Neuroprotective Effects of Psychotropic Drugs in Huntington’s Disease
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Neuroprotective Effects of Psychotropic Drugs in Huntington’s Disease
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 14, Issue 11, Pages 22558-22603
Publisher
MDPI AG
Online
2013-11-16
DOI
10.3390/ijms141122558
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Psychopharmacological Neuroprotection in Neurodegenerative Disease: Heuristic Clinical Applications
- (2014) Edward C. Lauterbach et al. JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES
- Psychopharmacological Neuroprotection in Neurodegenerative Disease: Assessing the Preclinical Data
- (2014) Edward C. Lauterbach et al. JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES
- Psychopharmacological Neuroprotection in Neurodegenerative Diseases, Part III: Criteria-Based Assessment: A Report of the ANPA Committee on Research
- (2014) Edward C. Lauterbach et al. JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES
- miR-196a Ameliorates Phenotypes of Huntington Disease in Cell, Transgenic Mouse, and Induced Pluripotent Stem Cell Models
- (2013) Pei-Hsun Cheng et al. AMERICAN JOURNAL OF HUMAN GENETICS
- MicroRNA-124 targets CCNA2 and regulates cell cycle in STHdhQ111/HdhQ111 cells
- (2013) Eashita Das et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Histone deacetylase class II and acetylated core histone immunohistochemistry in human brains with Huntington’s disease
- (2013) Hsin Hsien Yeh et al. BRAIN RESEARCH
- Mitochondrial Diseases of the Brain
- (2013) Rajnish K. Chaturvedi et al. FREE RADICAL BIOLOGY AND MEDICINE
- Regulation of Huntingtin Gene Expression by miRNA-137, -214, -148a, and Their Respective isomiRs
- (2013) Emilia Kozlowska et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington's disease
- (2013) Jing Jin et al. JOURNAL OF NEUROCHEMISTRY
- Genomic Landscape of Transcriptional and Epigenetic Dysregulation in Early Onset Polyglutamine Disease
- (2013) L. M. Valor et al. JOURNAL OF NEUROSCIENCE
- Antidepressants and mood stabilizers effects on histone deacetylase expression in C57BL/6 mice: Brain region specific changes
- (2013) Masanori Ookubo et al. JOURNAL OF PSYCHIATRIC RESEARCH
- Increased 5-Methylcytosine and Decreased 5-Hydroxymethylcytosine Levels are Associated with Reduced Striatal A2AR Levels in Huntington’s Disease
- (2013) Izaskun Villar-Menéndez et al. NEUROMOLECULAR MEDICINE
- Structural MRI in Huntington's disease and recommendations for its potential use in clinical trials
- (2013) Nellie Georgiou-Karistianis et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- MicroRNA-22 (miR-22) Overexpression Is Neuroprotective via General Anti-Apoptotic Effects and May also Target Specific Huntington’s Disease-Related Mechanisms
- (2013) Ana Jovicic et al. PLoS One
- Extensive changes in DNA methylation are associated with expression of mutant huntingtin
- (2013) C. W. Ng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Off label use of lithium in the treatment of Huntington′s disease: A case series
- (2013) Vijay Danivas et al. Indian Journal of Psychiatry
- Huntington's Disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads database
- (2012) Ravi Kiran Reddy Kalathur et al. BMC Neurology
- ATRX induction by mutant huntingtin via Cdx2 modulates heterochromatin condensation and pathology in Huntington's disease
- (2012) J Lee et al. CELL DEATH AND DIFFERENTIATION
- Neuroprotective effects of the mood stabilizer lamotrigine against glutamate excitotoxicity: roles of chromatin remodelling and Bcl-2 induction
- (2012) Yan Leng et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Therapeutic Effects of Valproate Combined With Lithium Carbonate on MPTP-Induced Parkinsonism in Mice: Possible Mediation Through Enhanced Autophagy
- (2012) Xue-zhong Li et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- trans-(−)-ϵ-Viniferin Increases Mitochondrial Sirtuin 3 (SIRT3), Activates AMP-activated Protein Kinase (AMPK), and Protects Cells in Models of Huntington Disease
