Article
Biochemistry & Molecular Biology
Claudia Volpi, Desiree Bartolini, Virginia Brighenti, Francesco Galli, Matteo Tiecco, Federica Pellati, Catia Clementi, Roccaldo Sardella
Summary: This study enhanced the phenol loading and antioxidant activity of wool yarn with onion skin extract by using alum as a mordant. The pre-mordanted sample showed elevated dye uptake on wool and released main phenolic acids that significantly reduced ROS levels in cells. These findings suggest that alum pre-mordanted textiles dyed with onion-skin extracts could be a promising tool against skin diseases.
Article
Horticulture
Nadezhda Golubkina, Carmine Amalfitano, Agnieszka Sekara, Alessio Tallarita, Robert Pokluda, Vasile Stoleru, Antonio Cuciniello, Alexander F. Agafonov, Andrzej Kalisz, Silvia Brindusa Hamburda, Gianluca Caruso
Summary: The need for sustainable management systems is driven by environmental protection and consumer demand for safe, high-quality food. A research study compared the effects of organic and conventional farming systems, nitrogen doses, and cultivars on onion bulb yield, quality, antioxidants, elemental composition, and heavy metal content. The results showed that conventional farming generally led to higher bulb yield and nutrient content, while organic farming had a positive impact on overall bulb quality. The optimal nitrogen dose for balancing yield and quality was found to be 166.5 kg/ha.
SCIENTIA HORTICULTURAE
(2022)
Article
Food Science & Technology
Carolina Medina-Jaramillo, Edward Gomez-Delgado, Alex Lopez-Cordoba
Summary: The optimal ultrasound-assisted extraction conditions for obtaining extracts with high polyphenols content and DPPH scavenging activity from Welsh onion leaves were determined. The extracts showed strong antioxidant activity and contained abundant cyanidin and quercetin-3-glucoside compounds.
Article
Food Science & Technology
Pei Pu, Zhifen Deng, Lang Chen, Han Yang, Guizhao Liang
Summary: This study investigates the effect of covalent modification by six natural compounds on the antigenicity and antioxidant characteristics of beta-LG, revealing that the covalent interaction with flavonoids reduces the antigenicity of beta-LG and enhances its antioxidant capacity.
Article
Biochemistry & Molecular Biology
Nikola Major, Nina Isic, Tvrtko Karlo Kovacevic, Magdalena Andelini, Dean Ban, Melissa Prelac, Igor Palcic, Smiljana Goreta Ban
Summary: This study investigates the biochemical and nutritional aspects of the sweet onion landrace Premanturska kapula, as well as the influence of onion bulb size on onion phytochemical and nutritional profile. It is found that Premanturska kapula has a high content of soluble sugar, antioxidant capacity, and phenolic compounds. The choice of onion bulb size affects the profile of sugars present, with large bulbs favoring higher sucrose and fructooligosaccharides content, while small bulbs are more abundant in glucose.
Article
Chemistry, Applied
Lubna Mobin, Mohammad Abdul Haq, Rashida Ali, Shahina Naz, Syed Ghufran Saeed
Summary: The aqueous methanolic extract of the outer peel of onions was fractionated into anthocyanin, acidic phenols, flavanols, and flavonols, with the HLB fractions showing higher total phenols and bio functional activity. All fractions exhibited antimicrobial activity, with phenolic acids being the most active and flavanols the least. Flavonols showed the highest antioxidant potential and LOX inhibition. HPLC analysis revealed the presence of specific compounds in different phenolic fractions.
NATURAL PRODUCT RESEARCH
(2022)
Article
Food Science & Technology
Blanca Moreno Gracia, Diego Laya Reig, Maria Jose Rubio-Cabetas, Maria Angeles Sanz Garcia
Summary: Phenolic compounds in almonds have beneficial health properties, and optimizing extraction methods can determine the total amount of polyphenols, flavonoids, and proanthocyanidins. Different almond genotypes show variation in antioxidant content, which can affect fruit quality.
Article
Food Science & Technology
Temitope Omolayo Fasuan, Chidubem Theresa Chukwu, Nneka Nkechi Uchegbu, Titilope Modupe Olagunju, Kenneth Chigozie Asadu, Mabel Chidinma Nwachukwu
Summary: Organic white cultivar of Vigna unguiculata grains exhibited superior bioactive compounds, phytochemicals, and thermal properties compared to nonorganic grains. The organic grains are rich in health-promoting compounds and have the potential to be used as an active ingredient in the development of functional foods.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2022)
Article
Food Science & Technology
Zein Najjar, Jaleel Kizhakkayil, Hira Shakoor, Carine Platat, Constantinos Stathopoulos, Meththa Ranasinghe
Summary: This study explores the use of date seeds, a byproduct of the food industry, as a means to improve the nutritional value and antioxidant activity of cookies. The results show that the seeds contain high levels of polyphenols and flavonoids, and substituting flour with ground date seed enhances the cookies' antioxidant properties.
Article
Biochemistry & Molecular Biology
Alice Cattivelli, Lorenzo Nissen, Flavia Casciano, Davide Tagliazucchi, Andrea Gianotti
Summary: In this study, the stability and bioaccessibility of phenolics in differently cooked red-skinned onion were investigated. The results showed that raw onions had a significant increase in beneficial taxa and higher inhibition of opportunistic bacteria compared to heat-treated onions. This study is one of the first to explore the impact of different cooking methods on phenolic metabolism and microbiota composition in the large intestine of humans, providing important insights for fine-tuning the antioxidant nature of foods.
Article
Biochemistry & Molecular Biology
Cristina Moliner, Sonia Nunez, Guillermo Casedas, Marta Sofia Valero, Maria Ines Dias, Lillian Barros, Victor Lopez, Carlota Gomez-Rincon
Summary: This study aimed to determine the polyphenolic profile of onion flowers and evaluate their antioxidant and anti-obesity capacity. The phenolic compounds kaempferol and isorhamnetin glucosides were identified, and the flower extract exhibited the ability to reduce fat accumulation, inhibit digestive enzyme activity, and enhance antioxidant activity. This suggests that onion flowers have potential as functional foods and nutraceuticals.
Article
Food Science & Technology
Wellington Mamoro Umeda, Neuza Jorge
Summary: The study found that the combination of purple onion peel extract with synthetic antioxidants can delay the oxidation reaction during the storage of soybean oil, potentially reducing the concentration of synthetic antioxidants used.
Article
Oncology
Matin Ghanavati, Cain C. T. Clark, Alireza Bahrami, Farshad Teymoori, Mehdi Movahed, Golbon Sohrab, Ehsan Hejazi
Summary: The study found that the consumption of certain polyphenols can significantly reduce the risk of prostate cancer.
EUROPEAN JOURNAL OF CANCER CARE
(2021)
Article
Chemistry, Applied
Leilei Zhang, Pascual Garcia-Perez, Busra Arikan, Fevzi Elbasan, Fatma Nur Alp, Melike Balci, Gokhan Zengin, Evren Yildiztugay, Luigi Lucini
Summary: This study found that wood vinegar can be applied to onions to enhance their nutritional and health-promoting properties. Wood vinegar had tissue and dose-specific effects on the onion metabolome, improving antioxidant and enzyme-inhibiting capabilities. Moderate to high concentrations of wood vinegar (250-500 mu L L 1) were found to be optimal for enhancing biological activities.
Article
Food Science & Technology
Silvia Tagliamonte, Raffaele Romano, Manuela Flavia Chiacchio, Alessandra Aiello, Lucia De Luca, Vincenzo Salzano, Paola Vitaglione
Summary: This study aimed to reutilize tomato pomace, a by-product of the tomato-processing industry, in the development of tomato sauce and assess its nutritional content and bioaccessibility. The innovative tomato sauce products showed higher levels of carotenoids, α-tocopherol, and total antioxidant capacity (TAC) compared to traditional sauce. Bioaccessibility of carotenoids and α-tocopherol varied among the different tomato sauce formulations, while total polyphenols content was higher in the sauce with 100% tomato pomace.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Analytical
Asuman Cifteci, Saliha Esin Celik, Resat Apak
Summary: This study developed a method for determining biothiols in sulfhydryl and disulfide forms using a fluorometric sensor composed of citrate-stabilized gold nanoparticles and Rhodamine-6G dye. The method can differentiate between oxidized and reduced thiols, measure thiol/disulfide homeostasis, and is selective over potential interfering compounds. It also allows for naked-eye detection of biothiols and can be applied to pharmaceutical samples containing thiols.
ANALYTICAL LETTERS
(2022)
Review
Chemistry, Analytical
Sema Demirci-Cekic, Gulay Ozkan, Asli Neslihan Avan, Seda Uzunboy, Esra Capanoglu, Resat Apak
Summary: Reactive oxygen and nitrogen species produced during normal metabolism in the human body play important roles in signal transmission and the immune system, but an imbalance between oxidants and antioxidants can lead to oxidative stress and diseases. Maintaining a balanced antioxidant defense system is crucial for overall health and disease prevention.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
Article
Chemistry, Multidisciplinary
Resat Apak, Antony Calokerinos, Shela Gorinstein, Marcela Alves Segundo, David Brynn Hibbert, Ilhami Gulcin, Sema Demirci Cekic, Kubilay Guclu, Mustafa Ozyurek, Saliha Esin Celik, Luis M. Magalhaes, Patricia Arancibia-Avila
Summary: This project aims to investigate the quenching chemistry of biologically important reactive oxygen and nitrogen species, evaluate the scavenging activity of antioxidants with existing methods, and emphasize the need for developing more refined assays to provide a comprehensive study of antioxidants and reactive species.
PURE AND APPLIED CHEMISTRY
(2022)
Editorial Material
Chemistry, Analytical
Mustafa Soylak, Resat Apak
Summary: This special issue of Analytical Letters features selected articles from the Third International Congress of Environmental Chemistry (EnviroChem 2021), in which the authors have expanded upon their conference papers and included their latest experimental results. EnviroChem 2021 aimed to promote and disseminate knowledge on various topics and technologies related to Environmental Chemistry. All articles have undergone the standard review process.
