A novel NKX2-5 loss-of-function mutation predisposes to familial dilated cardiomyopathy and arrhythmias

GATA5 loss-of-function mutations associated with congenital bicuspid aortic valve

(2014) LIN-MEI SHI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Nucleocytoplasmic Shuttling of a GATA Transcription Factor Functions as a Development Timer

(2014) H. Cai et al.   SCIENCE

Mutation spectrum of GATA4 associated with congenital atrial septal defects

(2013) Yi-Qing Yang et al.   Archives of Medical Science

GATA4 loss-of-function mutation underlies familial dilated cardiomyopathy

(2013) Ruo-Gu Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Genetics in dilated cardiomyopathy

(2013) Pablo Garcia-Pavia et al.   Biomarkers in Medicine

Functional Characterization of a Novel Mutation in NKX2-5 Associated With Congenital Heart Disease and Adult-Onset Cardiomyopathy

(2013) Mauro W. Costa et al.   Circulation-Cardiovascular Genetics

Prevalence and spectrum of Nkx2.5 mutations associated with idiopathic atrial fibrillation

(2013) WH Xie et al.   Clinics

Two novel and functional DNA sequence variants within an upstream enhancer of the human NKX2-5 gene in ventricular septal defects

(2013) Wenhui Huang et al.   GENE

GATA4 Loss-of-Function Mutations Underlie Familial Tetralogy of Fallot

(2013) Yi-Qing Yang et al.   HUMAN MUTATION

GATA5 loss-of-Function Mutations Underlie Tetralogy of Fallot

(2013) Dong Wei et al.   International Journal of Medical Sciences

A novel GATA4 loss-of-function mutation responsible for familial dilated cardiomyopathy

(2013) LAN ZHAO et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Genetic mutations and mechanisms in dilated cardiomyopathy

(2013) Elizabeth M. McNally et al.   JOURNAL OF CLINICAL INVESTIGATION

Lrrc10 is a novel cardiac-specific target gene of Nkx2-5 and GATA4

(2013) Matthew J. Brody et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Dilated cardiomyopathy: the complexity of a diverse genetic architecture

(2013) Ray E. Hershberger et al.   Nature Reviews Cardiology

Mitochondrial Fusion Directs Cardiomyocyte Differentiation via Calcineurin and Notch Signaling

(2013) A. Kasahara et al.   SCIENCE

Wenckebach Periodicity at Rest That Normalizes With Tachycardia in a Family With a NKX2.5 Mutation

(2012) Warren Guntheroth et al.   AMERICAN JOURNAL OF CARDIOLOGY

Contribution of Global Rare Copy-Number Variants to the Risk of Sporadic Congenital Heart Disease

(2012) Rachel Soemedi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Novel GATA5 loss-of-function mutations underlie familial atrial fibrillation

(2012) JY Gu et al.   Clinics

Novel GATA6 Mutations Associated with Congenital Ventricular Septal Defect or Tetralogy of Fallot

(2012) Juan Wang et al.   DNA AND CELL BIOLOGY

Phenotypic heterogeneity in a family with a small atypical microduplication of chromosome 22q11.2 involving TBX1

(2012) James D. Weisfeld-Adams et al.   European Journal of Medical Genetics

GATA6 loss-of-function mutation in atrial fibrillation

(2012) Yi-Qing Yang et al.   European Journal of Medical Genetics

Genetic analysis of an enhancer of the NKX2-5 gene in ventricular septal defects

(2012) Xianyun Qin et al.   GENE

Associations among genotype, clinical phenotype, and intracellular localization of trafficking proteins in ARC syndrome

(2012) Holly Smith et al.   HUMAN MUTATION

Prevalence and spectrum of GATA6 mutations associated with familial atrial fibrillation

(2012) Yi-Qing Yang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Mutational spectrum of the GATA5 gene associated with familial atrial fibrillation

(2012) Yi-Qing Yang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Prevalence and spectrum of GATA5 mutations associated with congenital heart disease

(2012) Jin-Qi Jiang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Dilated cardiomyopathy in patients with mutations in anoctamin 5

(2012) K. Wahbi et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Sudden cardiac death in non-ischemic dilated cardiomyopathy: A critical appraisal of existing and potential risk stratification tools

(2012) Emmanuel Koutalas et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Novel GATA6 loss-of-function mutation responsible for familial atrial fibrillation

(2012) JIAN LI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

A novel GATA5 loss-of-function mutation underlies lone atrial fibrillation

(2012) XIN-HUA WANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

R25C mutation in the NKX2.5 gene in Italian patients affected with non-syndromic and syndromic congenital heart disease

(2012) Giorgia Beffagna et al.   Journal of Cardiovascular Medicine

Mutation spectrum of the GATA4 gene in patients with idiopathic atrial fibrillation

(2012) Jun Wang et al.   MOLECULAR BIOLOGY REPORTS

GATA5 Loss-of-Function Mutation Responsible for the Congenital Ventriculoseptal Defect

(2012) Dong Wei et al.   PEDIATRIC CARDIOLOGY

Ablation of the Cardiac-Specific Gene Leucine-Rich Repeat Containing 10 (Lrrc10) Results in Dilated Cardiomyopathy

(2012) Matthew J. Brody et al.   PLoS One

Contribution of Acquired Factors to the Pathogenesis of Dilated Cardiomyopathy

(2011) Tsutomu Yoshikawa   CIRCULATION JOURNAL

The genetics of dilated cardiomyopathy

(2011) English Flack et al.   HEART RHYTHM

Genetic variation in the alternative splicing regulator RBM20 is associated with dilated cardiomyopathy

(2011) Marwan M. Refaat et al.   HEART RHYTHM

A Novel GATA4 Loss-of-Function Mutation Associated With Congenital Ventricular Septal Defect

(2011) Yi-Qing Yang et al.   PEDIATRIC CARDIOLOGY

The Cardiac Transcription Network Modulated by Gata4, Mef2a, Nkx2.5, Srf, Histone Modifications, and MicroRNAs

(2011) Jenny Schlesinger et al.   PLoS Genetics

Prevalence of Desmosomal Protein Gene Mutations in Patients With Dilated Cardiomyopathy

(2010) Perry Elliott et al.   Circulation-Cardiovascular Genetics

Mutational spectrum in the cardiac transcription factor gene NKX2.5 (CSX) associated with congenital heart disease

(2010) B Stallmeyer et al.   CLINICAL GENETICS

NKX2-5: an update on this hypermutable homeodomain protein and its role in human congenital heart disease (CHD)

(2010) Stella Marie Reamon-Buettner et al.   HUMAN MUTATION

Primary contribution to zebrafish heart regeneration by gata4 + cardiomyocytes

(2010) Kazu Kikuchi et al.   NATURE

Slow progressive conduction and contraction defects in loss of Nkx2-5 mice after cardiomyocyte terminal differentiation

(2009) Morihiko Takeda et al.   LABORATORY INVESTIGATION

Perinatal Loss of Nkx2-5 Results in Rapid Conduction and Contraction Defects

(2008) Laura E. Briggs et al.   CIRCULATION RESEARCH