Article
Multidisciplinary Sciences
Raveen Rathnasinghe, Sonia Jangra, Lisa Miorin, Michael Schotsasert, Clifford Yahnke, Adolfo Garcia-Sastre
Summary: Research shows that visible light (405 nm) has potential in germicidal applications, utilizing reactive oxygen species to deactivate pathogens, especially effective against respiratory pathogens such as SARS-CoV-2 and influenza virus. This method, which is porphyrin-independent, is safe and commercially viable.
SCIENTIFIC REPORTS
(2021)
Article
Food Science & Technology
Zhanwen Zheng, Yawen Xie, Sheng Ma, Junhong Tu, Jiahui Li, Sen Liang, Yunfeng Xu, Chao Shi
Summary: The study demonstrated that 405-nm LED light effectively inactivated C. sakazakii in PIF, reducing its tolerance to various environmental stressors. LED illumination also downregulated the transcription levels of tolerance-associated genes and caused damage to bacterial cell membranes. This suggests the potential of 405-nm LED technology in preventing and controlling pathogens in food processing and storage environments.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Microbiology
Viswanath Ragupathy, Mohan Haleyurgirisetty, Neetu Dahiya, Caitlin Stewart, John Anderson, Scott MacGregor, Michelle Maclean, Indira Hewlett, Chintamani Atreya
Summary: Despite advances in ensuring blood supply safety, there is still a risk of transfusion transmitted infections (TTIs) from emerging infections. New pathogen reduction technologies (PRTs) using violet-blue light at 405 nm have shown promise in effectively inactivating pathogens in blood, including bacteria, parasites, and viruses.
Article
Biotechnology & Applied Microbiology
Hanyu Chen, Carmen Moraru
Summary: This study explores the potential of using sequential treatments with different wavelengths to enhance the disinfection performance of individual treatments against foodborne pathogens. The results show that pre-treatments with 280 and 222 nm can increase the effectiveness of follow-up 405 nm treatments by inducing higher levels of cellular membrane damage and oxidative stress. These findings provide useful information for light equipment manufacturers, food processors, and healthcare users, and have the potential to improve germicidal light technologies and enhance food safety and public health.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2023)
Article
Materials Science, Multidisciplinary
Louise Breloy, Vlasta Brezova, Zuzana Barbierikova, Yoshihiro Ito, Jun Akimoto, Annalisa Chiappone, Samir Abbad-Andaloussi, Jean-Pierre Malval, Davy-Louis Versace
Summary: This study reported the high initiating properties of quinizarin derivatives under visible-light irradiation, achieving high conversions when combined with various co-initiators. The use of soybean oil acrylate led to highly cross-linked materials with comparable mechanical properties under visible-light. Moreover, the copolymerization of the photosensitizer with the polymer matrix not only prevented leakage, but also ensured antiadhesion properties against Staphylococcus aureus under visible-light activation.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Optics
Zhong Wang, Muling Chen, Weihua Zhang
Summary: We investigated the super-resolution light modulation capability of Si nanodisks in the visible spectral range. By developing an optimization algorithm based on Laguerre-Gaussian beams, focused spots below 45 nm were achieved with 405 nm light. The ability to synthesize complex nano-patterns by superposing multiple focus spots together suggests that Si nanodisks hold promise as a tool for super-resolution photolithography.
Article
Food Science & Technology
Du Guo, Yichen Bai, Shengyi Fei, Yanpeng Yang, Jiahui Li, Baowei Yang, Xin Lu, Xiaodong Xia, Chao Shi
Summary: The research findings suggest that 405 nm LED-illumination treatment reduces the resistance of S. Typhimurium to environmental stress and downregulates the transcription levels of environmental tolerance-related genes. These results provide potential application prospects for using LED-illumination technology to control pathogens in food processing and reduce infections and diseases related to S. Typhimurium.
