Non-Coding RNAs and Cancer

Multiple neurofibromas as the presenting feature of familial atypical multiple malignant melanoma (FAMMM) syndrome

(2013) Rachel Vanneste et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Long non-coding RNA GAS5 regulates apoptosis in prostate cancer cell lines

(2013) M.R. Pickard et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Multiple roles for Piwi in silencing Drosophila transposons

(2013) N. V. Rozhkov et al.   GENES & DEVELOPMENT

Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state

(2013) A. Le Thomas et al.   GENES & DEVELOPMENT

The Heterochronic microRNA let-7 Inhibits Cell Motility by Regulating the Genes in the Actin Cytoskeleton Pathway in Breast Cancer

(2013) Xiaowen Hu et al.   MOLECULAR CANCER RESEARCH

MiR-34a/c-Dependent PDGFR-α/β Downregulation Inhibits Tumorigenesis and Enhances TRAIL-Induced Apoptosis in Lung Cancer

(2013) Michela Garofalo et al.   PLoS One

miR-200c Inhibits Melanoma Progression and Drug Resistance through Down-Regulation of Bmi-1

(2012) Shujing Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Coordinated Silencing of MYC-Mediated miR-29 by HDAC3 and EZH2 as a Therapeutic Target of Histone Modification in Aggressive B-Cell Lymphomas

(2012) Xinwei Zhang et al.   CANCER CELL

Cisplatin Sensitivity Mediated by WEE1 and CHK1 Is Mediated by miR-155 and the miR-15 Family

(2012) L. M. Pouliot et al.   CANCER RESEARCH

The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells

(2012) T. Gutschner et al.   CANCER RESEARCH

miR-15a and miR-16 affect the angiogenesis of multiple myeloma by targeting VEGF

(2012) Chun-Yan Sun et al.   CARCINOGENESIS

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

(2012) T. Derrien et al.   GENOME RESEARCH

eRNAs Are Required for p53-Dependent Enhancer Activity and Gene Transcription

(2012) Carlos A. Melo et al.   MOLECULAR CELL

Structure and function of Zucchini endoribonuclease in piRNA biogenesis

(2012) Hiroshi Nishimasu et al.   NATURE

Effect of miR-21 and miR-30b/c on TRAIL-induced apoptosis in glioma cells

(2012) C Quintavalle et al.   ONCOGENE

MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

(2012) M. Fabbri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of piRNAs in Hela cells by massive parallel sequencing

(2011) Yilu Lu et al.   BMB Reports

The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis

(2011) H E Gee et al.   BRITISH JOURNAL OF CANCER

HIWI is associated with prognosis in patients with hepatocellular carcinoma after curative resection

(2011) Yi-Ming Zhao et al.   CANCER

piR-823, a novel non-coding small RNA, demonstrates in vitro and in vivo tumor suppressive activity in human gastric cancer cells

(2011) Jia Cheng et al.   CANCER LETTERS

No-Nonsense Functions for Long Noncoding RNAs

(2011) Takashi Nagano et al.   CELL

piRNA, the new non-coding RNA, is aberrantly expressed in human cancer cells

(2011) Jia Cheng et al.   CLINICA CHIMICA ACTA

Detection of circulating tumor cells in peripheral blood from patients with gastric cancer using piRNAs as markers

(2011) Long Cui et al.   CLINICAL BIOCHEMISTRY

Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

(2011) M. N. Cabili et al.   GENES & DEVELOPMENT

CpG island methylation status of miRNAs in esophageal squamous cell carcinoma

(2011) Xuedan Chen et al.   INTERNATIONAL JOURNAL OF CANCER

Progressive miRNA expression profiles in cervical carcinogenesis and identification of HPV-related target genes for miR-29

(2011) Yang Li et al.   JOURNAL OF PATHOLOGY

Liposomal Delivery of MicroRNA-7-Expressing Plasmid Overcomes Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor-Resistance in Lung Cancer Cells

(2011) K. Rai et al.   MOLECULAR CANCER THERAPEUTICS

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

(2011) John R Prensner et al.   NATURE BIOTECHNOLOGY

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

(2011) Tiffany Hung et al.   NATURE GENETICS

Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control

(2011) Jeannie T. Lee   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Silencing microRNA by interfering nanoparticles in mice

(2011) Jie Su et al.   NUCLEIC ACIDS RESEARCH

Widespread expression of piRNA-like molecules in somatic tissues

(2011) Zheng Yan et al.   NUCLEIC ACIDS RESEARCH

Small nucleolar RNA 42 acts as an oncogene in lung tumorigenesis

(2011) Y-P Mei et al.   ONCOGENE

miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTPμ

(2011) C Quintavalle et al.   ONCOGENE

Identification of piRNAs in the central nervous system

(2011) E. J. Lee et al.   RNA

Long noncoding RNAs in cell biology

(2011) Michael B. Clark et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Expression of PSCA, PIWIL1 and TBX2 and its correlation with HPV16 infection in formalin-fixed, paraffin-embedded cervical squamous cell carcinoma specimens

(2010) Wen-Kang Liu et al.   ARCHIVES OF VIROLOGY

Clinical significance of Hiwi gene expression in gliomas

(2010) Guan Sun et al.   BRAIN RESEARCH

MicroRNA-155 Functions as an OncomiR in Breast Cancer by Targeting the Suppressor of Cytokine Signaling 1 Gene

(2010) S. Jiang et al.   CANCER RESEARCH

Development of a Lung Cancer Therapeutic Based on the Tumor Suppressor MicroRNA-34

(2010) J. F. Wiggins et al.   CANCER RESEARCH

Long Noncoding RNAs with Enhancer-like Function in Human Cells

(2010) Ulf Andersson Ørom et al.   CELL

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

(2010) Maite Huarte et al.   CELL

Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer

(2010) Dmitri Lodygin et al.   CELL CYCLE

MicroRNA-21 (miR-21) represses tumor suppressor PTEN and promotes growth and invasion in non-small cell lung cancer (NSCLC)

(2010) Ji-guang Zhang et al.   CLINICA CHIMICA ACTA

Frequent Downregulation of miR-34 Family in Human Ovarian Cancers

(2010) D. C. Corney et al.   CLINICAL CANCER RESEARCH

Decoding the function of nuclear long non-coding RNAs

(2010) Ling-Ling Chen et al.   CURRENT OPINION IN CELL BIOLOGY

Roles for the Yb body components Armitage and Yb in primary piRNA biogenesis in Drosophila

(2010) K. Saito et al.   GENES & DEVELOPMENT

Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3

(2010) Yu Wang et al.   JOURNAL OF HEPATOLOGY

MicroRNA Cluster 221-222 and Estrogen Receptor α Interactions in Breast Cancer

(2010) Gianpiero Di Leva et al.   JNCI-Journal of the National Cancer Institute

Small nucleolar RNA signatures as biomarkers for non-small-cell lung cancer

(2010) Jipei Liao et al.   Molecular Cancer

Negative Regulation of Tumor Suppressor p53 by MicroRNA miR-504

(2010) Wenwei Hu et al.   MOLECULAR CELL

Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

(2010) Kyoko L. Yap et al.   MOLECULAR CELL

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

(2010) Laura Poliseno et al.   NATURE

Human box C/D snoRNAs with miRNA like functions: expanding the range of regulatory RNAs

(2010) Markus Brameier et al.   NUCLEIC ACIDS RESEARCH

lncRNAdb: a reference database for long noncoding RNAs

(2010) Paulo P. Amaral et al.   NUCLEIC ACIDS RESEARCH

Expression of PSCA, PIWIL1, and TBX2 in Endometrial Adenocarcinoma

(2010) Wen-Kang Liu et al.   ONKOLOGIE

Noncoding RNA Gas5 Is a Growth Arrest- and Starvation-Associated Repressor of the Glucocorticoid Receptor

(2010) T. Kino et al.   Science Signaling

The piRNA pathway: a fly's perspective on the guardian of the genome

(2010) Kirsten-André Senti et al.   TRENDS IN GENETICS

RNA regulation of epigenetic processes

(2009) John S. Mattick et al.   BIOESSAYS

Expression of HIWI in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis

(2009) Wei He et al.   BMC CANCER

miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation

(2009) Michela Garofalo et al.   CANCER CELL

MiR-15a and MiR-16 Control Bmi-1 Expression in Ovarian Cancer

(2009) R. Bhattacharya et al.   CANCER RESEARCH

Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

(2009) Janaiah Kota et al.   CELL

Evolution and Functions of Long Noncoding RNAs

(2009) Chris P. Ponting et al.   CELL

The long and the short of noncoding RNAs

(2009) Christopher A Brosnan et al.   CURRENT OPINION IN CELL BIOLOGY

The microRNA miR-92 increases proliferation of myeloid cells and by targeting p63 modulates the abundance of its isoforms

