Long Non-Coding RNA in Cancer

Large Intervening Non-Coding RNA HOTAIR is Associated with Hepatocellular Carcinoma Progression

(2013) YJ Geng et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Upregulation of miR-196a and HOTAIR Drive Malignant Character in Gastrointestinal Stromal Tumors

(2012) T. Niinuma et al.   CANCER RESEARCH

Long noncoding RNAs are rarely translated in two human cell lines

(2012) B. Banfai et al.   GENOME RESEARCH

MEG3 noncoding RNA: a tumor suppressor

(2012) Yunli Zhou et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Novel classes of non-coding RNAs and cancer

(2012) Jiri Sana et al.   Journal of Translational Medicine

The long non-coding RNAs, a new cancer diagnostic and therapeutic gold mine

(2012) Peng Qi et al.   MODERN PATHOLOGY

The hallmarks of cancer

(2012) Tony Gutschner et al.   RNA Biology

Loss of the abundant nuclear non-coding RNAMALAT1is compatible with life and development

(2012) Moritz Eißmann et al.   RNA Biology

Malat1 is not an essential component of nuclear speckles in mice

(2012) S. Nakagawa et al.   RNA

Overexpression of Long Non-coding RNA HOTAIR Predicts Tumor Recurrence in Hepatocellular Carcinoma Patients Following Liver Transplantation

(2011) Zhe Yang et al.   ANNALS OF SURGICAL ONCOLOGY

The Melanoma-Upregulated Long Noncoding RNA SPRY4-IT1 Modulates Apoptosis and Invasion

(2011) D. Khaitan et al.   CANCER RESEARCH

Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers

(2011) R. Kogo et al.   CANCER RESEARCH

MEG3 imprinted gene contribution in tumorigenesis

(2011) Leonidas Benetatos et al.   INTERNATIONAL JOURNAL OF CANCER

Long non-coding RNA MALAT-1 overexpression predicts tumor recurrence of hepatocellular carcinoma after liver transplantation

(2011) Ming-chun Lai et al.   MEDICAL ONCOLOGY

The functional role of long non-coding RNA in human carcinomas

(2011) Ewan A Gibb et al.   Molecular Cancer

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

(2011) John R Prensner et al.   NATURE BIOTECHNOLOGY

Long noncoding RNAs and human disease

(2011) Orly Wapinski et al.   TRENDS IN CELL BIOLOGY

Structural and Functional Differences in the Long Non-Coding RNA Hotair in Mouse and Human

(2011) Patrick Schorderet et al.   PLoS Genetics

The H19 locus: Role of an imprinted non-coding RNA in growth and development

(2010) Anne Gabory et al.   BIOESSAYS

Non-coding RNAs: Meet thy masters

(2010) Fabrício F. Costa   BIOESSAYS

Pseudogenes as an alternative source of natural antisense transcripts

(2010) Enrique M Muro et al.   BMC EVOLUTIONARY BIOLOGY

Maternally Expressed Gene 3, an Imprinted Noncoding RNA Gene, Is Associated with Meningioma Pathogenesis and Progression

(2010) X. Zhang et al.   CANCER RESEARCH

Recurrent Focal Copy-Number Changes and Loss of Heterozygosity Implicate Two Noncoding RNAs and One Tumor Suppressor Gene at Chromosome 3q13.31 in Osteosarcoma

(2010) I. Pasic et al.   CANCER RESEARCH

Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility

(2010) Suyoun Chung et al.   CANCER SCIENCE

Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis

(2010) Nobuyoshi Kosaka et al.   CANCER SCIENCE

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

(2010) Maite Huarte et al.   CELL

Serum microRNAs as a novel class of biomarkers: a comprehensive review of the literature

(2010) Nathalie Schöler et al.   EXPERIMENTAL HEMATOLOGY

The protein encoded by the functional steroid receptor RNA activator is a new modulator of ER alpha transcriptional activity

(2010) Shilpa Chooniedass-Kothari et al.   FEBS LETTERS

MALAT-1 enhances cell motility of lung adenocarcinoma cells by influencing the expression of motility-related genes

(2010) Keiko Tano et al.   FEBS LETTERS

Transcribed dark matter: meaning or myth?

