Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Multiple Genetic Loci Influence Serum Urate Levels and Their Relationship With Gout and Cardiovascular Disease Risk Factors

(2010) Qiong Yang et al.   Circulation-Cardiovascular Genetics

Candidate Gene Association Resource (CARe)

(2010) Kiran Musunuru et al.   Circulation-Cardiovascular Genetics

Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans

(2010) Ken Sin Lo et al.   HUMAN GENETICS

Increased power of mixed models facilitates association mapping of 10 loci for metabolic traits in an isolated population

(2010) E. E. Kenny et al.   HUMAN MOLECULAR GENETICS

Higher Healthy Eating Index-2005 Scores Associated with Reduced Symptoms of Depression in an Urban Population: Findings from the Healthy Aging in Neighborhoods of Diversity Across the Life Span (HANDLS) Study

(2010) Marie Fanelli Kuczmarski et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Genome-wide association study of hematological and biochemical traits in a Japanese population

(2010) Yoichiro Kamatani et al.   NATURE GENETICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

GWAF: an R package for genome-wide association analyses with family data

(2009) Ming-Huei Chen et al.   BIOINFORMATICS

Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

(2009) Bruce M. Psaty et al.   Circulation-Cardiovascular Genetics

The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver

(2009) Nicola L. Beer et al.   HUMAN MOLECULAR GENETICS

Recent insights into the pathogenesis of hyperuricaemia and gout

(2009) P. L. Riches et al.   HUMAN MOLECULAR GENETICS

Mechanisms of uric acid crystal-mediated autoinflammation

(2009) Fabio Martinon   IMMUNOLOGICAL REVIEWS

Gout

(2009) Pascal Richette et al.   LANCET

Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout

(2009) O. M. Woodward et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common Defects of ABCG2, a High-Capacity Urate Exporter, Cause Gout: A Function-Based Genetic Analysis in a Japanese Population

(2009) H. Matsuo et al.   Science Translational Medicine

Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations

(2009) Melanie Kolz et al.   PLoS Genetics

A Genome-Wide Association Study of Hypertension and Blood Pressure in African Americans

(2009) Adebowale Adeyemo et al.   PLoS Genetics

Genome-wide Association Study Identifies Genes for Biomarkers of Cardiovascular Disease: Serum Urate and Dyslipidemia

(2008) Chris Wallace et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A comprehensive evaluation of SNP genotype imputation

(2008) Michael Nothnagel et al.   HUMAN GENETICS

Plasma Urate Level Is Directly Regulated by a Voltage-driven Urate Efflux Transporter URATv1 (SLC2A9) in Humans

(2008) Naohiko Anzai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

(2008) Abbas Dehghan et al.   LANCET

SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout

(2008) Veronique Vitart et al.   NATURE GENETICS

SLC2A9 influences uric acid concentrations with pronounced sex-specific effects

(2008) Angela Döring et al.   NATURE GENETICS

Uric Acid and Cardiovascular Risk

(2008) Daniel I. Feig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association Studies

(2008) Brendan J. Keating et al.   PLoS One

SLC2A9 Is a High-Capacity Urate Transporter in Humans

(2008) Mark J Caulfield et al.   PLOS MEDICINE