Rodent Models of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis

Hyperresponsivity to Low-Dose Endotoxin during Progression to Nonalcoholic Steatohepatitis Is Regulated by Leptin-Mediated Signaling

(2012) Kento Imajo et al.   Cell Metabolism

High-fat, high-fructose diet induces hepatic iron overload via a hepcidin-independent mechanism prior to the onset of liver steatosis and insulin resistance in mice

(2012) Hiroyuki Tsuchiya et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Internalization of Modified Lipids by CD36 and SR-A Leads to Hepatic Inflammation and Lysosomal Cholesterol Storage in Kupffer Cells

(2012) Veerle Bieghs et al.   PLoS One

Melanocortin 4 Receptor–Deficient Mice as a Novel Mouse Model of Nonalcoholic Steatohepatitis

(2011) Michiko Itoh et al.   AMERICAN JOURNAL OF PATHOLOGY

Human Fatty Liver Disease: Old Questions and New Insights

(2011) J. C. Cohen et al.   SCIENCE

Insulin Resistance, Steatohepatitis, and Hepatocellular Carcinoma in a New Congenic Strain of Fatty Liver Shionogi (FLS) Mice with the Lepob Gene

(2010) Masahiko SOGA et al.   EXPERIMENTAL ANIMALS

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Pathophysiology of fatty acid oxidation disorders

(2010) M. J. Bennett   JOURNAL OF INHERITED METABOLIC DISEASE

Role of tumor necrosis factor α (TNFα) in the onset of fructose-induced nonalcoholic fatty liver disease in mice

(2010) Giridhar Kanuri et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Fructose and metabolic diseases: New findings, new questions

(2010) Luc Tappy et al.   NUTRITION

Toll-like receptor 4 is involved in the development of fructose-induced hepatic steatosis in mice

(2009) Astrid Spruss et al.   HEPATOLOGY

Severe NAFLD with hepatic necroinflammatory changes in mice fed trans fats and a high-fructose corn syrup equivalent

(2008) Laura H. Tetri et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Transition from Fatty Liver to NASH Associates with SAMe Depletion in db/db Mice Fed a Methionine Choline-Deficient Diet

(2008) Matthew Wortham et al.   DIGESTIVE DISEASES AND SCIENCES

Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice

(2008) Kun L. Ma et al.   HEPATOLOGY

Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: Role of endotoxin

(2008) Ina Bergheim et al.   JOURNAL OF HEPATOLOGY

Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet

(2008) Mary E. Rinella et al.   JOURNAL OF LIPID RESEARCH

Specific Physiological Roles for Signal Transducer and Activator of Transcription 3 in Leptin Receptor-Expressing Neurons

(2007) Merisa L. Piper et al.   MOLECULAR ENDOCRINOLOGY