Recent Advances on the Neuroprotective Potential of Antioxidants in Experimental Models of Parkinson’s Disease

An in-silico strategy to explore neuroprotection by quercetin in cerebral ischemia: A novel hypothesis based on inhibition of matrix metalloproteinase (MMPs) and acid sensing ion channel 1a (ASIC1a)

(2012) Anand Kumar Pandey et al.   MEDICAL HYPOTHESES

Evaluation of the Neurotoxic/Neuroprotective Role of Organoselenides Using Differentiated Human Neuroblastoma SH-SY5Y Cell Line Challenged with 6-Hydroxydopamine

(2012) Fernanda Martins Lopes et al.   NEUROTOXICITY RESEARCH

Chronic dietary supplementation with turmeric protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-mediated neurotoxicity in vivo: implications for Parkinson's disease

(2011) Rajeswara Babu Mythri et al.   BRITISH JOURNAL OF NUTRITION

Ethanolic Extract of Fructus Alpinia oxyphylla Protects Against 6-Hydroxydopamine-Induced Damage of PC12 Cells In Vitro and Dopaminergic Neurons in Zebrafish

(2011) Zai-Jun Zhang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Protective effect of resveratrol derived from Polygonum cuspidatum and its liposomal form on nigral cells in Parkinsonian rats

(2011) Yanchun Wang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Neuroprotective Effects of 3α-Acetoxyeudesma-1,4(15),11(13)-trien-12,6α-olide Against Dopamine-Induced Apoptosis in the Human Neuroblastoma SH-SY5Y Cell Line

(2011) Uk Koo et al.   NEUROCHEMICAL RESEARCH

Curcumin protects against A53T alpha-synuclein-induced toxicity in a PC12 inducible cell model for Parkinsonism

(2011) Zhaohui Liu et al.   PHARMACOLOGICAL RESEARCH

Idebenone and Resveratrol Extend Lifespan and Improve Motor Function of HtrA2 Knockout Mice

(2011) Ellen Gerhardt et al.   PLoS One

Brassinosteroids and analogs as neuroprotectors: Synthesis and structure–activity relationships

(2011) Jihane Ismaili et al.   STEROIDS

Deprenyl prevents MPP+-induced oxidative damage in PC12 cells by the upregulation of Nrf2-mediated NQO1 expression through the activation of PI3K/Akt and Erk

(2011) Haibing Xiao et al.   TOXICOLOGY

Mitochondrial Approaches for Neuroprotection

(2010) Rajnish K. Chaturvedi et al.   Annals of the New York Academy of Sciences

Oxidative Stress in Parkinson's Disease

(2010) Chun Zhou et al.   Annals of the New York Academy of Sciences

Rosmarinic Acid Antagonized 1-Methyl-4-Phenylpyridinium (MPP+)-Induced Neurotoxicity in MES23.5 Dopaminergic Cells

(2010) Tingting Du et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Proanthocyanidin-rich fraction from Croton celtidifolius Baill confers neuroprotection in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine rat model of Parkinson’s disease

(2010) Eduardo L. G. Moreira et al.   JOURNAL OF NEURAL TRANSMISSION

Antioxidant Properties of Bromocriptine, a Dopamine Agonist

(2010) Toshikazu Yoshikawa et al.   JOURNAL OF NEUROCHEMISTRY

S-Allylcysteine, a garlic compound, protects against oxidative stress in 1-methyl-4-phenylpyridinium-induced parkinsonism in mice

(2010) Patricia Rojas et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Luteolin from Purple Perilla mitigates ROS insult particularly in primary neurons

(2010) Gang Zhao et al.   NEUROBIOLOGY OF AGING

Phenothiazines interfere with dopaminergic neurodegeneration in Caenorhabditis elegans models of Parkinson's disease

(2010) Justyna B. Mocko et al.   NEUROBIOLOGY OF DISEASE

Neuroprotective effects of SCM198 on 6-hydroxydopamine-induced behavioral deficit in rats and cytotoxicity in neuronal SH-SY5Y cells

(2010) Xue Ru Shi et al.   NEUROCHEMISTRY INTERNATIONAL

dl-3-n-Butylphthalide prevents oxidative damage and reduces mitochondrial dysfunction in an MPP+-induced cellular model of Parkinson's disease

(2010) Jin-zhong Huang et al.   NEUROSCIENCE LETTERS

Oral N-Acetyl-Cysteine Attenuates Loss of Dopaminergic Terminals in α-Synuclein Overexpressing Mice

(2010) Joanne Clark et al.   PLoS One

Leonurine Protects Middle Cerebral Artery Occluded Rats Through Antioxidant Effect and Regulation of Mitochondrial Function

