Kaempferol induces autophagy through AMPK and AKT signaling molecules and causes G2/M arrest via downregulation of CDK1/cyclin B in SK-HEP-1 human hepatic cancer cells

Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions

(2012) Sung Min Son et al.   Autophagy

Ceramide stress in survival versus lethal autophagy paradox

(2012) Wenhui Jiang et al.   Autophagy

Maturing reticulocytes internalize plasma membrane in glycophorin A-containing vesicles that fuse with autophagosomes before exocytosis

(2012) R. E. Griffiths et al.   BLOOD

Hepatitis B virus X protein promotes hepatoma cell invasion and metastasis by stabilizing Snail protein

(2012) Haiou Liu et al.   CANCER SCIENCE

Activations of Both Extrinsic and Intrinsic Pathways in HCT 116 Human Colorectal Cancer Cells Contribute to Apoptosis through p53-Mediated ATM/Fas Signaling byEmilia sonchifoliaExtract, a Folklore Medicinal Plant

(2012) Yu-Hsuan Lan et al.   Evidence-based Complementary and Alternative Medicine

The Intriguing Life of Autophagosomes

(2012) Dalibor Mijaljica et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bufalin increases sensitivity to AKT/mTOR-induced autophagic cell death in SK-HEP-1 human hepatocellular carcinoma cells

(2012) SHIH-CHANG TSAI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

ERK-modulated intrinsic signaling and G2/M phase arrest contribute to the induction of apoptotic death by allyl isothiocyanate in MDA-MB-468 human breast adenocarcinoma cells

(2012) SHIH-CHANG TSAI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Dynamic and transient interactions of Atg9 with autophagosomes, but not membrane integration, are required for autophagy

(2012) A. Orsi et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome

(2012) David A. Tumbarello et al.   NATURE CELL BIOLOGY

Cathepsin S Deficiency Results in Abnormal Accumulation of Autophagosomes in Macrophages and Enhances Ang II–Induced Cardiac Inflammation

(2012) Lili Pan et al.   PLoS One

Novel Quinazolinone MJ-29 Triggers Endoplasmic Reticulum Stress and Intrinsic Apoptosis in Murine Leukemia WEHI-3 Cells and Inhibits Leukemic Mice

(2012) Chi-Cheng Lu et al.   PLoS One

Kaempferol acts through mitogen-activated protein kinases and protein kinase B/AKT to elicit protection in a model of neuroinflammation in BV2 microglial cells

(2011) SE Park et al.   BRITISH JOURNAL OF PHARMACOLOGY

Kaempferol induces apoptosis in ovarian cancer cells through activating p53 in the intrinsic pathway

(2011) Haitao Luo et al.   FOOD CHEMISTRY

Kaempferol inhibits VEGF expression and in vitro angiogenesis through a novel ERK-NFκB-cMyc-p21 pathway

(2011) Haitao Luo et al.   FOOD CHEMISTRY

Kaempferol Suppresses Eosionphil Infiltration and Airway Inflammation in Airway Epithelial Cells and in Mice with Allergic Asthma

(2011) Ju-Hyun Gong et al.   JOURNAL OF NUTRITION

Novel quinazoline HMJ-30 induces U-2 OS human osteogenic sarcoma cell apoptosis through induction of oxidative stress and up-regulation of ATM/p53 signaling pathway

(2011) Yu-Jen Chiu et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Carcinoma cells activate AMP-activated protein kinase-dependent autophagy as survival response to kaempferol-mediated energetic impairment

(2010) Giuseppe Filomeni et al.   Autophagy

Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway

(2010) Ljubica Vucicevic et al.   Autophagy

Danthron, an Anthraquinone Derivative, Induces DNA Damage and Caspase Cascades-Mediated Apoptosis in SNU-1 Human Gastric Cancer Cells through Mitochondrial Permeability Transition Pores and Bax-Triggered Pathways

(2010) Jo-Hua Chiang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Simultaneous determination of the flavonoids robinin and kaempferol in human breast cancer cells by liquid chromatography-tandem mass spectrometry

(2010) Lia Tsiklauri et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells

(2010) Chi-Cheng Lu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Kaempferol induced apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathway in human osteosarcoma U-2 OS cells

(2010) Wen-Wen Huang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Kaempferol induced the apoptosis via cell cycle arrest in human breast cancer MDA-MB-453 cells

(2009) Eun Jeong Choi et al.   Nutrition Research and Practice

Kaempferol sensitizes colon cancer cells to TRAIL-induced apoptosis

(2008) Tatsushi Yoshida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Kaempferol induces apoptosis in human HCT116 colon cancer cells via the Ataxia-Telangiectasia Mutated-p53 pathway with the involvement of p53 Upregulated Modulator of Apoptosis

(2008) Wei Li et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Kaempferol and quercetin stimulate granulocyte-macrophage colony-stimulating factor secretion in human prostate cancer cells

(2008) Sanghamitra Bandyopadhyay et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY