Ginsenoside Rd Attenuates Mitochondrial Permeability Transition and Cytochrome c Release in Isolated Spinal Cord Mitochondria: Involvement of Kinase-Mediated Pathways

Mitochondrial Dysfunction is a Converging Point of Multiple Pathological Pathways in Amyotrophic Lateral Sclerosis

(2017) Ping Shi et al.   JOURNAL OF ALZHEIMERS DISEASE

α7 nicotinic acetylcholine receptors control cytochrome c release from isolated mitochondria through kinase-mediated pathways

(2014) Galyna Gergalova et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Ginsenoside Rd Attenuates Tau Protein Phosphorylation Via the PI3K/AKT/GSK-3β Pathway After Transient Forebrain Ischemia

(2014) Xiao Zhang et al.   NEUROCHEMICAL RESEARCH

Ethylmalonic Acid Induces Permeability Transition in Isolated Brain Mitochondria

(2014) Cristiane Cecatto et al.   NEUROTOXICITY RESEARCH

Recent advances in natural products from plants for treatment of liver diseases

(2013) Aihua Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Ginsenoside Rd for acute ischemic stroke: translating from bench to bedside

(2013) Ruidong Ye et al.   Expert Review of Neurotherapeutics

Osthole attenuates spinal cord ischemia–reperfusion injury through mitochondrial biogenesis–independent inhibition of mitochondrial dysfunction in rats

(2013) Yue-fei Zhou et al.   JOURNAL OF SURGICAL RESEARCH

Salvianolic acid B attenuates spinal cord ischemia-reperfusion–induced neuronal injury and oxidative stress by activating the extracellular signal–regulated kinase pathway in rats

(2013) Jun Fu et al.   JOURNAL OF SURGICAL RESEARCH

Neuroglobin overexpression inhibits oxygen–glucose deprivation-induced mitochondrial permeability transition pore opening in primary cultured mouse cortical neurons

(2013) Zhanyang Yu et al.   NEUROBIOLOGY OF DISEASE

Ginsenoside Rd Attenuates Myocardial Ischemia/Reperfusion Injury via Akt/GSK-3β Signaling and Inhibition of the Mitochondria-Dependent Apoptotic Pathway

(2013) Yang Wang et al.   PLoS One

Ginsenoside Rd promotes glutamate clearance by up-regulating glial glutamate transporter GLT-1 via PI3K/AKT and ERK1/2 pathways

(2013) Xiao Zhang   Frontiers in Pharmacology

Therapeutic potential of targeting hydrogen peroxide metabolism in the treatment of brain ischaemia

(2012) Marta Armogida et al.   BRITISH JOURNAL OF PHARMACOLOGY

The permeability transition pore as a Ca2+ release channel: New answers to an old question

(2012) Paolo Bernardi et al.   CELL CALCIUM

Protective Effects of mGluR5 Positive Modulators Against Traumatic Neuronal Injury Through PKC-Dependent Activation of MEK/ERK Pathway

(2012) Tao Chen et al.   NEUROCHEMICAL RESEARCH

Neuroprotective effects of allicin on spinal cord ischemia–reperfusion injury via improvement of mitochondrial function in rabbits

(2012) Jin-Wen Zhu et al.   NEUROCHEMISTRY INTERNATIONAL

Mitochondria Express α7 Nicotinic Acetylcholine Receptors to Regulate Ca2+ Accumulation and Cytochrome c Release: Study on Isolated Mitochondria

(2012) Galyna Gergalova et al.   PLoS One

The pig model of chronic paraplegia: A challenge for experimental studies in spinal cord injury

(2012) Mercedes Zurita et al.   PROGRESS IN NEUROBIOLOGY

Ginsenoside Re: Pharmacological Effects on Cardiovascular System

(2011) Lu Peng et al.   Cardiovascular Therapeutics

Ginsenoside Rd Protects Neurons Against Glutamate-Induced Excitotoxicity by Inhibiting Ca2+ Influx

(2011) Chen Zhang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

The selective mGluR5 agonist CHPG protects against traumatic brain injury in vitro and in vivo via ERK and Akt pathway

(2011) TAO CHEN et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Spinal Cord Ischemia Following Coronary Artery Bypass Surgery

(2011) Pankaj Saxena et al.   JOURNAL OF CARDIAC SURGERY

Ginsenoside Rd attenuates redox imbalance and improves stroke outcome after focal cerebral ischemia in aged mice

