No Donor KMUP-1 Improves Hepatic Ischemia-Reperfusion and Hypoxic Cell Injury by Inhibiting Oxidative Stress and Pro-Inflammatory Signaling

Kmup-1 Inhibits H441 Lung Epithelial Cell Growth, Migration and Proinflammation VIA Increased NO/CGMP and Inhibited RHO KINASE/VEGF Signaling Pathways

(2017) B.N. Wu et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Potassium-Channel Openers KMUP-1 and Pinacidil Prevent Subarachnoid Hemorrhage–Induced Vasospasm by Restoring the BKCa-Channel Activity

(2012) Jun-Yih Chen et al.   SHOCK

Rosiglitazone regulates IL-6-stimulated lipolysis in porcine adipocytes

(2010) Yongqing Yang et al.   Biochemistry and Cell Biology

The xanthine derivative KMUP-1 inhibits models of pulmonary artery hypertension via increased NO and cGMP-dependent inhibition of RhoA/Rho kinase

(2010) Hui-Hsuan Chung et al.   BRITISH JOURNAL OF PHARMACOLOGY

RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis

(2010) Brad A. Bryan et al.   FASEB JOURNAL

Soluble Guanylate Cyclase α1β1 Limits Stroke Size and Attenuates Neurological Injury

(2010) Dmitriy N. Atochin et al.   STROKE

KMUP-1 inhibits pulmonary artery proliferation by targeting serotonin receptors/transporter and NO synthase, inactivating RhoA and suppressing AKT/ERK phosphorylation

(2010) Hui-Hsuan Chung et al.   VASCULAR PHARMACOLOGY

Oxidant stress-induced liver injury in vivo: role of apoptosis, oncotic necrosis, and c-Jun NH2-terminal kinase activation

(2009) Ji-Young Hong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Mitochondrial Glutathione, a Key Survival Antioxidant

(2009) Montserrat Marí et al.   ANTIOXIDANTS & REDOX SIGNALING

Peroxisome Proliferator-Activated Receptor-γ Agonists Promote Differentiation and Antioxidant Defenses of Oligodendrocyte Progenitor Cells

(2009) Antonietta Bernardo et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

KMUP-1 attenuates serum deprivation-induced neurotoxicity in SH-SY5Y cells: Roles of PKG, PI3K/Akt and Bcl-2/Bax pathways

(2009) Ya-Yun Hsu et al.   TOXICOLOGY

Cardioprotective Mechanism of Telmisartan via PPAR- -eNOS Pathway in Dahl Salt-Sensitive Hypertensive Rats

(2008) N. Kobayashi et al.   AMERICAN JOURNAL OF HYPERTENSION

Hepatocellular protection by nitric oxide or nitrite in ischemia and reperfusion injury

(2008) Yuta Abe et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Protein Kinase G-dependent Cardioprotective Mechanism of Phosphodiesterase-5 Inhibition Involves Phosphorylation of ERK and GSK3β

(2008) Anindita Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY