Notch1-dependent regulation of p27 determines cell fate in colorectal cancer

CDKN1C/P57 Is Regulated by the Notch Target Gene Hes1 and Induces Senescence in Human Hepatocellular Carcinoma

(2012) Catia Giovannini et al.   AMERICAN JOURNAL OF PATHOLOGY

High-throughput SNP-based authentication of human cell lines

(2012) Felipe Castro et al.   INTERNATIONAL JOURNAL OF CANCER

Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1

(2012) A Fassl et al.   ONCOGENE

miR-221 and miR-155 regulate human dendritic cell development, apoptosis, and IL-12 production through targeting of p27kip1, KPC1, and SOCS-1

(2011) C. Lu et al.   BLOOD

p27 deficiency is associated with migration defects in PDGF-expressing gliomas in vivo

(2011) Wendy L. See et al.   CELL CYCLE

KPC1 Expression and Essential Role After Acute Spinal Cord Injury in Adult Rat

(2011) Jian Zhao et al.   NEUROCHEMICAL RESEARCH

Notch1 regulates the growth of human colon cancers

(2010) Yan Zhang et al.   CANCER

NOTCH Signaling Is Required for Formation and Self-Renewal of Tumor-Initiating Cells and for Repression of Secretory Cell Differentiation in Colon Cancer

(2010) S. S. Sikandar et al.   CANCER RESEARCH

Ubiquitylation and proteasomal degradation of the p21Cip1, p27Kip1and p57Kip2CDK inhibitors

(2010) Zhimin Lu et al.   CELL CYCLE

p27: A Barometer of Signaling Deregulation and Potential Predictor of Response to Targeted Therapies

(2010) S. A. Wander et al.   CLINICAL CANCER RESEARCH

Targeting Notch to Target Cancer Stem Cells

(2010) A. Pannuti et al.   CLINICAL CANCER RESEARCH

The adult stem cell marker Musashi-1 modulates endometrial carcinoma cell cycle progression and apoptosisviaNotch-1 and p21WAF1/CIP1

(2010) Martin Götte et al.   INTERNATIONAL JOURNAL OF CANCER

Therapeutic antibody targeting of individual Notch receptors

(2010) Yan Wu et al.   NATURE

Notch1-induced mammary tumor development is cyclin D1-dependent and correlates with expansion of pre-malignant multipotent duct-limited progenitors

(2010) H Ling et al.   ONCOGENE

Cyclin D1 is a direct target of JAG1-mediated Notch signaling in breast cancer

(2009) Brenda Cohen et al.   BREAST CANCER RESEARCH AND TREATMENT

 -Secretase Inhibitors Abrogate Oxaliplatin-Induced Activation of the Notch-1 Signaling Pathway in Colon Cancer Cells Resulting in Enhanced Chemosensitivity

(2009) R. D. Meng et al.   CANCER RESEARCH

Role of Notch signaling in colorectal cancer

(2009) L. Qiao et al.   CARCINOGENESIS

The Notch Ligands Dll4 and Jagged1 Have Opposing Effects on Angiogenesis

(2009) Rui Benedito et al.   CELL

High-throughput detection and multiplex identification of cell contaminations

(2009) M. Schmitt et al.   NUCLEIC ACIDS RESEARCH

ADAM proteases: ligand processing and modulation of the Notch pathway

(2008) A. Zolkiewska   CELLULAR AND MOLECULAR LIFE SCIENCES

Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2

(2008) Orbicia Riccio et al.   EMBO REPORTS

USP19 Deubiquitinating Enzyme Supports Cell Proliferation by Stabilizing KPC1, a Ubiquitin Ligase for p27Kip1

(2008) Y. Lu et al.   MOLECULAR AND CELLULAR BIOLOGY

mTOR-Raptor Binds and Activates SGK1 to Regulate p27 Phosphorylation

(2008) Feng Hong et al.   MOLECULAR CELL

γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

(2008) Pedro J Real et al.   NATURE MEDICINE

γ-Secretase Inhibitors Enhance Taxane-Induced Mitotic Arrest and Apoptosis in Colon Cancer Cells

(2007) Takashi Akiyoshi et al.   GASTROENTEROLOGY