(2010) Kok Poh Loh et al.   STROKE

Mitochondria Targeted Peptides Protect Against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Neurotoxicity

(2009) Lichuan Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

Quercetin Inhibit Human SW480 Colon Cancer Growth in Association with Inhibition of Cyclin D1and Survivin Expression through Wnt/β-Catenin Signaling Pathway

(2009) Bao-En Shan et al.   CANCER INVESTIGATION

Coenzyme Q10 in Neuromuscular and Neurodegenerative Disorders

(2009) M. Mancuso et al.   CURRENT DRUG TARGETS

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

(2009) Bayani Uttara et al.   Current Neuropharmacology

Toxico-pathological changes induced by cypermethrin in broiler chicks: Their attenuation with Vitamin E and selenium

(2009) Faiza Aslam et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Cerebral protection of purified Herba Leonuri extract on middle cerebral artery occluded rats

(2009) Kok Poh Loh et al.   JOURNAL OF ETHNOPHARMACOLOGY

Novel imine antioxidants at low nanomolar concentrations protect dopaminergic cells from oxidative neurotoxicity

(2009) Parvana Hajieva et al.   JOURNAL OF NEUROCHEMISTRY

Combination therapy with Coenzyme Q10and creatine produces additive neuroprotective effects in models of Parkinson’s and Huntington’s Diseases

(2009) Lichuan Yang et al.   JOURNAL OF NEUROCHEMISTRY

 -Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate via c-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin

(2009) Q.-L. Ma et al.   JOURNAL OF NEUROSCIENCE

Acute Treatment with Diphenyl Diselenide Inhibits Glutamate Uptake into Rat Hippocampal Slices and Modifies Glutamate Transporters, SNAP-25, and GFAP Immunocontent

(2009) Ana P. Ardais et al.   TOXICOLOGICAL SCIENCES

Effects of 28-homobrassinolide on growth, lipid peroxidation and antioxidative enzyme activities in seedlings of Zea mays L. under salinity stress

(2008) Nitika Arora et al.   ACTA PHYSIOLOGIAE PLANTARUM

Mitochondrial dysfunction in the limelight of Parkinson's disease pathogenesis

(2008) Rebecca Banerjee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Protective effects of SUN N8075, a novel agent with antioxidant properties, in in vitro and in vivo models of Parkinson's disease

(2008) A. Oyagi et al.   BRAIN RESEARCH

Diphenyl diselenide confers neuroprotection against hydrogen peroxide toxicity in hippocampal slices

(2008) Thaís Posser et al.   BRAIN RESEARCH

PROTECTIVE EFFECTS OF LEONURINE IN NEONATAL RAT HYPOXIC CARDIOMYOCYTES AND RAT INFARCTED HEART

(2008) Xin-Hua Liu et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

NP7 protects from cell death induced by oxidative stress in neuronal and glial midbrain cultures from parkin null mice

(2008) M.A. Mena et al.   FEBS LETTERS

Combined R-α-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson’s disease

(2008) Hongyu Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mitochondria in the aetiology and pathogenesis of Parkinson's disease

(2008) Anthony HV Schapira   LANCET NEUROLOGY

The clinical relevance of levodopa toxicity in the treatment of Parkinson's disease

(2008) Anthony H.V. Schapira   MOVEMENT DISORDERS

Grape seed polyphenols and curcumin reduce genomic instability events in a transgenic mouse model for Alzheimer's disease

(2008) Philip Thomas et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Bromocriptine activates NQO1 via Nrf2-PI3K/Akt signaling: Novel cytoprotective mechanism against oxidative damage

(2008) Ju Hee Lim et al.   PHARMACOLOGICAL RESEARCH

Inhibition of monoamine oxidase-B by the polyphenolic compound, curcumin and its metabolite tetrahydrocurcumin, in a model of Parkinson’s disease induced by MPTP neurodegeneration in mice

(2008) A. Rajeswari et al.   INFLAMMOPHARMACOLOGY

Curcumin as “Curecumin”: From kitchen to clinic

(2007) Ajay Goel et al.   BIOCHEMICAL PHARMACOLOGY

A role for brassinosteroids in the amelioration of aluminium stress through antioxidant system in mung bean (Vigna radiata L. Wilczek)

(2007) B. Ali et al.   ENVIRONMENTAL AND EXPERIMENTAL BOTANY

Curcumin treatment alleviates the effects of glutathione depletion in vitro and in vivo: Therapeutic implications for Parkinson's disease explained via in silico studies

(2007) Balusamy Jagatha et al.   FREE RADICAL BIOLOGY AND MEDICINE