Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes

Pharmacodynamic, pharmacokinetic and tolerability evaluation of concomitant administration of lesinurad and febuxostat in gout patients with hyperuricaemia

(2014) Roy Fleischmann et al.   RHEUMATOLOGY

Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity

(2013) Eleanor Wheeler et al.   NATURE GENETICS

Cornichon Proteins Determine the Subunit Composition of Synaptic AMPA Receptors

(2013) Bruce E. Herring et al.   NEURON

Common dysfunctional variants in ABCG2 are a major cause of early-onset gout

(2013) Hirotaka Matsuo et al.   Scientific Reports

Associations of apolipoprotein A5 (APOA5), glucokinase (GCK) and glucokinase regulatory protein (GCKR) polymorphisms and lifestyle factors with the risk of dyslipidemia and dysglycemia in Japanese ^|^mdash; a cross-sectional data from the J-MICC Study

(2012) Asahi Hishida et al.   ENDOCRINE JOURNAL

1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data

(2012) Jie Huang et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations

(2012) Yukinori Okada et al.   NATURE GENETICS

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

(2012) Anna Köttgen et al.   NATURE GENETICS

Extra-Renal Elimination of Uric Acid via Intestinal Efflux Transporter BCRP/ABCG2

(2012) Atsushi Hosomi et al.   PLoS One

Fate-Restricted Neural Progenitors in the Mammalian Cerebral Cortex

(2012) S. J. Franco et al.   SCIENCE

Decreased extra-renal urate excretion is a common cause of hyperuricemia

(2012) Kimiyoshi Ichida et al.   Nature Communications

Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele

(2011) Adrienne Tin et al.   HUMAN MOLECULAR GENETICS

Identification of low-frequency variants associated with gout and serum uric acid levels

(2011) Patrick Sulem et al.   NATURE GENETICS

Large-scale genome-wide association studies in east Asians identify new genetic loci influencing metabolic traits

(2011) Young Jin Kim et al.   NATURE GENETICS

Pathogenic GLUT9 Mutations Causing Renal Hypouricemia Type 2 (RHUC2)

(2011) Y. Kawamura et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Multiple Genetic Loci Influence Serum Urate Levels and Their Relationship With Gout and Cardiovascular Disease Risk Factors

(2010) Qiong Yang et al.   Circulation-Cardiovascular Genetics

Genome-wide association study of hematological and biochemical traits in a Japanese population

(2010) Yoichiro Kamatani et al.   NATURE GENETICS

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility

(2010) Tanja Zeller et al.   PLoS One

Differential Effects of Chromosome 9p21 Variation on Subphenotypes of Intracranial Aneurysm

(2010) Hirofumi Nakaoka et al.   STROKE

Sodium-dependent phosphate cotransporter type 1 sequence polymorphisms in male patients with gout

(2009) W. Urano et al.   ANNALS OF THE RHEUMATIC DISEASES

Glucokinase regulatory protein gene polymorphism affects postprandial lipemic response in a dietary intervention study

(2009) Haiqing Shen et al.   HUMAN GENETICS

Meta-analysis of genetic association studies: methodologies, between-study heterogeneity and winner's curse

(2009) Hirofumi Nakaoka et al.   JOURNAL OF HUMAN GENETICS

Homozygous SLC2A9 Mutations Cause Severe Renal Hypouricemia

(2009) D. Dinour et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout

(2009) O. M. Woodward et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Proteomics Identify Cornichon Proteins as Auxiliary Subunits of AMPA Receptors

(2009) J. Schwenk et al.   SCIENCE

Common Defects of ABCG2, a High-Capacity Urate Exporter, Cause Gout: A Function-Based Genetic Analysis in a Japanese Population

(2009) H. Matsuo et al.   Science Translational Medicine

Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations

(2009) Melanie Kolz et al.   PLoS Genetics

Mutations in Glucose Transporter 9 Gene SLC2A9 Cause Renal Hypouricemia

(2008) Hirotaka Matsuo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Association of a common nonsynonymous variant in GLUT9 with serum uric acid levels in old order amish

(2008) Patrick F. McArdle et al.   ARTHRITIS AND RHEUMATISM

Cux2 (Cutl2) integrates neural progenitor development with cell-cycle progression during spinal cord neurogenesis

(2008) A. Iulianella et al.   DEVELOPMENT

The Common P446L Polymorphism in GCKR Inversely Modulates Fasting Glucose and Triglyceride Levels and Reduces Type 2 Diabetes Risk in the DESIR Prospective General French Population

(2008) M. Vaxillaire et al.   DIABETES

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

(2008) Abbas Dehghan et al.   LANCET

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

(2008) Veronique Vitart et al.   NATURE GENETICS

SLC2A9 influences uric acid concentrations with pronounced sex-specific effects

(2008) Angela Döring et al.   NATURE GENETICS

The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane

(2007) M. Huls et al.   KIDNEY INTERNATIONAL