Article
Biochemistry & Molecular Biology
Akihiro Shirai, Kaito Kawasaka, Koichiro Tsuchiya
Summary: The aim of this study was to investigate the fungicidal spectrum of six phenolic-cinnamic and-benzoic acid derivatives using four fungi, and to assess the mechanism of action involving oxidative damage. The results showed that ferulic acid and vanillic acid exhibited synergistic activity with 405-nm light irradiation, leading to decreased viability of the fungi. The study also revealed the generation of reactive oxygen species and a decrease in intracellular ATP levels, which resulted in growth delay.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2022)
Article
Engineering, Environmental
Alejandro Bembibre, Majdi Benamara, Mokhtar Hjiri, Elvira Gomez, Hatem R. Alamri, Ramzi Dhahri, Albert Serra
Summary: The study explores the efficient mineralization of tetracycline antibiotics using Ca-doped ZnO nanopowders under LED visible light and ultrasound irradiation. The catalyst exhibited high efficiency, reusability, and minimal sonophotocorrosion, especially in natural waters' pH range.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Biochemistry & Molecular Biology
Shijie Huang, Haokuan Qin, Muqing Liu
Summary: The study compared the photoinactivation effect of continuous wave (CW) and pulsed blue light, and found that pulsed 405 nm light had a better antimicrobial effect on E. coli, causing increasing damage of cell membrane, possibly due to ROS production in bacteria.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2023)
Article
Multidisciplinary Sciences
Luluil Maknuna, Van Nam Tran, Byeong-Il Lee, Hyun Wook Kang
Summary: The clinical use of urethral stents is often complicated by adverse effects such as dysuria, fever, and urinary tract infections (UTIs). Researchers aimed to evaluate the efficacy of a new optical treatment using a 405 nm laser to inhibit bacterial growth in urethral stents. By irradiating the stent with 405 nm light for 10 minutes, the biofilm formation was significantly reduced without toxicity.
SCIENTIFIC REPORTS
(2023)
Article
Medical Informatics
Lucy G. Sinclair, Laura R. Dougall, Zornitsa Ilieva, Karen McKenzie, John G. Anderson, Scott J. MacGregor, Michelle Maclean
Summary: This study characterizes the optical output and antibacterial efficacy of a low irradiance 405nm light system for environmental decontamination. The results show that this system has significant inactivation effect on bacteria under laboratory conditions. It has the potential for practical application in infection control.
HEALTH AND TECHNOLOGY
(2023)
Article
Engineering, Electrical & Electronic
Rifat Ksack, Muhammed Yaser Yagan, Murat Uysal, Ali Emre Pusane, Tuncer Baykas, Gunhan Dundar, Arda Deniz Yalcinkaya
Summary: Visible light communication (VLC) is an emerging technology that faces limitations in data transmission due to the modulation bandwidth of LEDs. This paper presents a power-efficient VLC receiver with a switchable equalizer that supports LEDs with different bandwidths. Experimental results show significant improvement in data rate for different tested LEDs.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2022)
Article
Food Science & Technology
Bruna Barnei Saraiva, Katiele da Silva Souza Campanholi, Rayanne Regina Beltrame Machado, Celso Vataru Nakamura, Alessandra Aparecida Silva, Wilker Caetano, Magali Soares dos Santos Pozza
Summary: This study determined the phototoxic potential of riboflavin and curcumin against P.florescens and found that photodynamic inactivation is an alternative method to reduce contaminating microorganisms in food.
INTERNATIONAL DAIRY JOURNAL
(2024)
Article
Nanoscience & Nanotechnology
Jingze Li, Jiaxin Ma, Liu Hong, Cheng Yang
Summary: This study successfully decorated copper nanoparticles on molybdenum disulfide nanosheets, forming CuNPs/MoS2 composite with superior antibacterial performances. The synthesized composite demonstrated almost 100% bacterial kill towards both Gram-negative E. coli and Gram-positive S. aureus, and the bactericidal effect could last for at least 6 hours. The antibacterial properties of CuNPs/MoS2 were attributed to the synergism of photodynamic generated hydroxyl radical, oxidative stress without reactive oxygen species production and the release of Cu ions.
Article
Physics, Fluids & Plasmas
Chris Williamson, Igor V. Timoshkin, Scott J. MacGregor, Mark P. Wilson, Martin J. Given, Mark Sinclair, Aled Jones
Summary: This study reports the results of impulse breakdown tests on different insulating liquids under highly divergent electric field conditions, revealing a strong dependence of breakdown voltage and time on the polarity of the applied HV impulses.
