Role of Notch signaling in colorectal cancer

 -Secretase Inhibitors Abrogate Oxaliplatin-Induced Activation of the Notch-1 Signaling Pathway in Colon Cancer Cells Resulting in Enhanced Chemosensitivity

(2009) R. D. Meng et al.   CANCER RESEARCH

The Notch Ligands Dll4 and Jagged1 Have Opposing Effects on Angiogenesis

(2009) Rui Benedito et al.   CELL

Differences in goblet cell differentiation between Crohn's disease and ulcerative colitis

(2009) Michael Gersemann et al.   DIFFERENTIATION

Targeting apoptosis as an approach for gastrointestinal cancer therapy

(2009) Liang Qiao et al.   DRUG RESISTANCE UPDATES

TNF induction of jagged-1 in endothelial cells is NFκB-dependent

(2009) Douglas A. Johnston et al.   GENE

γ-secretase inhibitors: Notch so bad

(2009) Gerard C Grosveld   NATURE MEDICINE

Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer

(2009) V. Rodilla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

(2009) S. Fre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tract

(2008) Hai Zheng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Requirement of Notch activation during regeneration of the intestinal epithelia

(2008) Ryuichi Okamoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Loss of XIAP sensitizes colon cancer cells to PPARγ independent antitumor effects of troglitazone and 15-PGJ2

(2008) Liang Qiao et al.   CANCER LETTERS

NOTCH Is Part of the Transcriptional Network Regulating Cell Growth and Survival in Mouse Plasmacytomas

(2008) D.-M. Shin et al.   CANCER RESEARCH

A Notch1 Ectodomain Construct Inhibits Endothelial Notch Signaling, Tumor Growth, and Angiogenesis

(2008) Y. Funahashi et al.   CANCER RESEARCH

Notch-1 regulates transcription of the epidermal growth factor receptor through p53

(2008) Benjamin W. Purow et al.   CARCINOGENESIS

Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2

(2008) Orbicia Riccio et al.   EMBO REPORTS

Signaling pathways involved in the development of T-cell acute lymphoblastic leukemia

(2008) F. J.T. Staal et al.   HAEMATOLOGICA

Loss of XIAP sensitizes rosiglitazone-induced growth inhibition of colon cancerin vivo

(2008) Yun Dai et al.   INTERNATIONAL JOURNAL OF CANCER

Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo

(2008) Jonas Sjölund et al.   JOURNAL OF CLINICAL INVESTIGATION

Gastrointestinal stem cells in development and cancer

(2008) S Brabletz et al.   JOURNAL OF PATHOLOGY

Notch Inhibits Expression of the Kruppel-Like Factor 4 Tumor Suppressor in the Intestinal Epithelium

(2008) A. M. Ghaleb et al.   MOLECULAR CANCER RESEARCH

Notch signaling regulates tumor angiogenesis by diverse mechanisms

(2008) J Dufraine et al.   ONCOGENE

The multifaceted role of Notch in cardiac development and disease

(2007) Frances A. High et al.   NATURE REVIEWS GENETICS