The metastasis-inducing protein AGR2 is O-glycosylated upon secretion from mammary epithelial cells

New Blocking Antibodies against Novel AGR2-C4.4A Pathway Reduce Growth and Metastasis of Pancreatic Tumors and Increase Survival in Mice

(2015) T. Arumugam et al.   MOLECULAR CANCER THERAPEUTICS

OsteopontinO-glycosylation contributes to its phosphorylation and cell-adhesion properties

(2014) Yoshinobu Kariya et al.   BIOCHEMICAL JOURNAL

Progressive quality control of secretory proteins in the early secretory compartment by ERp44

(2014) S. Sannino et al.   JOURNAL OF CELL SCIENCE

Engineering a synthetic cell panel to identify signalling components reprogrammed by the cell growth regulator anterior gradient-2

(2014) Terry A. Gray et al.   Molecular BioSystems

Anterior gradient protein 2 promotes survival, migration and invasion of papillary thyroid carcinoma cells

(2014) Gennaro Di Maro et al.   Molecular Cancer

N,N′-Dinitrosopiperazine-Mediated AGR2 Is Involved in Metastasis of Nasopharyngeal Carcinoma

(2014) Yuejin Li et al.   PLoS One

Pancreatic Cancer Cell Glycosylation Regulates Cell Adhesion and Invasion through the Modulation of α2β1 Integrin and E-Cadherin Function

(2014) Sònia Bassagañas et al.   PLoS One

AGR2, an Endoplasmic Reticulum Protein, Is Secreted into the Gastrointestinal Mucus

(2014) Joakim H. Bergström et al.   PLoS One

AGR2 Expression is Regulated by HIF-1 and Contributes to Growth and Angiogenesis of Glioblastoma

(2013) Xing-Yu Hong et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology

(2013) Catharina Steentoft et al.   EMBO JOURNAL

Anterior gradient 2and3- two prototype androgen-responsive genes transcriptionally upregulated by androgens and by oestrogens in prostate cancer cells

(2013) Huajie Bu et al.   FEBS Journal

Effect of dexamethasone on expression of AGR2 protein in asthmatic mice

(2013) Min Zhou et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

A Highly Sensitive Targeted Mass Spectrometric Assay for Quantification of AGR2 Protein in Human Urine and Serum

(2013) Tujin Shi et al.   JOURNAL OF PROTEOME RESEARCH

Anterior Gradient 2 and Mucin 4 Expression Mirrors Tumor Cell Differentiation in Pancreatic Adenocarcinomas, But Aberrant Anterior Gradient 2 Expression Predicts Worse Patient Outcome in Poorly Differentiated Tumors

(2013) Veronika Brychtova et al.   PANCREAS

AGR2 Is Induced in Asthma and Promotes Allergen-Induced Mucin Overproduction

(2012) Bradley W. Schroeder et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Dimerization of pro-oncogenic protein Anterior Gradient 2 is required for the interaction with BiP/GRP78

(2012) Joohyun Ryu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The estrogen-responsive Agr2 gene regulates mammary epithelial proliferation and facilitates lobuloalveolar development

(2012) Suman Verma et al.   DEVELOPMENTAL BIOLOGY

CD147 and AGR2 expression promote cellular proliferation and metastasis of head and neck squamous cell carcinoma

(2012) Larissa Sweeny et al.   EXPERIMENTAL CELL RESEARCH

Loss of Anterior Gradient 2 (Agr2) Expression Results in Hyperplasia and Defective Lineage Maturation in the Murine Stomach

(2012) Aparna Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metastasis-Promoting Anterior Gradient 2 Protein Has a Dimeric Thioredoxin Fold Structure and a Role in Cell Adhesion

(2012) Pryank Patel et al.   JOURNAL OF MOLECULAR BIOLOGY

An accurate and rapid detection of lymph node metastasis in non-small cell lung cancer patients based on one-step nucleic acid amplification assay

(2012) Masayoshi Inoue et al.   LUNG CANCER

Proteomic study explores AGR2 as pro-metastatic protein in HCC

(2012) Hongxiu Yu et al.   Molecular BioSystems

AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia

(2012) A M Norris et al.   ONCOGENE

Secondary Structure, a Missing Component of Sequence-Based Minimotif Definitions

(2012) David P. Sargeant et al.   PLoS One

Anterior gradient protein 2 (AGR2) is an independent prognostic factor in ovarian high-grade serous carcinoma

(2012) S. Darb-Esfahani et al.   VIRCHOWS ARCHIV

AGR2 Is a Novel Surface Antigen That Promotes the Dissemination of Pancreatic Cancer Cells through Regulation of Cathepsins B and D

(2011) L. Dumartin et al.   CANCER RESEARCH

AGR2, a mucinous ovarian cancer marker, promotes cell proliferation and migration

(2011) Kyoungsook Park et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Role of Pro-oncogenic Protein Disulfide Isomerase (PDI) Family Member Anterior Gradient 2 (AGR2) in the Control of Endoplasmic Reticulum Homeostasis

(2011) Arisa Higa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AGR2Gene Function Requires a Unique Endoplasmic Reticulum Localization Motif

(2011) Aparna Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential expression of the anterior gradient protein-2 is a conserved feature during morphogenesis and carcinogenesis of the biliary tree

(2011) Sébastien Lepreux et al.   LIVER INTERNATIONAL

Development of an ELISA to detect the secreted prostate cancer biomarker AGR2 in voided urine

(2011) Elizabeth A. Wayner et al.   PROSTATE

ErbB3 Binding Protein 1 Represses Metastasis-Promoting Gene Anterior Gradient Protein 2 in Prostate Cancer

(2010) Y. Zhang et al.   CANCER RESEARCH

Increased plasma concentrations of anterior gradient 2 protein are positively associated with ovarian cancer

(2010) Tracey A. Edgell et al.   CLINICAL SCIENCE

Cell Surface Relocalization of the Endoplasmic Reticulum Chaperone and Unfolded Protein Response Regulator GRP78/BiP

(2010) Yi Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elevated level of anterior gradient-2 in pancreatic juice from patients with pre-malignant pancreatic neoplasia

(2010) Ru Chen et al.   Molecular Cancer

The Metastasis-Associated Anterior Gradient 2 Protein Is Correlated with Poor Survival of Breast Cancer Patients

(2009) Dong L. Barraclough et al.   AMERICAN JOURNAL OF PATHOLOGY

Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2−/− mice

(2009) Fang Zhao et al.   DEVELOPMENTAL BIOLOGY

Proteomic Analyses of the Two Mucus Layers of the Colon Barrier Reveal That Their Main Component, the Muc2 Mucin, Is Strongly Bound to the Fcgbp Protein

(2009) Malin E. V. Johansson et al.   JOURNAL OF PROTEOME RESEARCH

Solution Structure and Phylogenetics of Prod1, a Member of the Three-Finger Protein Superfamily Implicated in Salamander Limb Regeneration

(2009) Acely Garza-Garcia et al.   PLoS One

The protein disulfide isomerase AGR2 is essential for production of intestinal mucus

(2009) S.-W. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anterior Gradient 2 Is Expressed and Secreted during the Development of Pancreatic Cancer and Promotes Cancer Cell Survival

(2008) V. Ramachandran et al.   CANCER RESEARCH

Novel endo- -N-acetylgalactosaminidases with broader substrate specificity

(2008) D. Koutsioulis et al.   GLYCOBIOLOGY

A new tumor-specific variant of GRP78 as target for antibody-based therapy

(2008) Nicole Rauschert et al.   LABORATORY INVESTIGATION

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA