Effects and Mechanism of Nano-Copper Exposure on Hepatic Cytochrome P450 Enzymes in Rats

Shape-Dependent Dissolution and Cellular Uptake of Silver Nanoparticles

(2018) Christina Graf et al.   LANGMUIR

Regulation of drug-metabolizing enzymes in infectious and inflammatory disease: implications for biologics–small molecule drug interactions

(2017) Pankajini Mallick et al.   Expert Opinion on Drug Metabolism & Toxicology

Hepatotoxicity of Herbal Supplements Mediated by Modulation of Cytochrome P450

(2017) Christopher Brewer et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Copper nanoparticles in glycerol-polyvinyl alcohol matrix: In situ preparation, stabilisation and antimicrobial activity

(2017) Kryštof Dobrovolný et al.   JOURNAL OF ALLOYS AND COMPOUNDS

Intersection of the Roles of Cytochrome P450 Enzymes with Xenobiotic and Endogenous Substrates: Relevance to Toxicity and Drug Interactions

(2016) F. Peter Guengerich   CHEMICAL RESEARCH IN TOXICOLOGY

Regulation of drug-metabolizing enzymes by local and systemic liver injuries

(2016) Yan Guo et al.   Expert Opinion on Drug Metabolism & Toxicology

Comparative toxicity and biodistribution of copper nanoparticles and cupric ions in rats

(2016) Jong-Choon Kim et al.   International Journal of Nanomedicine

Comparative toxicity and biodistribution assessments in rats following subchronic oral exposure to copper nanoparticles and microparticles

(2016) In-Chul Lee et al.   Particle and Fibre Toxicology

A comprehensive assay for nine major cytochrome P450 enzymes activities with 16 probe reactions on human liver microsomes by a single LC/MS/MS run to support reliablein vitroinhibitory drug–drug interaction evaluation

(2015) Ying Peng et al.   XENOBIOTICA

Mitochondrial dysfunction and oxidative damage in the liver and kidney of rats following exposure to copper nanoparticles for five consecutive days

(2015) Ronghui Lei et al.   Toxicology Research

Carboxymefloquine, the Major Metabolite of the Antimalarial Drug Mefloquine, Induces Drug-Metabolizing Enzyme and Transporter Expression by Activation of Pregnane X Receptor

(2014) Rita Piedade et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Particle size dependent deposition and pulmonary inflammation after short-term inhalation of silver nanoparticles

(2014) Hedwig M Braakhuis et al.   Particle and Fibre Toxicology

Taurine attenuates nano-copper-induced oxidative hepatic damage via mitochondria-dependent and NF-κB/TNF-α-mediated pathway

(2014) Manoranjan Ghosh et al.   Toxicology Research

In vitro and in vivo models for the study of oral delivery of nanoparticles

(2013) Jennifer M. Gamboa et al.   ADVANCED DRUG DELIVERY REVIEWS

Advances in Copper Complexes as Anticancer Agents

(2013) Carlo Santini et al.   CHEMICAL REVIEWS

Genetics, Epigenetics, and Regulation of Drug-Metabolizing Cytochrome P450 Enzymes

(2013) U M Zanger et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Chitosan coating of copper nanoparticles reducesin vitrotoxicity and increases inflammation in the lung

(2013) Kristan L S Worthington et al.   NANOTECHNOLOGY

Survey of Innate Immune Responses to Burkholderia pseudomallei in Human Blood Identifies a Central Role for Lipopolysaccharide

(2013) Narisara Chantratita et al.   PLoS One

Mode of action of ethyl tertiary-butyl ether hepatotumorigenicity in the rat: Evidence for a role of oxidative stress via activation of CAR, PXR and PPAR signaling pathways

(2013) Anna Kakehashi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mechanisms of Nanoparticle-Induced Oxidative Stress and Toxicity

(2013) Amruta Manke et al.   Biomed Research International

Physicochemical Properties Determine Nanomaterial Cellular Uptake, Transport, and Fate

(2012) Motao Zhu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Role of CAR and PXR in xenobiotic sensing and metabolism

(2012) Yue-Ming Wang et al.   Expert Opinion on Drug Metabolism & Toxicology

The Toxic Effects and Mechanisms of CuO and ZnO Nanoparticles

(2012) Ya-Nan Chang et al.   Materials

The Applications of Nanotechnology in Food Industry

(2011) Ladan Rashidi et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Gene expression profiling of nephrotoxicity from copper nanoparticles in rats after repeated oral administration

(2011) MingYang Liao et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Contribution of nano-copper particles toin vivoliver dysfunction and cellular damage: Role of IκBα/NF-κB, MAPKs and mitochondrial signal

(2011) Prasenjit Manna et al.   Nanotoxicology

Transporter-mediated drug–drug interactions

(2011) Fabian Müller et al.   PHARMACOGENOMICS

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Toxicologic effects of gold nanoparticles in vivo by different administration routes

(2010) Zhang   International Journal of Nanomedicine

In vitro effects of natural prenyloxycinnamic acids on human cytochrome P450 isozyme activity and expression

(2010) S. Genovese et al.   PHYTOMEDICINE

Exposure to ZnO nanoparticles induces oxidative stress and cytotoxicity in human colon carcinoma cells

(2010) Barbara De Berardis et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Role of NF-κB in the Regulation of Cytochrome P450 Enzymes

(2009) Beshay Zordoky et al.   CURRENT DRUG METABOLISM

Copper nanoparticles exert size and concentration dependent toxicity on somatosensory neurons of rat

(2009) Badanavalu M. Prabhu et al.   Nanotoxicology

Will the public swallow nanofood?

(2009) Ai Lin Chun   Nature Nanotechnology

Copper oxide nanoparticles induce oxidative stress and cytotoxicity in airway epithelial cells

(2009) Baher Fahmy et al.   TOXICOLOGY IN VITRO

Growth factors, cytokines and their receptors as downstream targets of arylhydrocarbon receptor (AhR) signaling pathways

(2008) Thomas Haarmann-Stemmann et al.   BIOCHEMICAL PHARMACOLOGY

Comparative study of cytotoxicity, oxidative stress and genotoxicity induced by four typical nanomaterials: the role of particle size, shape and composition

(2008) Hui Yang et al.   JOURNAL OF APPLIED TOXICOLOGY

Integrated metabolomic analysis of the nano-sized copper particle-induced hepatotoxicity and nephrotoxicity in rats: A rapid in vivo screening method for nanotoxicity

(2008) Ronghui Lei et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effects of mixing metal ions on oxidative DNA damage mediated by a Fenton-type reduction

(2007) Hiroshi Moriwaki et al.   TOXICOLOGY IN VITRO