Gene expression profiling in treatment-naive schizophrenia patients identifies abnormalities in biological pathways involving AKT1 that are corrected by antipsychotic medication

Finding the needle in the haystack: A review of microarray gene expression research into schizophrenia

(2012) Nishantha Kumarasinghe et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Transcriptional drivers of the T-cell lineage program

(2012) Ellen V Rothenberg   CURRENT OPINION IN IMMUNOLOGY

Elevated levels of circulating IL-18BP and perturbed regulation of IL-18 in schizophrenia

(2012) Ilaria Palladino et al.   Journal of Neuroinflammation

Elevated interleukin-18 serum levels in chronic schizophrenia: Association with psychopathology

(2012) Mei Hong Xiu et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Marked Reduction of AKT1 Expression and Deregulation of AKT1-Associated Pathways in Peripheral Blood Mononuclear Cells of Schizophrenia Patients

(2012) Nico J. M. van Beveren et al.   PLoS One

A Gene Co-Expression Network in Whole Blood of Schizophrenia Patients Is Independent of Antipsychotic-Use and Enriched for Brain-Expressed Genes

(2012) Simone de Jong et al.   PLoS One

Inflammatory markers in antipsychotic-naïve patients with nonaffective psychosis and deficit vs. nondeficit features

(2012) Clemente Garcia-Rizo et al.   PSYCHIATRY RESEARCH

Novel human BTB/POZ domain-containing zinc finger protein ZBTB1 inhibits transcriptional activities of CRE

(2011) Qingmei Liu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Genome-wide association study identifies five new schizophrenia loci

(2011)   NATURE GENETICS

Linking neurodevelopmental and synaptic theories of mental illness through DISC1

(2011) Nicholas J. Brandon et al.   NATURE REVIEWS NEUROSCIENCE

Genome-Wide Identification of Bcl11b Gene Targets Reveals Role in Brain-Derived Neurotrophic Factor Signaling

(2011) Bin Tang et al.   PLoS One

Serum levels of IL-6, IL-10 and TNF-α in patients with bipolar disorder and schizophrenia: differences in pro- and anti-inflammatory balance

(2011) Mauricio Kunz et al.   REVISTA BRASILEIRA DE PSIQUIATRIA

Cognitive impairment following prenatal immune challenge in mice correlates with prefrontal cortical AKT1 deficiency

(2010) Byron K. Y. Bitanihirwe et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Neuroplasticity signaling pathways linked to the pathophysiology of schizophrenia

(2010) Darrick T. Balu et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The environment and susceptibility to schizophrenia

(2010) Alan S. Brown   PROGRESS IN NEUROBIOLOGY

Diagnostic classification of schizophrenia by neural network analysis of blood-based gene expression signatures

(2010) Makoto Takahashi et al.   SCHIZOPHRENIA RESEARCH

Convergent Evidence Shows a Positive Association of Interleukin-1 Gene Complex Locus with Susceptibility to Schizophrenia in the Caucasian population

(2010) Mingqing Xu et al.   SCHIZOPHRENIA RESEARCH

Regulation of immune-modulatory genes in left superior temporal cortex of schizophrenia patients: a genome-wide microarray study

(2010) Andrea Schmitt et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Persistently increased serum soluble interleukin-2 receptors in continuously ill patients with schizophrenia

(2009) Catherine Bresee et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Folate, homocysteine, interleukin-6, and tumor necrosis factor alfa levels, but not the methylenetetrahydrofolate reductase C677T polymorphism, are risk factors for schizophrenia

(2009) María del Rosario García-Miss et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Identification of blood biomarkers for psychosis using convergent functional genomics

(2009) S M Kurian et al.   MOLECULAR PSYCHIATRY

Schizophrenia is associated with an increase in cortical microRNA biogenesis

(2009) N J Beveridge et al.   MOLECULAR PSYCHIATRY

DISC1 Regulates New Neuron Development in the Adult Brain via Modulation of AKT-mTOR Signaling through KIAA1212

(2009) Ju Young Kim et al.   NEURON

Antipsychotic drug actions on gene modulation and signaling mechanisms

(2009) Raffaella Molteni et al.   PHARMACOLOGY & THERAPEUTICS

The DISC1 Pathway Modulates Expression of Neurodevelopmental, Synaptogenic and Sensory Perception Genes

(2009) William Hennah et al.   PLoS One

DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms

(2009) K. Nakata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

No Significant Association of 14 Candidate Genes With Schizophrenia in a Large European Ancestry Sample: Implications for Psychiatric Genetics

(2008) Alan R. Sanders et al.   AMERICAN JOURNAL OF PSYCHIATRY

Altered gene expression in the superior temporal gyrus in schizophrenia

(2008) Nikola A Bowden et al.   BMC GENOMICS

Neuroprotection of interleukin-6 against NMDA attack and its signal transduction by JAK and MAPK

(2008) Xiao-Qin Wang et al.   NEUROSCIENCE LETTERS

The Fezf2-Ctip2 genetic pathway regulates the fate choice of subcortical projection neurons in the developing cerebral cortex

(2008) B. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AKT1 Is Associated with Schizophrenia Across Multiple Symptom Dimensions in the Irish Study of High Density Schizophrenia Families

(2007) Dawn L. Thiselton et al.   BIOLOGICAL PSYCHIATRY

Inflammatory Cytokine Alterations in Schizophrenia: A Systematic Quantitative Review

(2007) Stéphane Potvin et al.   BIOLOGICAL PSYCHIATRY