(2011) Ruidong Ye et al.   NEUROPHARMACOLOGY

Ginsenoside Rd attenuates mitochondrial dysfunction and sequential apoptosis after transient focal ischemia

(2011) R. Ye et al.   NEUROSCIENCE

Targeting Mitochondrial Function for the Treatment of Acute Spinal Cord Injury

(2011) Melanie L. McEwen et al.   Neurotherapeutics

Ginsenoside Rd in Experimental Stroke: Superior Neuroprotective Efficacy with a Wide Therapeutic Window

(2011) Ruidong Ye et al.   Neurotherapeutics

Pharmacokinetic, tissue distribution and excretion of ginsenoside-Rd in rodents

(2011) Dong Sun et al.   PHYTOMEDICINE

Hydrogen peroxide: a Jekyll and Hyde signalling molecule

(2011) D R Gough et al.   Cell Death & Disease

Neuroprotective effect of osthole against acute ischemic stroke on middle cerebral ischemia occlusion in rats

(2010) Xiaodong Chao et al.   BRAIN RESEARCH

Ginsenoside Rd attenuates early oxidative damage and sequential inflammatory response after transient focal ischemia in rats

(2010) Ruidong Ye et al.   NEUROCHEMISTRY INTERNATIONAL

Mitochondrial kinases in cell signaling: Facts and perspectives☆

(2009) Valeria G. Antico Arciuch et al.   ADVANCED DRUG DELIVERY REVIEWS

Current Evaluation of the Millennium Phytomedicine- Ginseng (I): Etymology, Pharmacognosy, Phytochemistry, Market and Regulations

(2009) Lee Jia et al.   CURRENT MEDICINAL CHEMISTRY

Ginseng Compounds: An Update on their Molecular Mechanisms and Medical Applications

(2009) Jian-Ming Lu et al.   Current Vascular Pharmacology

Efficacy and safety of ginsenoside-Rd for acute ischaemic stroke: a randomized, double-blind, placebo-controlled, phase II multicenter trial

(2009) X. Liu et al.   EUROPEAN JOURNAL OF NEUROLOGY

Advances in Imaging of the Spinal Cord Vascular Supply and its Relationship with Paraplegia after Aortic Interventions. A Review

(2009) G. Melissano et al.   EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY

Akt mediated mitochondrial protection in the heart: metabolic and survival pathways to the rescue

(2009) Shigeki Miyamoto et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Neuroprotective effects of ginsenoside Rd against oxygen-glucose deprivation in cultured hippocampal neurons

(2009) Ruidong Ye et al.   NEUROSCIENCE RESEARCH

Protective Effects of Ginsenoside Rd on PC12 Cells against Hydrogen Peroxide

(2008) Ruidong Ye et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Role of Free Radicals and Poly(ADP-Ribose)Polymerase-1 in the Development of Spinal Cord Injury: New Potential Therapeutic Targets

(2008) S. Cuzzocrea et al.   CURRENT MEDICINAL CHEMISTRY

Spinal cord blood flow and ischemic injury after experimental sacrifice of thoracic and abdominal segmental arteries☆

(2008) Christian D. Etz et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

Spinal Arterial Anatomy and Risk Factors for Lower Extremity Weakness Following Endovascular Thoracoabdominal Aortic Aneurysm Repair With Branched Stent-Grafts

(2008) Catherine K. Chang et al.   JOURNAL OF ENDOVASCULAR THERAPY

Biomass and content of ginsenosides and polyacetylenes in American ginseng roots can be increased without affecting the profile of bioactive compounds

(2008) Lars P. Christensen et al.   Journal of Natural Medicines

Mitochondrial Dysfunction in SOD1G93A-Bearing Astrocytes Promotes Motor Neuron Degeneration: Prevention by Mitochondrial-Targeted Antioxidants

(2008) P. Cassina et al.   JOURNAL OF NEUROSCIENCE

Magnetic resonance angiography of collateral blood supply to spinal cord in thoracic and thoracoabdominal aortic aneurysm patients

(2008) Walter H. Backes et al.   JOURNAL OF VASCULAR SURGERY

Tumor Cell Phenotype Is Sustained by Selective MAPK Oxidation in Mitochondria

(2008) Soledad Galli et al.   PLoS One

Structurally diverse natural products that cause potassium leakage trigger multicellularity in Bacillus subtilis

(2008) D. Lopez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA