Article
Biochemistry & Molecular Biology
Namasthee Harris-Gauthier, Annika Traa, Abdelrahman AlOkda, Alibek Moldakozhayev, Ulrich Anglas, Sonja K. Soo, Jeremy M. Van Raamsdonk
Summary: Mild impairment of mitochondrial function can increase lifespan in genetic model organisms. The upregulation of genes involved in the mitochondrial thioredoxin system, mediated by the mitochondrial unfolded protein response, is specifically required for the longevity of mitochondrial mutants. The mitochondrial thioredoxin system also plays a role in stress resistance.
Article
Biotechnology & Applied Microbiology
Nour Elaimane Bouzidi, Samir Borhane Grama, Aboubakeur Essedik Khelef, Duanpeng Yang, Jian Li
Summary: This study investigates the effect of inhibiting antioxidant enzyme activity on carotenoid synthesis in microalgae. The findings suggest that inhibiting enzyme activity can significantly increase carotenoid accumulation, providing a new approach for carotenoid production.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Environmental Sciences
Javaid Akhter Bhat, Masroor Ahmad Bhat, Dyaaaldin Abdalmegeed, Deyue Yu, Jian Chen, Andrzej Bajguz, Ajaz Ahmad, Parvaiz Ahmad
Summary: The study demonstrated that the combined application of Fe2O3-NPs and CA had a better alleviating effect on As toxicity in soybean. Fe2O3-NPs and CA significantly reversed As-induced growth inhibition and oxidative stress responses, partially reducing the production of MDA and H2O2.
ENVIRONMENTAL POLLUTION
(2022)
Article
Biochemistry & Molecular Biology
Touhidur Rahman Anik, Mohammad Golam Mostofa, Mezanur Rahman, Arifur Rahman Khan, Protik Kumar Ghosh, Sharmin Sultana, Ashim Kumar Das, Saddam Hossain, Sanjida Sultana Keya, Abiar Rahman, Nusrat Jahan, Aarti Gupta, Lam-Son Phan Tran
Summary: Drought is a major threat to sustainable agricultural productivity, and finding a long-term solution to increase plants' tolerance to drought stress has been a key research focus. The present study provides persuasive evidence on the potential roles of zinc supplements in promoting tolerance of cotton plants exposed to drought. The results suggest that soil supplementation of zinc sulfate or zinc oxide improves various physiological, morphological, and biochemical features of cotton plants under drought stress, indicating their potential as effective techniques for boosting plant resilience to drought.
Review
Biochemistry & Molecular Biology
Anushruti Ashok, Syed Suhail Andrabi, Saffar Mansoor, Youzhi Kuang, Brian K. Kwon, Vinod Labhasetwar
Summary: Free radicals, generated during normal metabolic activities, play a crucial role in neurodegenerative diseases through oxidative stress, which disrupts redox balance. Antioxidant therapy, including nanoparticle-mediated delivery of antioxidant enzymes, shows promise in addressing the challenges of clinical translation in treating these diseases.
Article
Plant Sciences
Hui-Ling Gong, Qiao-Qiao Chen
Summary: Exogenous sucrose pretreatment enhances thermotolerance and reduces morphological injuries in potato seedlings under heat stress by regulating antioxidant enzyme system, reducing reactive oxygen species accumulation, and increasing sucrose and proline levels.
JOURNAL OF SOIL SCIENCE AND PLANT NUTRITION
(2021)
Review
Plant Sciences
Jiawei Li, Qinglin Zhu, Fuchao Jiao, Zhenwei Yan, Haiyan Zhang, Yumei Zhang, Zhaohua Ding, Chunhua Mu, Xia Liu, Yan Li, Jingtang Chen, Ming Wang
Summary: Maize is globally the most important cereal crop, but it has been facing various challenges from environmental factors, including salt stress caused by climate change. This review provides an overview of the intricate relationships between salt stress and several plant defense mechanisms in maize, such as osmolytes, antioxidant enzymes, reactive oxygen species, plant hormones, and ions (Na+, K+, Cl-), which are critical for salt tolerance. It addresses the regulatory strategies and key factors involved in salt tolerance, aiming to enhance the understanding of the salt tolerance regulatory networks in maize.
Article
Plant Sciences
Renata Biba, Petra Cvjetko, Mihaela Jakopcic, Bruno Komazec, Mirta Tkalec, Nino Dimitrov, Tajana Begovic, Biljana Balen
Summary: Plastic contamination is a pressing environmental issue due to the increasing production of disposable plastic products. In this study, onion roots were exposed to commercial polystyrene (PS-MPs) and polymethyl methacrylate microparticles (PMMA-MPs) to investigate their effects. The results showed that PS-MPs were more readily taken up by onion roots compared to PMMA-MPs. Both types of microparticles did not induce toxic effects on root growth, and PMMA-MPs even stimulated root growth. Antioxidant enzymes were activated in root cells after exposure to both types of microparticles.
Article
Plant Sciences
Yu Wang, Yuanzheng Zhao, Baozhu Dong, Dong Wang, Jianxiu Hao, Xinyu Jia, Yuxi Zhao, Yin Nian, Hongyou Zhou
Summary: In this study, it was demonstrated that B. oleracea extract has inhibitory effects on the germination and growth of P. miliaceum. The extract altered the activities of oxidative enzymes and increased the content of phytohormones in P. miliaceum seedlings. The presence of auxins and their analogs in the extract may contribute to the suppression of P. miliaceum growth.
Article
Biochemistry & Molecular Biology
Aditya Sharma, Sushmita Singh, Shadab Ahmad, Farah Gulzar, Jonathan D. Schertzer, Akhilesh K. Tamrakar
Summary: Our study indicates that activation of NOD1 triggers oxidative stress in adipocytes through NOX1/4, contributing to the induction of inflammatory response.
FREE RADICAL BIOLOGY AND MEDICINE
(2021)
Article
Cell Biology
Hiroko Morimoto, Takuya Yamamoto, Takehiro Miyazaki, Narumi Ogonuki, Atsuo Ogura, Takashi Tanaka, Mito Kanatsu-Shinohara, Chihiro Yabe-Nishimura, Hongliang Zhang, Yves Pommier, Andreas Trumpp, Takashi Shinohara
Summary: The origin of ROS and oxygen tension play a critical role in driving spermatogonial stem cell (SSC) self-renewal. Under hypoxia, NOX1-derived ROS significantly decrease, impacting the proliferation of SSCs.
GENES & DEVELOPMENT
(2021)
Review
Biochemistry & Molecular Biology
Patrizia Bottoni, Giulia Gionta, Roberto Scatena
Summary: Mitochondrial myopathies are a heterogeneous group of diseases caused by genetic mutations in proteins involved in mitochondrial oxidative metabolism. These myopathies show significant differences in their evolution, but some physiological and pathophysiological aspects of mitochondria reveal other potential molecular mechanisms that may play a significant role in their clinical progression.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Arun Gokul, Mogamat Fahiem Carelse, Lee-Ann Niekerk, Ashwil Klein, Ndiko Ludidi, David Mendoza-Cozatl, Marshall Keyster
Summary: Exogenous application of 3,3'-diindolylmethane (DIM) under vanadium stress improved seed germination percentage, shoot dry weight, cell viability, and chlorophyll content of B. napus cultivar AV Garnet, while decreasing oxidative stress markers. Additionally, DIM led to increased enzymatic activities of antioxidant enzymes under vanadium stress, without altering vanadium content in B. napus shoots. These results suggest that DIM can enhance B. napus seedling growth under vanadium stress by activating antioxidant enzymes via ROS signaling.
Article
Biochemistry & Molecular Biology
Muneera D. F. AlKahtani, Yaser M. Hafez, Kotb Attia, Emadeldeen Rashwan, Latifa Al Husnain, Hussah I. M. AlGwaiz, Khaled A. A. Abdelaal
Summary: The silicon effect and proline, either individually or in combination, significantly alleviated the harmful effects of drought on sugar beet plants by increasing yield parameters and reducing oxidative stress.
Article
Biochemistry & Molecular Biology
Iwona Lukasik, Sylwia Golawska, Hubert Sytykiewicz
Summary: Changes in oxidative stress markers and antioxidant enzyme activities were studied in the black bean aphid. Winged adults showed lower oxidative stress marker levels and higher antioxidant enzyme activities, indicating adaptation to new host plants. Wingless females during spring migration showed increased marker levels and enzyme activities, suggesting biochemical adaptation to winter hosts.