Targeting Protective Autophagy Exacerbates UV-Triggered Apoptotic Cell Death

Compensatory mechanisms and the type of injury determine the fate of cells with impaired macroautophagy

(2014) Rajat Singh et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

ATRcontrols the p21WAF1/Cip1protein up-regulation and apoptosis in response to low UV fluences

(2011) Huda H. Al-Khalaf et al.   MOLECULAR CARCINOGENESIS

Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway

(2010) Li-Hsin Chen et al.   BIOCHEMICAL PHARMACOLOGY

Sensitization to radiation-induced DNA damage accelerates loss of bcl-2 and increases apoptosis and autophagy

(2010) Manuel Rieber et al.   CANCER BIOLOGY & THERAPY

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

(2010) A. Alexander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mouse models for ATR deficiency

(2009) Mark O’Driscoll   DNA REPAIR

ATR–Chk1 Pathway Inhibition Promotes Apoptosis after UV Treatment in Primary Human Keratinocytes: Potential Basis for the UV Protective Effects of Caffeine

(2009) Timothy P. Heffernan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

G-quadruplex ligand SYUIQ-5 induces autophagy by telomere damage and TRF2 delocalization in cancer cells

(2009) W.-J. Zhou et al.   MOLECULAR CANCER THERAPEUTICS

Life, death and burial: multifaceted impact of autophagy

(2008) Lorenzo Galluzzi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

To Die or Not to Die: That is the Autophagic Question

(2008) Maria Maiuri et al.   CURRENT MOLECULAR MEDICINE

Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells

(2008) Sudharsan Periyasamy-Thandavan et al.   KIDNEY INTERNATIONAL

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY