Overcoming Hypoxic-Resistance of Tumor Cells to TRAIL-Induced Apoptosis through Melatonin

Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis

(2013) Á. C. Murphy et al.   APOPTOSIS

Sensitization of melanoma cells for TRAIL-induced apoptosis by activation of mitochondrial pathways via Bax

(2013) Sandra-Annika Quast et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Hypoxia-inducible Factor 1 regulated ARC expression mediated hypoxia induced inactivation of the intrinsic death pathway in p53 deficient human colon cancer cells

(2012) Jin-e Ao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Expression of Prolyl Hydroxylases (PHDs) Is Selectively Controlled by HIF-1 and HIF-2 Proteins in Nucleus Pulposus Cells of the Intervertebral Disc

(2012) Nobuyuki Fujita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Melatonin suppresses tumor progression by reducing angiogenesis stimulated by HIF-1 in a mouse tumor model

(2012) Kil-Jung Kim et al.   JOURNAL OF PINEAL RESEARCH

Reactive oxygen species and p38 MAPK regulate Bax translocation and calcium redistribution in salubrinal-induced apoptosis of EBV-transformed B cells

(2011) Ga Bin Park et al.   CANCER LETTERS

Sphingosine kinase 1 pathway is involved in melatonin-induced HIF-1α inactivation in hypoxic PC-3 prostate cancer cells

(2011) Sung-Yun Cho et al.   JOURNAL OF PINEAL RESEARCH

Melatonin and its analogs in insomnia and depression

(2011) Daniel P. Cardinali et al.   JOURNAL OF PINEAL RESEARCH

Melatonin triggers p53Ser phosphorylation and prevents DNA damage accumulation

(2011) R Santoro et al.   ONCOGENE

Treatment of kidney cancer

(2010) William G. Kaelin   CANCER

Melatonin reduces pancreatic tumor cell viability by altering mitochondrial physiology

(2010) Antonio Gonzalez et al.   JOURNAL OF PINEAL RESEARCH

Melatonin suppresses tumor angiogenesis by inhibiting HIF-1α stabilization under hypoxia

(2010) Shi-Young Park et al.   JOURNAL OF PINEAL RESEARCH

HIF-1: a key mediator in hypoxia (Review)

(2009) J. Adams et al.   ACTA PHYSIOLOGICA HUNGARICA

Reducing oxidative/nitrosative stress: a newly-discovered genre for melatonin

(2009) Russel J. Reiter et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Hypoxia induces chemoresistance in ovarian cancer cells by activation of signal transducer and activator of transcription 3

(2009) Karuppaiyah Selvendiran et al.   INTERNATIONAL JOURNAL OF CANCER

Hypoxia protects neuronal cells from human prion protein fragment-induced apoptosis

(2009) Jae-Suk Seo et al.   JOURNAL OF NEUROCHEMISTRY

Potential roles of melatonin and chronotherapy among the new trends in hypertension treatment

(2009) Fedor Simko et al.   JOURNAL OF PINEAL RESEARCH

Melatonin reduces cardiac inflammatory injury induced by acute exercise

(2009) C. Veneroso et al.   JOURNAL OF PINEAL RESEARCH

Melatonin down-regulates HIF-1α expression through inhibition of protein translation in prostate cancer cells

(2009) Jong-Wook Park et al.   JOURNAL OF PINEAL RESEARCH

Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines

(2009) Rüdiger Hardeland et al.   JOURNAL OF PINEAL RESEARCH

Inhibition of hypoxia-inducible factor-1 function enhances the sensitivity of multiple myeloma cells to melphalan

(2009) Y. Hu et al.   MOLECULAR CANCER THERAPEUTICS

Hypoxia increases normal prostate epithelial cell resistance to receptor-mediated apoptosisviaAKT activation

(2008) Sinead Walsh et al.   INTERNATIONAL JOURNAL OF CANCER

Potential role of tryptophan derivatives in stress responses characterized by the generation of reactive oxygen and nitrogen species

(2008) Fabienne Peyrot et al.   JOURNAL OF PINEAL RESEARCH