(2010) C. P. Ponting et al.   HUMAN MOLECULAR GENETICS

Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers

(2010) Shinya Hayami et al.   INTERNATIONAL JOURNAL OF CANCER

Early detection of squamous cell lung cancer in sputum by a panel of microRNA markers

(2010) Lingxiao Xing et al.   MODERN PATHOLOGY

Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

(2010) Kyoko L. Yap et al.   MOLECULAR CELL

Genome-wide Identification of Polycomb-Associated RNAs by RIP-seq

(2010) Jing Zhao et al.   MOLECULAR CELL

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

(2010) Laura Poliseno et al.   NATURE

lncRNAdb: a reference database for long noncoding RNAs

(2010) Paulo P. Amaral et al.   NUCLEIC ACIDS RESEARCH

Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15 INK4B tumor suppressor gene

(2010) Y Kotake et al.   ONCOGENE

Mining Mammalian Transcript Data for Functional Long Non-Coding RNAs

(2010) Amit N. Khachane et al.   PLoS One

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

Noncoding RNA Gas5 Is a Growth Arrest- and Starvation-Associated Repressor of the Glucocorticoid Receptor

(2010) T. Kino et al.   Science Signaling

PRC2 Complexes with JARID2, MTF2, and esPRC2p48 in ES Cells to Modulate ES Cell Pluripotency and Somatic Cell Reprograming

(2010) Zhuo Zhang et al.   STEM CELLS

Polycomb group protein-mediated repression of transcription

(2010) Lluís Morey et al.   TRENDS IN BIOCHEMICAL SCIENCES

ncRAN, a Newly Identified Long Noncoding RNA, Enhances Human Bladder Tumor Growth, Invasion, and Survival

(2010) Yuyan Zhu et al.   UROLOGY

Most “Dark Matter” Transcripts Are Associated With Known Genes

(2010) Harm van Bakel et al.   PLOS BIOLOGY

A transcriptional sketch of a primary human breast cancer by 454 deep sequencing

(2009) Alessandro Guffanti et al.   BMC GENOMICS

A Susceptibility Locus for Papillary Thyroid Carcinoma on Chromosome 8q24

(2009) H. He et al.   CANCER RESEARCH

Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer

(2009) Wing Pui Tsang et al.   CARCINOGENESIS

Evolution and Functions of Long Noncoding RNAs

(2009) Chris P. Ponting et al.   CELL

Highly upregulated in liver cancer noncoding RNA is overexpressed in hepatic colorectal metastasis

(2009) Imad J. Matouk et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Long noncoding RNAs: functional surprises from the RNA world

(2009) J. E. Wilusz et al.   GENES & DEVELOPMENT

Non-coding RNAs: regulators of disease

(2009) Ryan J Taft et al.   JOURNAL OF PATHOLOGY

Altered miRNA expression in sputum for diagnosis of non-small cell lung cancer

(2009) Ying Xie et al.   LUNG CANCER

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

(2009) Mitchell Guttman et al.   NATURE

RNA-Directed Transcriptional Gene Silencing and Activation in Human Cells

(2009) Kevin V. Morris   OLIGONUCLEOTIDES

Misbehaviour of XIST RNA in Breast Cancer Cells

(2009) Silvia M. Sirchia et al.   PLoS One

UCA1, a non-protein-coding RNA up-regulated in bladder carcinoma and embryo, influencing cell growth and promoting invasion

(2008) Fan Wang et al.   FEBS LETTERS

Selective Loss ofMEG3Expression and Intergenic Differentially Methylated Region Hypermethylation in theMEG3/DLK1Locus in Human Clinically Nonfunctioning Pituitary Adenomas

(2008) Roger Gejman et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Roles of the EZH2 histone methyltransferase in cancer epigenetics

(2008) Jeffrey A. Simon et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

(2008) Wenqiang Yu et al.   NATURE

Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription

(2008) Xiangting Wang et al.   NATURE

GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer

(2008) M Mourtada-Maarabouni et al.   ONCOGENE

Bidirectional Transcription Directs Both Transcriptional Gene Activation and Suppression in Human Cells

(2008) Kevin V. Morris et al.   PLoS Genetics