Aging of the hematopoietic stem cells niche

Asymmetry in skeletal distribution of mouse hematopoietic stem cell clones and their equilibration by mobilizing cytokines

(2014) Evgenia Verovskaya et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The relevance of a geriatric assessment for elderly patients with a haematological malignancy – A systematic review

(2014) M.E. Hamaker et al.   LEUKEMIA RESEARCH

Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts

(2014) Aruna Kode et al.   NATURE

Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation

(2014) Yoshiki Omatsu et al.   NATURE

Heterochronic parabiosis: historical perspective and methodological considerations for studies of aging and longevity

(2013) Michael J. Conboy et al.   AGING CELL

Factors impacting stem cell mobilization failure rate and efficiency in multiple myeloma in the era of novel therapies: experience at Memorial Sloan Kettering Cancer Center

(2013) M Pozotrigo et al.   BONE MARROW TRANSPLANTATION

Myeloproliferative Neoplasia Remodels the Endosteal Bone Marrow Niche into a Self-Reinforcing Leukemic Niche

(2013) Koen Schepers et al.   Cell Stem Cell

Heterogeneity in hematopoietic stem cell populations

(2013) Paul H. Miller et al.   CURRENT OPINION IN HEMATOLOGY

Vascular-derived TGF-β increases in the stem cell niche and perturbs neurogenesis during aging and following irradiation in the adult mouse brain

(2013) Jose R. Pineda et al.   EMBO Molecular Medicine

CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance

(2013) Adam Greenbaum et al.   NATURE

Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches

(2013) Lei Ding et al.   NATURE

Extracellular matrix protein tenascin-C is required in the bone marrow microenvironment primed for hematopoietic regeneration

(2012) A. Nakamura-Ishizu et al.   BLOOD

Rejuvenation of Regeneration in the Aging Central Nervous System

(2012) Julia M. Ruckh et al.   Cell Stem Cell

Cdc42 Activity Regulates Hematopoietic Stem Cell Aging and Rejuvenation

(2012) Maria Carolina Florian et al.   Cell Stem Cell

Myelodysplastic syndromes: revisiting the role of the bone marrow microenvironment in disease pathogenesis

(2012) Marc H. G. P. Raaijmakers   INTERNATIONAL JOURNAL OF HEMATOLOGY

The let-7–Imp axis regulates ageing of the Drosophila testis stem-cell niche

(2012) Hila Toledano et al.   NATURE

Endothelial and perivascular cells maintain haematopoietic stem cells

(2012) Lei Ding et al.   NATURE

Contribution of an Aged Microenvironment to Aging-Associated Myeloproliferative Disease

(2012) Virag Vas et al.   PLoS One

Aging of the Microenvironment Influences Clonality in Hematopoiesis

(2012) Virag Vas et al.   PLoS One

Continuous and Uninterrupted Oxygen Tension Influences the Colony Formation and Oxidative Metabolism of Human Mesenchymal Stem Cells

(2012) Girish Pattappa et al.   TISSUE ENGINEERING PART C-METHODS

Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche

(2011) Satoshi Yamazaki et al.   CELL

The stem cell niche: lessons from the Drosophila testis

(2011) M. de Cuevas et al.   DEVELOPMENT

Bone marrow CD169+macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

(2011) Andrew Chow et al.   JOURNAL OF EXPERIMENTAL MEDICINE

In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche

(2011) Joji Fujisaki et al.   NATURE

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

(2011) Saul A. Villeda et al.   NATURE

Control of hematopoietic stem cells by the bone marrow stromal niche: the role of reticular cells

(2011) Takashi Nagasawa et al.   TRENDS IN IMMUNOLOGY

Knockdown of N-cadherin suppresses the long-term engraftment of hematopoietic stem cells

(2010) K. Hosokawa et al.   BLOOD

Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells

(2010) Jason M. Butler et al.   Cell Stem Cell

Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia

(2010) Marc H. G. P. Raaijmakers et al.   NATURE

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

(2010) Simón Méndez-Ferrer et al.   NATURE

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

(2010) I. Beerman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation

(2010) L. Yvan-Charvet et al.   SCIENCE

Relative roles of TGF-β1 and Wnt in the systemic regulation and aging of satellite cell responses

(2009) Morgan E. Carlson et al.   AGING CELL

Aging of marrow stromal (skeletal) stem cells and their contribution to age-related bone loss

(2009) Ilaria Bellantuono et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

DLL1-mediated Notch activation regulates endothelial identity in mouse fetal arteries

(2009) I. Sorensen et al.   BLOOD

Altered cellular dynamics and endosteal location of aged early hematopoietic progenitor cells revealed by time-lapse intravital imaging in long bones

(2009) A. Kohler et al.   BLOOD

The leukemic stem cell niche: current concepts and therapeutic opportunities

(2009) S. W. Lane et al.   BLOOD

Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment

(2009) Olaia Naveiras et al.   NATURE

Fanconi DNA repair pathway is required for survival and long-term maintenance of neural progenitors

(2008) Karine Sii-Felice et al.   EMBO JOURNAL

Aging of hematopoietic stem cells is regulated by the stem cell niche

(2008) Wolfgang Wagner et al.   EXPERIMENTAL GERONTOLOGY

Age-related changes in human bone marrow-derived mesenchymal stem cells: Consequences for cell therapies

(2007) A. Stolzing et al.   MECHANISMS OF AGEING AND DEVELOPMENT