Impaired Pre-mRNA Processing and Altered Architecture of 3' Untranslated Regions Contribute to the Development of Human Disorders

Polymorphisms within theCOL5A13′-UTR That Alters mRNA Structure and theMIR608Gene are Associated with Achilles Tendinopathy

(2013) Yoonus Abrahams et al.   ANNALS OF HUMAN GENETICS

Single nucleotide variation in the TP53 3' untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: a report from the International DLBCL Rituximab-CHOP Consortium Program

(2013) Y. Li et al.   BLOOD

Low penetrance susceptibility to glioma is caused by the TP53 variant rs78378222

(2013) V Enciso-Mora et al.   BRITISH JOURNAL OF CANCER

Alternative cleavage and polyadenylation: the long and short of it

(2013) Bin Tian et al.   TRENDS IN BIOCHEMICAL SCIENCES

Molecular Genetics and Genetic Testing in Myotonic Dystrophy Type 1

(2013) Dušanka Savić Pavićević et al.   Biomed Research International

The Poly(A)-Binding Protein Nuclear 1 Suppresses Alternative Cleavage and Polyadenylation Sites

(2012) Mathias Jenal et al.   CELL

Expression of the polyalanine expansion mutant of nuclear poly(A)-binding protein induces apoptosis via the p53 pathway

(2012) Rumpa Biswas Bhattacharjee et al.   CELL BIOLOGY INTERNATIONAL

Best practice guidelines and recommendations on the molecular diagnosis of myotonic dystrophy types 1 and 2

(2012) Erik-Jan Kamsteeg et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

A functional germline variant in the P53 polyadenylation signal and risk of esophageal squamous cell carcinoma

(2012) Liqing Zhou et al.   GENE

GSK3β mediates muscle pathology in myotonic dystrophy

(2012) Karlie Jones et al.   JOURNAL OF CLINICAL INVESTIGATION

Huntington disease-like 2 (HDL2) in Venezuela: frequency and ethnic origin

(2012) Irene Paradisi et al.   JOURNAL OF HUMAN GENETICS

Estrogen-induced upregulation and 3′-UTR shortening of CDC6

(2012) Begum H. Akman et al.   NUCLEIC ACIDS RESEARCH

Poly(A) binding protein nuclear 1 levels affect alternative polyadenylation

(2012) Eleonora de Klerk et al.   NUCLEIC ACIDS RESEARCH

Shortening of 3′UTRs Correlates with Poor Prognosis in Breast and Lung Cancer

(2012) Antonio Lembo et al.   PLoS One

MicroRNA-mediated regulation of gene expression is affected by disease-associated SNPs within the 3′-UTR via altered RNA structure

(2012) Ulrike Haas et al.   RNA Biology

The role of the 3' untranslated region in post-transcriptional regulation of protein expression in mammalian cells.

(2012) Eva Matoulkova et al.   RNA Biology

Loss of junctophilin-3 contributes to huntington disease-like 2 pathogenesis

(2011) Ana I. Seixas et al.   ANNALS OF NEUROLOGY

Differential genome-wide profiling of tandem 3' UTRs among human breast cancer and normal cells by high-throughput sequencing

(2011) Y. Fu et al.   GENOME RESEARCH

Hb S-β-Thalassemia: Molecular, Hematological and Clinical Comparisons

(2011) Graham R. Serjeant et al.   HEMOGLOBIN

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

(2011) Simon N Stacey et al.   NATURE GENETICS

An Antisense CAG Repeat Transcript at JPH3 Locus Mediates Expanded Polyglutamine Protein Toxicity in Huntington's Disease-like 2 Mice

(2011) Brian Wilburn et al.   NEURON

CAG repeats mimic CUG repeats in the misregulation of alternative splicing

(2011) Agnieszka Mykowska et al.   NUCLEIC ACIDS RESEARCH

Complex and dynamic landscape of RNA polyadenylation revealed by PAS-Seq

(2011) P. J. Shepard et al.   RNA

Comprehensive Polyadenylation Site Maps in Yeast and Human Reveal Pervasive Alternative Polyadenylation

(2010) Fatih Ozsolak et al.   CELL

Crossing the borders: Poly(A)-binding proteins working on both sides of the fence

(2010) Jean-François Lemay et al.   RNA Biology

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development

(2009) Z. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ectopic expression of cyclin D3 corrects differentiation of DM1 myoblasts through activation of RNA CUG-binding protein, CUGBP1

(2008) Elizabeth Salisbury et al.   EXPERIMENTAL CELL RESEARCH

Polymorphisms in p53 and the p53 pathway: roles in cancer susceptibility and response to treatment

(2008) Roman Hrstka et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

(2008) R. Sandberg et al.   SCIENCE