- (2012) Jinrong Fu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Interrogation of brain miRNA and mRNA expression profiles reveals a molecular regulatory network that is perturbed by mutant huntingtin
- (2012) Jing Jin et al. JOURNAL OF NEUROCHEMISTRY
- Dysregulation of REST-regulated coding and non-coding RNAs in a cellular model of Huntington's disease
- (2012) Chiara Soldati et al. JOURNAL OF NEUROCHEMISTRY
- Selective G2/M arrest in a p53Val135-transformed cell line induced by lithium is mediated through an intricate network of MAPK and β-catenin signaling pathways
- (2012) Marco Man Kin Tsui et al. LIFE SCIENCES
- REST Is a Novel Prognostic Factor and Therapeutic Target for Medulloblastoma
- (2012) P. Taylor et al. MOLECULAR CANCER THERAPEUTICS
- eRNAs Are Required for p53-Dependent Enhancer Activity and Gene Transcription
- (2012) Carlos A. Melo et al. MOLECULAR CELL
- NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease
- (2012) Mahmoud A. Pouladi et al. NEUROBIOLOGY OF DISEASE
- Spatiotemporal mapping of brain atrophy in mouse models of Huntington's disease using longitudinal in vivo magnetic resonance imaging
- (2012) Manisha Aggarwal et al. NEUROIMAGE
- Mechanism(s) of Alteration of Micro RNA Expressions in Huntington’s Disease and Their Possible Contributions to the Observed Cellular and Molecular Dysfunctions in the Disease
- (2012) Mithun Sinha et al. NEUROMOLECULAR MEDICINE
- Psychotropic drug effects on gene transcriptomics relevant to Parkinson's disease
- (2012) Edward C. Lauterbach PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Psychotropics regulate Skp1a, Aldh1a1, and Hspa8 transcription — Potential to delay Parkinson's disease
- (2012) Edward C. Lauterbach PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Modulation of neuronal plasticity following chronic concomitant administration of the novel antipsychotic lurasidone with the mood stabilizer valproic acid
- (2012) F. Calabrese et al. PSYCHOPHARMACOLOGY
- PGC-1 Rescues Huntington's Disease Proteotoxicity by Preventing Oxidative Stress and Promoting TFEB Function
- (2012) T. Tsunemi et al. Science Translational Medicine
- The Sirtuin 2 Inhibitor AK-7 Is Neuroprotective in Huntington’s Disease Mouse Models
- (2012) Vanita Chopra et al. Cell Reports
- Psychotropic Drug Effects on Gene Transcriptomics Relevant to Alzheimer Disease
- (2011) Edward C. Lauterbach ALZHEIMER DISEASE & ASSOCIATED DISORDERS
- Mutant p53 protein localized in the cytoplasm inhibits autophagy
- (2011) Eugenia Morselli et al. CELL CYCLE
- Mitogen- and stress-activated protein kinase 1-induced neuroprotection in Huntington's disease: role on chromatin remodeling at the PGC-1-alpha promoter
- (2011) Elodie Martin et al. HUMAN MOLECULAR GENETICS
- Hsa-miR-34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington's disease
- (2011) Philip Michael Gaughwin et al. HUMAN MOLECULAR GENETICS
- The Melatonin MT1 Receptor Axis Modulates Mutant Huntingtin-Mediated Toxicity
- (2011) X. Wang et al. JOURNAL OF NEUROSCIENCE
- Histone deacetylase 1 is required for Carbamazepine-induced CYP3A4 expression
- (2011) Yin Wu et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Development of biomarkers for Huntington's disease
- (2011) David W Weir et al. LANCET NEUROLOGY
- Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data
- (2011) Sarah J Tabrizi et al. LANCET NEUROLOGY
- The Tricyclic Antidepressant Amitriptyline Inhibits D-Cyclin Transactivation and Induces Myeloma Cell Apoptosis by Inhibiting Histone Deacetylases: In Vitro and In Silico Evidence
- (2011) X. Mao et al. MOLECULAR PHARMACOLOGY
- Basal ganglia atrophy in prodromal Huntington's disease is detectable over one year using automated segmentation
- (2011) D.S. Adnan Majid et al. MOVEMENT DISORDERS
- Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets
- (2011) Mali Jiang et al. NATURE MEDICINE
- Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway
- (2011) Hyunkyung Jeong et al. NATURE MEDICINE