IEEE TRANSACTIONS ON PLASMA SCIENCE
(2021)
Article
Physics, Fluids & Plasmas
Zhe Wang, Igor V. Timoshkin, Mark P. Wilson, Martin J. Given, Tao Wang, Scott J. MacGregor
Summary: Comprehensive knowledge and understanding of the breakdown behavior of solid-gas interfaces is crucial for the development and optimization of insulation in high-voltage gas-insulated systems. This study experimentally investigates the breakdown behavior of solid-gas interfaces formed between solid dielectrics and common gases, providing useful insights for the development and optimization of dielectric topologies in GISs.
IEEE TRANSACTIONS ON PLASMA SCIENCE
(2021)
Article
Medicine, General & Internal
Katarzyna Jankowska, Rana Nagarkatti, Nirmallya Acharyya, Neetu Dahiya, Caitlin F. Stewart, Ruairidh W. Macpherson, Mark P. Wilson, John G. Anderson, Scott J. MacGregor, Michelle Maclean, Neil Dey, Alain Debrabant, Chintamani D. Atreya
FRONTIERS IN MEDICINE
(2020)
Article
Physics, Fluids & Plasmas
Yuan Yao, Igor V. Timoshkin, Scott J. MacGregor, Mark P. Wilson, Martin J. Given, Tao Wang
Summary: Gas-filled plasma closing switches (PCSs) are crucial components of high energy density pulsed power systems, generating short, high-power impulses. Research on the dynamic plasma resistance of PCSs shows its significant impact on the rise time and power delivery of the generated impulses.
IEEE TRANSACTIONS ON PLASMA SCIENCE
(2021)
Article
Engineering, Electrical & Electronic
Qingjiang Xue, Igor Timoshkin, Mark P. Wilson, Martin Given, Scott J. MacGregor
Summary: This study investigated the charge carrier mobility in natural and synthetic ester fluids as well as mineral oil, finding that the mobility is higher in mineral oil than in ester fluids. The mobility increases with higher applied electric field, which is significant for characterizing liquid dielectrics and optimizing high-voltage systems.
Article
Biochemistry & Molecular Biology
Caitlin F. Stewart, Rachael M. Tomb, Heather J. Ralston, Jack Armstrong, John G. Anderson, Scott J. MacGregor, Chintamani D. Atreya, Michelle Maclean
Summary: This study demonstrates that the use of 405-nm light can effectively and safely inactivate bacteria in ex vivo stored blood plasma, while preserving protein integrity. These findings highlight the potential of 405-nm light for improving blood safety and reducing transfusion-transmitted infections.
PHOTOCHEMISTRY AND PHOTOBIOLOGY
(2022)
Article
Microbiology
Viswanath Ragupathy, Mohan Haleyurgirisetty, Neetu Dahiya, Caitlin Stewart, John Anderson, Scott MacGregor, Michelle Maclean, Indira Hewlett, Chintamani Atreya
Summary: Despite advances in ensuring blood supply safety, there is still a risk of transfusion transmitted infections (TTIs) from emerging infections. New pathogen reduction technologies (PRTs) using violet-blue light at 405 nm have shown promise in effectively inactivating pathogens in blood, including bacteria, parasites, and viruses.
Article
Engineering, Electrical & Electronic
Timothy Wong, Igor Timoshkin, Scott MacGregor, Mark Wilson, Martin Given
Summary: This article presents a theoretical analysis of composite electrical insulation made up of layered dielectric materials and subjected to impulsive energization. Analytical solutions have been derived for the time-dependent electric field inside each layer. The model is useful for designing and coordinating functionally graded materials and composite insulation for high-voltage systems under fast-rising impulsive conditions.
IEEE TRANSACTIONS ON DIELECTRICS AND ELECTRICAL INSULATION
(2023)
Article
Physics, Fluids & Plasmas
Xu Guo, Ying Sun, Chen-Lei Liu, Lin Jing, Yuan-Tao Zhang, Xiao-Long Wang, Igor Timoshkin
Summary: This paper investigates the guiding effect of injected bubbles on the pre-breakdown process of underwater pulsed spark discharges and explores potential correlations between their subsequent electrical and acoustic parameters to optimize acoustic emission. Experimental and numerical observations are conducted on the dynamics of injected bubbles and different guiding modes of plasma streamers' propagation. The electrical properties of gas-bubble-guided spark discharges are analyzed in relation to breakdown voltage, enabling the verification of dependencies between acoustic wave amplitude and efficiency with these electrical parameters, providing regulation principles for optimizing the plasma-acoustic system.
