. Ebert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Beta-hydroxy-beta-methyl-butyrate blunts negative age-related changes in body composition, functionality and myofiber dimensions in rats

(2012) Jacob M Wilson et al.   Journal of the International Society of Sports Nutrition

Skeletal Muscle Autophagy and Protein Breakdown Following Resistance Exercise are Similar in Younger and Older Adults

(2012) C. S. Fry et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Genomic and Proteomic Profiling Reveals Reduced Mitochondrial Function and Disruption of the Neuromuscular Junction Driving Rat Sarcopenia

(2012) C. Ibebunjo et al.   MOLECULAR AND CELLULAR BIOLOGY

Sarcopenia, Dynapenia, and the Impact of Advancing Age on Human Skeletal Muscle Size and Strength; a Quantitative Review

(2012) W. Kyle Mitchell et al.   Frontiers in Physiology

Crosstalk between Glucocorticoid Receptor and Nutritional Sensor mTOR in Skeletal Muscle

(2011) Noriaki Shimizu et al.   Cell Metabolism

Blunting of adaptive responses to resistance exercise training in women over 75y

(2011) C.A. Greig et al.   EXPERIMENTAL GERONTOLOGY

Muscle actin is polyubiquitinylated in vitro and in vivo and targeted for breakdown by the E3 ligase MuRF1

(2011) Cécile Polge et al.   FASEB JOURNAL

The role and regulation of MAFbx/atrogin-1 and MuRF1 in skeletal muscle atrophy

(2011) Victoria C. Foletta et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Applications of post-translational modifications of FoxO family proteins in biological functions

(2011) Ying Zhao et al.   Journal of Molecular Cell Biology

Myogenin and Class II HDACs Control Neurogenic Muscle Atrophy by Inducing E3 Ubiquitin Ligases

(2010) Viviana Moresi et al.   CELL

Age-associated alterations of the neuromuscular junction

(2010) Youngmok C. Jang et al.   EXPERIMENTAL GERONTOLOGY

Muscle Wasting in Aged, Sarcopenic Rats Is Associated with Enhanced Activity of the Ubiquitin Proteasome Pathway

(2010) Mikael Altun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Resistance Exercise, Skeletal Muscle FOXO3A, and 85-Year-Old Women

(2010) D. L. Williamson et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Effects of aging and gender on muscle mass and regulation of Akt-mTOR-p70s6k related signaling in the F344BN rat model

(2010) Satyanarayana Paturi et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise

(2009) Stephanie Eva Wohlgemuth et al.   EXPERIMENTAL GERONTOLOGY

Identification of MAFbx as a myogenin-engaged F-box protein in SCF ubiquitin ligase

(2009) Misako Jogo et al.   FEBS LETTERS

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

(2009) Shenhav Cohen et al.   JOURNAL OF CELL BIOLOGY

NDRG2, a novel regulator of myoblast proliferation, is regulated by anabolic and catabolic factors

(2009) Victoria C. Foletta et al.   JOURNAL OF PHYSIOLOGY-LONDON

Aging-Associated Dysfunction of Akt/Protein Kinase B: S-Nitrosylation and Acetaminophen Intervention

(2009) Miaozong Wu et al.   PLoS One

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The initiation factor eIF3-f is a major target for Atrogin1/MAFbx function in skeletal muscle atrophy

(2008) Julie Lagirand-Cantaloube et al.   EMBO JOURNAL

Human Sarcopenia Reveals an Increase in SOCS-3 and Myostatin and a Reduced Efficiency of Akt Phosphorylation

(2008) Bertrand Léger et al.   REJUVENATION RESEARCH