(2009) Isabella Manni et al.   FASEB JOURNAL

A natural antisense transcript, BOKAS, regulates the pro-apoptotic activity of human Bok

(2009) Zhang   INTERNATIONAL JOURNAL OF ONCOLOGY

miR-34a, miR-29c and miR-17-5p are downregulated in CLL patients with TP53 abnormalities

(2009) M Mraz et al.   LEUKEMIA

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

(2009) Mitchell Guttman et al.   NATURE

Long non-coding RNAs: insights into functions

(2009) Tim R. Mercer et al.   NATURE REVIEWS GENETICS

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

(2009) Ahmad M. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia

(2008) R. Garzon et al.   BLOOD

The stem cell-associated Hiwi gene in human adenocarcinoma of the pancreas: expression and risk of tumour-related death

(2008) L F Grochola et al.   BRITISH JOURNAL OF CANCER

E2F1-Regulated MicroRNAs Impair TGFβ-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer

(2008) Fabio Petrocca et al.   CANCER CELL

The GAS5 (growth arrest-specific transcript 5) gene fuses to BCL6 as a result of t(1;3)(q25;q27) in a patient with B-cell lymphoma

(2008) Yuichi Nakamura et al.   CANCER GENETICS AND CYTOGENETICS

MicroRNAs

(2008) Muller Fabbri et al.   CANCER JOURNAL

miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells

(2008) Na Li et al.   CANCER LETTERS

The Promyelocytic Leukemia Zinc Finger-MicroRNA-221/-222 Pathway Controls Melanoma Progression through Multiple Oncogenic Mechanisms

(2008) F. Felicetti et al.   CANCER RESEARCH

Zili is required for germ cell differentiation and meiosis in zebrafish

(2008) Saskia Houwing et al.   EMBO JOURNAL

A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition

(2008) M. Beltran et al.   GENES & DEVELOPMENT

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

(2008) S.-M. Park et al.   GENES & DEVELOPMENT

Growth arrest in human T-cells is controlled by the non-coding RNA growth-arrest-specific transcript 5 (GAS5)

(2008) M. Mourtada-Maarabouni et al.   JOURNAL OF CELL SCIENCE

Noncoding RNA in development

(2008) Paulo P. Amaral et al.   MAMMALIAN GENOME

Translational Control by a Small RNA: Dendritic BC1 RNA Targets the Eukaryotic Initiation Factor 4A Helicase Mechanism

(2008) D. Lin et al.   MOLECULAR AND CELLULAR BIOLOGY

Piwi and piRNAs Act Upstream of an Endogenous siRNA Pathway to Suppress Tc3 Transposon Mobility in the Caenorhabditis elegans Germline

(2008) Partha P. Das et al.   MOLECULAR CELL

Kcnq1ot1 Antisense Noncoding RNA Mediates Lineage-Specific Transcriptional Silencing through Chromatin-Level Regulation

(2008) Radha Raman Pandey et al.   MOLECULAR CELL

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

(2008) Wenqiang Yu et al.   NATURE

Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription

(2008) Xiangting Wang et al.   NATURE

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

(2008) Désirée Bonci et al.   NATURE MEDICINE

Antisense transcripts are targets for activating small RNAs

(2008) Jacob C Schwartz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

NRED: a database of long noncoding RNA expression

(2008) Marcel E. Dinger et al.   NUCLEIC ACIDS RESEARCH

MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer

(2008) M Garofalo et al.   ONCOGENE

GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer

(2008) M Mourtada-Maarabouni et al.   ONCOGENE

MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma

(2008) F Fornari et al.   ONCOGENE

MiR-15a and miR-16-1 cluster functions in human leukemia

(2008) George A. Calin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide search for yeast RNase P substrates reveals role in maturation of intron-encoded box C/D small nucleolar RNAs

(2008) D. J. Coughlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Air Noncoding RNA Epigenetically Silences Transcription by Targeting G9a to Chromatin

(2008) T. Nagano et al.   SCIENCE

Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome

(2008) J. Zhao et al.   SCIENCE

Bidirectional Transcription Directs Both Transcriptional Gene Activation and Suppression in Human Cells

(2008) Kevin V. Morris et al.   PLoS Genetics