PHYSICS OF PLASMAS
(2022)
Article
Biochemistry & Molecular Biology
Lucy G. Sinclair, Zornitsa Ilieva, Georgina Morris, John G. Anderson, Scott J. MacGregor, Michelle Maclean
Summary: This study investigates the efficacy of a low irradiance 405-nm light environmental decontamination system for the inactivation of bacteriophage phi6 as a surrogate for SARS-CoV-2. Complete/near-complete inactivation was demonstrated in all cases, with significantly enhanced reductions observed in biologically relevant media. The findings establish the efficacy of low irradiance 405-nm light systems for inactivation of a SARS-CoV-2 surrogate and demonstrate the significant enhancement in susceptibility when suspended in saliva, which is a major vector in COVID-19 transmission.
PHOTOCHEMISTRY AND PHOTOBIOLOGY
(2023)
Article
Medical Informatics
Lucy G. Sinclair, Laura R. Dougall, Zornitsa Ilieva, Karen McKenzie, John G. Anderson, Scott J. MacGregor, Michelle Maclean
Summary: This study characterizes the optical output and antibacterial efficacy of a low irradiance 405nm light system for environmental decontamination. The results show that this system has significant inactivation effect on bacteria under laboratory conditions. It has the potential for practical application in infection control.
HEALTH AND TECHNOLOGY
(2023)
Article
Engineering, Electrical & Electronic
T. Wong, I. Timoshkin, S. MacGregor, M. Wilson, M. Given
Summary: This article gives a comprehensive introduction to dielectric interfaces, discussing various technologies involving them, presenting the basic theoretical treatment of interfacial phenomena, and briefly mentioning interfacial breakdown.
IEEE ELECTRICAL INSULATION MAGAZINE
(2023)
Article
Computer Science, Information Systems
Timothy Wong, Igor Timoshkin, Scott MacGregor, Mark Wilson, Martin Given
Summary: In recent years, there has been a significant increase in interest and development of nonthermal plasma technologies. These technologies have found applications in various fields such as plasma medicine, chemical processing, pollution control, and surface treatment. This article presents the development of the StrAFE package, a Python library designed to simplify and automate the solution of ionization front models. The results obtained from this open-source framework are comparable to other established software, demonstrating the potential of open-source software in the field of nonthermal plasmas.
Article
Physics, Fluids & Plasmas
Ting Liu, Igor Timoshkin, Mark P. Wilson, Martin J. Given, Scott J. MacGregor
Summary: This paper investigates the breakdown characteristics of gases present in the atmosphere (air, N-2, and CO2) during the rising edge of HV impulses. Experimental results were obtained by applying sub-microsecond impulses with rise times up to 50 ns to a 100 μm gap between an HV needle and ground electrode. The scaling relationships between the reduced breakdown field and gas number density and inter-electrode gap were obtained for a wide range of gas densities.
