Cytosolic 5′-Nucleotidase II Silencing in a Human Lung Carcinoma Cell Line Opposes Cancer Phenotype with a Concomitant Increase in p53 Phosphorylation

The cytosolic 5’-nucleotidase cN-II lowers the adaptability to glucose deprivation in human breast cancer cells

(2017) Gabriel Bricard et al.   Oncotarget

Stably transfected adherent cancer cell models with decreased expression of 5′-nucleotidase cN-II

(2016) Gabriel Bricard et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

The enhancing effect of genistein on apoptosis induced by trichostatin A in lung cancer cells with wild type p53 genes is associated with upregulation of histone acetyltransferase

(2016) Tzu-Chin Wu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Determination of the enzymatic activity of cytosolic 5′-nucleotidase cN-II in cancer cells: development of a simple analytical method and related cell line models

(2015) Lars Petter Jordheim et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

IMP–GMP specific cytosolic 5′-nucleotidase regulates nucleotide pool and prodrug metabolism

(2015) Federico Cividini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The druggability of intracellular nucleotide-degrading enzymes

(2015) Chiara Rampazzo et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Cell proliferation and drug sensitivity of human glioblastoma cells are altered by the stable modulation of cytosolic 5′-nucleotidase II

(2015) F. Cividini et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cytosolic 5’-Nucleotidase II Interacts with the Leucin Rich Repeat of NLR Family Member Ipaf

(2015) Federico Cividini et al.   PLoS One

2-Deoxy-D-glucose targeting of glucose metabolism in cancer cells as a potential therapy

(2014) Dongsheng Zhang et al.   CANCER LETTERS

Glycolysis inhibitor 2-deoxy-D-glucose suppresses carcinogen-induced rat hepatocarcinogenesis by restricting cancer cell metabolism

(2014) ZHAOFA WANG et al.   Molecular Medicine Reports

Decreased survival in normal karyotype AML with single-nucleotide polymorphisms in genes encoding the AraC metabolizing enzymes cytidine deaminase and 5′-nucleotidase

(2013) Ingrid Jakobsen Falk et al.   AMERICAN JOURNAL OF HEMATOLOGY

Enzymatic Properties and Physiological Roles of Cytosolic 5’-Nucleotidase II.

(2013) Roichi Itoh   CURRENT MEDICINAL CHEMISTRY

On the Physiological Role of Cytosolic 5’-nucleotidase II (cN-II): Pathological and Therapeutical Implications.

(2013) M. Tozzi et al.   CURRENT MEDICINAL CHEMISTRY

Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL

(2013) Gannie Tzoneva et al.   NATURE MEDICINE

Expression of Bovine Cytosolic 5′-Nucleotidase (cN-II) in Yeast: Nucleotide Pools Disturbance and Its Consequences on Growth and Homologous Recombination

(2013) Simone Allegrini et al.   PLoS One

Bioenergetic role of mitochondrial fusion and fission

(2012) Benedikt Westermann   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

(2012) Sang-Min Jeon et al.   NATURE

Novel metabolic aspects related to adenosine deaminase inhibition in a human astrocytoma cell line

(2012) Mercedes Garcia-Gil et al.   NEUROCHEMISTRY INTERNATIONAL

p53 and its mutants in tumor cell migration and invasion

(2011) Patricia A. J. Muller et al.   JOURNAL OF CELL BIOLOGY

Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5′-Nucleotidase II

(2011) Karin Walldén et al.   JOURNAL OF MOLECULAR BIOLOGY

Pemetrexed Indirectly Activates the Metabolic Kinase AMPK in Human Carcinomas

(2010) S. B. Rothbart et al.   CANCER RESEARCH

Glutathione dysregulation and the etiology and progression of human diseases

(2009) Nazzareno Ballatori et al.   BIOLOGICAL CHEMISTRY

p53 Regulation of Metabolic Pathways

(2009) E. Gottlieb et al.   Cold Spring Harbor Perspectives in Biology

Knockdown of cytosolic 5′-nucleotidase II (cN-II) reveals that its activity is essential for survival in astrocytoma cells

(2008) Maria Giovanna Careddu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

p53: The Janus of autophagy?

(2008) Beth Levine et al.   NATURE CELL BIOLOGY