- Structural MRI detects progressive regional brain atrophy and neuroprotective effects in N171-82Q Huntington's disease mouse model
- (2011) Yong Cheng et al. NEUROIMAGE
- An Antisense CAG Repeat Transcript at JPH3 Locus Mediates Expanded Polyglutamine Protein Toxicity in Huntington's Disease-like 2 Mice
- (2011) Brian Wilburn et al. NEURON
- Combined Treatment with the Mood Stabilizers Lithium and Valproate Produces Multiple Beneficial Effects in Transgenic Mouse Models of Huntington's Disease
- (2011) Chi-Tso Chiu et al. NEUROPSYCHOPHARMACOLOGY
- Potential autophagy enhancers attenuate rotenone-induced toxicity in SH-SY5Y
- (2011) N. Xiong et al. NEUROSCIENCE
- Hippocampal-dependent antidepressant-like activity of histone deacetylase inhibition
- (2011) Herbert E. Covington et al. NEUROSCIENCE LETTERS
- Regulation of miR-146a by RelA/NFkB and p53 in STHdhQ111/HdhQ111 Cells, a Cell Model of Huntington's Disease
- (2011) Jayeeta Ghose et al. PLoS One
- Brain-Derived Neurotrophic Factor in Patients with Huntington's Disease
- (2011) Chiara Zuccato et al. PLoS One
- SAHA Decreases HDAC 2 and 4 Levels In Vivo and Improves Molecular Phenotypes in the R6/2 Mouse Model of Huntington's Disease
- (2011) Michal Mielcarek et al. PLoS One
- Transcriptional modulator H2A histone family, member Y (H2AFY) marks Huntington disease activity in man and mouse
- (2011) Y. Hu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Micro RNA -214,-150,-146a and-125b targetHuntingtingene
- (2011) Mithun Sinha et al. RNA Biology
- Neurodegenerative processes in Huntington's disease
- (2011) D Bano et al. Cell Death & Disease
- Nitric oxide mechanism in the protective effect of antidepressants against 3-nitropropionic acid-induced cognitive deficit, glutathione and mitochondrial alterations in animal model of Huntingtonʼs disease
- (2010) Puneet Kumar et al. BEHAVIOURAL PHARMACOLOGY
- Altered microRNAs in STHdhQ111/HdhQ111 cells: miR-146a targets TBP
- (2010) Mithun Sinha et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease
- (2010) Stephen J. McConoughey et al. EMBO Molecular Medicine
- Altered microRNA regulation in Huntington's disease models
- (2010) Soon-Tae Lee et al. EXPERIMENTAL NEUROLOGY
- Early atrophy of pallidum and accumbens nucleus in Huntington’s disease
- (2010) Simon J. A. Bogaard et al. JOURNAL OF NEUROLOGY
- Longitudinal change in regional brain volumes in prodromal Huntington disease
- (2010) E. H. Aylward et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Chronic Suppression of Phosphodiesterase 10A Alters Striatal Expression of Genes Responsible for Neurotransmitter Synthesis, Neurotransmission, and Signaling Pathways Implicated in Huntington's Disease
- (2010) R. J. Kleiman et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Novel protective mechanisms of antidepressants against 3-nitropropionic acid induced Huntington’s-like symptoms: a comparative study
- (2010) Puneet Kumar et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis
- (2010) Sarah J Tabrizi et al. LANCET NEUROLOGY
- Tetrabenazine is neuroprotective in Huntington's disease mice
- (2010) Hongyu Wang et al. Molecular Neurodegeneration
- A futility study of minocycline in Huntington's disease
- (2010) Merit Cudkowicz MOVEMENT DISORDERS
- The role of REST in transcriptional and epigenetic dysregulation in Huntington's disease
- (2010) Noel J. Buckley et al. NEUROBIOLOGY OF DISEASE
- A myriad of miRNA variants in control and Huntington’s disease brain regions detected by massively parallel sequencing
- (2010) Eulàlia Martí et al. NUCLEIC ACIDS RESEARCH
- Slowed progression in models of huntington disease by adipose stem cell transplantation
- (2009) Soon-Tae Lee et al. ANNALS OF NEUROLOGY
- Transcriptional dysregulation of coding and non-coding genes in cellular models of Huntington's disease
- (2009) Angela Bithell et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Evidence for an effect of clozapine on the regulation of fat-cell derived factors
- (2009) Zhi Yang et al. CLINICA CHIMICA ACTA
- Mouse models of Huntington disease: variations on a theme
