Homology Models of Melatonin Receptors: Challenges and Recent Advances

Loop prediction for a GPCR homology model: Algorithms and results

(2013) Dahlia A. Goldfeld et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

MT1-Selective Melatonin Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Dynamics Investigation ofN-{[(3-O-Substituted)anilino]alkyl}amides

(2012) Silvia Rivara et al.   ChemMedChem

Recent Progress in the Development of Agonists and Antagonists for Melatonin Receptors

(2012) D. P. Zlotos   CURRENT MEDICINAL CHEMISTRY

Current Assessment of Docking into GPCR Crystal Structures and Homology Models: Successes, Challenges, and Guidelines

(2012) Thijs Beuming et al.   Journal of Chemical Information and Modeling

Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

(2012) W. Liu et al.   SCIENCE

Application of the bridgehead fragments for the design of conformationally restricted melatonin analogues

(2011) Olga N. Zefirova et al.   BIOORGANIC CHEMISTRY

Showcasing modern molecular dynamics simulations of membrane proteins through G protein-coupled receptors

(2011) Jennifer M Johnston et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Identification of Essential Cannabinoid-binding Domains

(2011) Joong-Youn Shim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Promotion of Non-Rapid Eye Movement Sleep and Activation of Reticular Thalamic Neurons by a Novel MT2 Melatonin Receptor Ligand

(2011) R. Ochoa-Sanchez et al.   JOURNAL OF NEUROSCIENCE

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

(2011) Søren G. F. Rasmussen et al.   NATURE

Successful prediction of the intra- and extracellular loops of four G-protein-coupled receptors

(2011) D. A. Goldfeld et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Status of GPCR Modeling and Docking as Reflected by Community-wide GPCR Dock 2010 Assessment

(2011) Irina Kufareva et al.   STRUCTURE

Diversity and modularity of G protein-coupled receptor structures

(2011) Vsevolod Katritch et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Melatonin Receptor Agonists: New Options for Insomnia and Depression Treatment

(2010) Gilberto Spadoni et al.   CNS Neuroscience & Therapeutics

Clinical Uses of Melatonin: Evaluation of Human Trials

(2010) E.J. Sanchez-Barcelo et al.   CURRENT MEDICINAL CHEMISTRY

Ligand Binding and Subtype Selectivity of the Human A2AAdenosine Receptor

(2010) Veli-Pekka Jaakola et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, Classification, and Pharmacology of G Protein-Coupled Melatonin Receptors

(2010) M. L. Dubocovich et al.   PHARMACOLOGICAL REVIEWS

Design and synthesis of 3-phenyltetrahydronaphthalenic derivatives as new selective MT2 melatoninergic ligands. Part II

(2009) Sophie Durieux et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Evaluation of Homology Modeling of G-Protein-Coupled Receptors in Light of the A2AAdenosine Receptor Crystallographic Structure

(2009) Andrei A. Ivanov et al.   JOURNAL OF MEDICINAL CHEMISTRY

Revisiting Automated G-Protein Coupled Receptor Modeling: The Benefit of Additional Template Structures for a Neurokinin-1 Receptor Model

(2009) Benny Kneissl et al.   JOURNAL OF MEDICINAL CHEMISTRY

Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008

(2009) Mayako Michino et al.   NATURE REVIEWS DRUG DISCOVERY

A Single Conserved Leucine Residue on the First Intracellular Loop Regulates ER Export of G Protein-Coupled Receptors

(2009) Matthew T. Duvernay et al.   TRAFFIC

Melatonin Receptor Agonists: SAR and Applications to the Treatment of Sleep-Wake Disorders

(2008) Silvia Rivara et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Homology modeling of MT1 and MT2 receptors

(2008) Amaury Farce et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The role of proline residues in the structure and function of human MT2 melatonin receptor

(2008) Petr Mazna et al.   JOURNAL OF PINEAL RESEARCH

Crystal structure of opsin in its G-protein-interacting conformation

(2008) Patrick Scheerer et al.   NATURE

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

(2008) Valeriya Lyssenko et al.   NATURE GENETICS

Physiological effects of melatonin: Role of melatonin receptors and signal transduction pathways

(2008) S PANDIPERUMAL et al.   PROGRESS IN NEUROBIOLOGY