Purple sweet potato colour – a potential therapy for galactosemia?

Misfolding of galactose 1-phosphate uridylyltransferase can result in type I galactosemia

(2013) Thomas J. McCorvie et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

In silico prediction of the effects of mutations in the human UDP-galactose 4′-epimerase gene: Towards a predictive framework for type III galactosemia

(2013) Thomas J. McCorvie et al.   GENE

Altered cofactor binding affects stability and activity of human UDP-galactose 4′-epimerase: Implications for type III galactosemia

(2012) Thomas J. McCorvie et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Oxidative stress contributes to outcome severity in a Drosophila melanogaster model of classic galactosemia

(2012) P. P. Jumbo-Lucioni et al.   Disease Models & Mechanisms

N- and O-linked glycosylation of total plasma glycoproteins in galactosemia

(2012) Ying Liu et al.   MOLECULAR GENETICS AND METABOLISM

Structural and molecular biology of type I galactosemia: Disease-associated mutations

(2011) Thomas J. McCorvie et al.   IUBMB LIFE

Innovative therapy for Classic Galactosemia — Tale of two HTS

(2011) M. Tang et al.   MOLECULAR GENETICS AND METABOLISM

Molecular and biochemical characterization of human galactokinase and its small molecule inhibitors

(2010) M. Tang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

UDP-galactose 4' epimerase (GALE) is essential for development of Drosophila melanogaster

(2010) R. D. Sanders et al.   Disease Models & Mechanisms

A Drosophila melanogaster model of classic galactosemia

(2010) R. F. Kushner et al.   Disease Models & Mechanisms

Purple sweet potato color protects mouse liver against d-galactose-induced apoptosis via inhibiting caspase-3 activation and enhancing PI3K/Akt pathway

(2010) Zi-feng Zhang et al.   FOOD AND CHEMICAL TOXICOLOGY

Purple Sweet Potato Color Alleviates D-galactose-induced Brain Aging in Old Mice by Promoting Survival of Neurons via PI3K Pathway and Inhibiting Cytochrome C-mediated Apoptosis

(2009) Jun Lu et al.   BRAIN PATHOLOGY

Functional analysis of mutations in UDP-galactose-4-epimerase (GALE) associated with galactosemia in Korean patients using mammalian GALE-null cells

(2009) You-Lim Bang et al.   FEBS Journal

Purple Sweet Potato Color Ameliorates Cognition Deficits and Attenuates Oxidative Damage and Inflammation in Aging Mouse Brain Induced by D-Galactose

(2009) Qun Shan et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Purple sweet potato color attenuates oxidative stress and inflammatory response induced by d-galactose in mouse liver

(2008) Zi-Feng Zhang et al.   FOOD AND CHEMICAL TOXICOLOGY

Purple sweet potato color repairs d-galactose-induced spatial learning and memory impairment by regulating the expression of synaptic proteins

(2008) Dong-mei Wu et al.   NEUROBIOLOGY OF LEARNING AND MEMORY