ANALYTICAL LETTERS
(2023)
Review
Chemistry, Analytical
Resat Apak, Aysem Uzer, Sener Saglam, Aysu Arman
Summary: Explosive detection technologies play a critical role in national security, and there is a demand for improved sensitivity and selectivity in current detection techniques. Electrochemical devices combined with nanomaterials offer a simpler, cheaper, and faster way to obtain targeted analytical information. This review focuses on providing information related to MIPs and nanomaterial-based electrochemical sensors.
Editorial Material
Chemistry, Multidisciplinary
Antony C. Calokerinos, Resat Apak, Mustafa Bener
APPLIED SCIENCES-BASEL
(2022)
Article
Chemistry, Analytical
Sener Saglam, Aysem Uzer, Resat Apak
Summary: In this study, a novel electrochemical sensor was developed for the direct and selective determination of peroxide-based explosives. The sensor showed high sensitivity and accuracy, and was able to detect intact explosives in the presence of camouflage materials.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Applied
Natavan Hasanova, Saliha Esin Celik, Resat Apak
Summary: A simple and sensitive nanoparticle-based fluorometric method has been developed to determine the total content of biogenic amines in food samples. This method provides important information about the quality and safety of food products.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2022)
Article
Spectroscopy
Herbert Cirrus Kaboggoza, Burcu Bekdeser, Resat Apak
Summary: A fluorescent gold nanocluster was used to determine the peroxyl radical scavenging activity of antioxidants. The addition of glutathione enhanced the fluorescence intensity of the gold nanoclusters, while antioxidants reduced the decline in fluorescence intensity caused by peroxyl radical attack. This method provides a simple and selective estimation of peroxyl radical scavenging activity in complex matrices.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Multidisciplinary
Ayse Nur Onem, Kevser Sozgen Baskan, Resat Apak
Summary: In this study, a gold nanoparticle (AuNP)-decorated and multiwalled carbon nanotube (MWCNT)-Nafion-modified glassy carbon electrode (GCE/AuNP/MWCNT-Nafion) was developed to assess the preventive effect of antioxidants on oxidative DNA damage. The electrochemical method relied on two phenomena: (i) reactive species (RS) produced by dissolved oxygen in the presence of copper(II) partially damaged the DNA immobilized on the electrode surface, and (ii) antioxidant compounds prevented this damage by scavenging the formed RS. The DNA protective ability of various antioxidant compounds was evaluated, with quercetin showing the highest antioxidant effect.
Article
Chemistry, Multidisciplinary
Batuhan Yardimci, Aysem Uzer, Resat Apak
Summary: In this study, a novel and eco-friendly chromogenic agent for fluoride determination was developed using green analytical chemistry. The method made use of a non-toxic Al(III)-flavonoid complex from St. John's wort plant extract. The method showed a linear response within the F- concentration range of 0.11-1.32 mM, with low LOD and LOQ values that met the permissible limits for fluoride in water. Interference effects from common anions and cations were investigated and easily eliminated with specific techniques. The method was successfully applied to real water samples and validated against a reference spectroscopic method.
Article
Nanoscience & Nanotechnology
Omer Kaan Koc, Aysem Uzer, Resat Apak
Summary: Oxygen- and nitrogen-heteroatom-doped carbon dots were prepared for the selective and sensitive determination of picric acid. The fluorescence of the carbon dots was selectively quenched by picric acid through ground-state interaction. The detection limits for picric acid were 12.5 pM (by emission measurement) and 0.9 nM (by absorption measurement). Smartphone-assisted fluorometric detection of picric acid was also achieved by incorporating the carbon dots into a polymer composite film.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Analytical
Aysu Arman, Sener Saglam, Aysem Uzer, Resat Apak
Summary: This work presents a novel sensor electrode for electrocatalytic reduction of nitro-aromatic explosives (NAEs) by combining electrochemically reduced graphene nanosheets (GNSs) with a poly-caffeic acid (pCAF) film-modified glassy carbon electrode (GCE). The sensor showed high performance for TNT detection and could accurately determine various NAEs. The optimized electrode demonstrated resistance to interference effects and satisfactory results in real samples.
Article
Nanoscience & Nanotechnology
Omer Kaan Koc, Aysem Uzer, Resat Apak
Summary: Oxygen- and nitrogen-heteroatom-doped carbon dots were prepared for the selective and sensitive determination of picric acid, and their fluorescence properties were characterized. The results showed that these carbon dots can selectively detect picric acid in the presence of other explosives.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Abdoul Kader Alassane Moussa, Sener Saglam, Aysem Uzer, Resat Apak
Summary: A novel electrochemical method was developed for the determination of nitroguanidine (NG) using a modified glassy carbon electrode surface. The method showed sensitivity and selectivity, and was successfully applied in various samples with high recoveries.
NEW JOURNAL OF CHEMISTRY
(2022)