- (2009) D. E. Ehrnhoefer et al. Disease Models & Mechanisms
- Inhibiting p53 pathways in microglia attenuates microglial-evoked neurotoxicity following exposure to Alzheimer peptides
- (2009) Christopher M. Davenport et al. JOURNAL OF NEUROCHEMISTRY
- Relationship between CAG repeat length and brain volume in premanifest and early Huntington’s disease
- (2009) S. M. D. Henley et al. JOURNAL OF NEUROLOGY
- The progression of regional atrophy in premanifest and early Huntington's disease: a longitudinal voxel-based morphometry study
- (2009) N. Z. Hobbs et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- The Bifunctional microRNA miR-9/miR-9* Regulates REST and CoREST and Is Downregulated in Huntington's Disease
- (2009) A. N. Packer et al. JOURNAL OF NEUROSCIENCE
- Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies
- (2009) Rocio G Urdinguio et al. LANCET NEUROLOGY
- Valproate ameliorates the survival and the motor performance in a transgenic mouse model of Huntington's disease
- (2009) Dénes Zádori et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Huntington's disease: the case for genetic modifiers
- (2009) James F Gusella et al. Genome Medicine
- Lithium-induced suppression of transcription repressor NRSF/REST: Effects on the dysfunction of neuronal differentiation by ethanol
- (2008) Takao Ishii et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II
- (2008) Alexandra Benchoua et al. HUMAN MOLECULAR GENETICS
- Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency
- (2008) Marc Roy et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Long-lasting depression-like behavior and epigenetic changes of BDNF gene expression induced by perinatal exposure to methylmercury
- (2008) Natalia Onishchenko et al. JOURNAL OF NEUROCHEMISTRY
- Altered Histone Monoubiquitylation Mediated by Mutant Huntingtin Induces Transcriptional Dysregulation
- (2008) M.-O. Kim et al. JOURNAL OF NEUROSCIENCE
- Regulation of autophagy by cytoplasmic p53
- (2008) Ezgi Tasdemir et al. NATURE CELL BIOLOGY
- Sertraline slows disease progression and increases neurogenesis in N171-82Q mouse model of Huntington's disease
- (2008) Wenzhen Duan et al. NEUROBIOLOGY OF DISEASE
- Evidence of calpain/cdk5 pathway inhibition by lithium in 3-nitropropionic acid toxicity in vivo and in vitro
- (2008) N. Crespo-Biel et al. NEUROPHARMACOLOGY
- Modulation of SIRT1 expression in different neurodegenerative models and human pathologies
- (2008) M. Pallàs et al. NEUROSCIENCE
- The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice
- (2008) E. A. Thomas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Possible role of sertraline against 3-nitropropionic acid induced behavioral, oxidative stress and mitochondrial dysfunctions in rat brain
- (2008) Puneet Kumar et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Chromosomal profiles of gene expression in Huntington's disease
- (2007) A. N. Anderson et al. BRAIN
- The antidepressant sertraline improves the phenotype, promotes neurogenesis and increases BDNF levels in the R6/2 Huntington's disease mouse model
- (2007) Qi Peng et al. EXPERIMENTAL NEUROLOGY
- Mitogen- and stress-activated protein kinase-1 deficiency is involved in expanded-huntingtin-induced transcriptional dysregulation and striatal death
- (2007) Emmanuel Roze et al. FASEB JOURNAL
- Longitudinal analysis of regional grey matter loss in Huntington disease: effects of the length of the expanded CAG repeat
- (2007) H H Ruocco et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Detection of Huntington's disease decades before diagnosis: the Predict-HD study
- (2007) J S Paulsen et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- A microRNA-based gene dysregulation pathway in Huntington's disease
- (2007) Rory Johnson et al. NEUROBIOLOGY OF DISEASE
- Haloperidol protects striatal neurons from dysfunction induced by mutated huntingtin in vivo
- (2007) Delphine Charvin et al. NEUROBIOLOGY OF DISEASE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now