Article
Physics, Fluids & Plasmas
Zhongshu Zhang, Mark P. Wilson, Scott J. MacGregor, Igor Timoshkin, Martin Given, Tao Wang
PLASMA SOURCES SCIENCE & TECHNOLOGY
(2020)
Article
Food Science & Technology
Guangfei Wei, Yichuan Liang, Guozhuang Zhang, Zhaoyu Zhang, Yongqing Zhang, Shilin Chen, Linlin Dong
Summary: This study investigated the presence of fungi on the surface of Polygonum multiflorum Thunb and found that it is easily contaminated by toxigenic fungi and mycotoxins, posing a health risk for consumers. The results also showed that sampling location and processing can influence the assembly and network complexity of the surface microbiome of Polygonum multiflorum Thunb.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2024)
Article
Food Science & Technology
Gabriele Busetta, Giuliana Garofalo, Salvatore Claps, Maria Teresa Sardina, Elena Franciosi, Antonio Alfonzo, Nicola Francesca, Giancarlo Moschetti, Luca Settanni, Raimondo Gaglio
Summary: This study evaluates the microbial diversity of wooden shelves used for the ripening of PDO Pecorino di Filiano and PGI Canestrato di Moliterno cheeses. The results show a strict correlation between the microbiota of wooden shelves and cheese rinds, indicating the positive role of wooden shelves in the cheese ripening process.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2024)
Article
Food Science & Technology
Massimo Todaro, Giuliana Garofalo, Gabriele Busetta, Riccardo Gannuscio, Ambra Rita Di Rosa, Maria Luisa Scatassa, Cinzia Cardamone, Isabella Mancuso, Elena Franciosi, Fatima Rando, Monica Agnolucci, Vincenzo Chiofalo, Raimondo Gaglio, Luca Settanni
Summary: This study aimed to reduce the production time of PDO Pecorino Siciliano cheese by comparing two cooking methods and assessing their impact on microbiological composition and lactic acid bacteria populations. The results showed that the different cooking methods did not affect the physicochemical characteristics of the cheese, and sensory evaluation confirmed that the modified production protocol did not significantly alter the product characteristics and overall acceptance. Therefore, cooking under hot water proved to be an effective way to reduce the transformation duration while maintaining the typicality of PDO Pecorino Siciliano cheese.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2024)
Article
Food Science & Technology
Yingying Sun, Yana Liu, Weiwei Zhou, Lele Shao, Han Wang, Yijie Zhao, Bo Zou, Xingmin Li, Ruitong Dai
Summary: The study evaluates the effect of Ohmic heating (OH) at various voltage gradients and water bath on microbial inactivation, physicochemical and sensory properties, and microbial flora of pasteurized milk. Results show that OH with higher voltage effectively inactivates microorganisms, slows down lipid oxidation, and maintains sensory quality and amino acids content of milk. The microbial community in milk treated with OH remains relatively stable during storage.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2024)
Article
Food Science & Technology
Minjin Oh, Ana Cevallos-Urena, Byoung Sik Kim
Summary: In this study, two bacteriophages, PECP14 and PECP20, infecting Escherichia coli O157:H7 were isolated and found to be stable under different environmental conditions. These phages exhibited specificity in targeting different host receptors and demonstrated the ability to infect other foodborne pathogens. The efficacy of phage treatment was demonstrated through rapid adsorption and bacterial lysis. Furthermore, purified endolysins derived from these phages showed remarkable bacteriolytic activity not only against E. coli O157:H7 but also against other pathogens. These findings suggest that these phages and their endolysins can be used for biological control of E. coli O157:H7 in various stages of agricultural product production.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2024)
Review
Food Science & Technology
Filippo Marzoli, Michela Bertola, Juliane Pinarelli Fazion, Giulia Cento, Pietro Antonelli, Beatrice Dolzan, Lisa Barco, Simone Belluco
Summary: Insects are a sustainable and protein-rich food source, and Salmonella is a common pathogen in insects. This systematic review aims to collect and evaluate existing studies on the occurrence of Salmonella in crickets and mealworms. Although the number of studies is limited and there are some limitations, this review highlights the importance of obtaining reliable data on the presence of Salmonella in insects, considering the growing market and increased farming scale.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2024)
Review
Food Science & Technology
Lucas Chikhi, Melanie Mancier, Hubert Brugere, Bertrand Lombard, Lyazrhi Faouzi, Laurent Guillier, Nathalie Gnanou Besse
Summary: Listeriosis is a severe foodborne disease with a high mortality rate, mainly caused by L. monocytogenes. The EU regulation sets qualitative or quantitative food safety criteria for L. monocytogenes and recommends the use of EN ISO 11290-1 as the reference detection method. Our study compares alternative certified methods for detecting L. monocytogenes, highlighting the importance of diversifying available detection methods.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2024)
Article
Food Science & Technology
Christina A. M. DeWitt, Kevin A. Nelson, Hyung Joo Kim, David H. Kingsley
Summary: High pressure processing (HPP) is a non-thermal method that can effectively inactivate pathogens. Research has shown that applying high pressure to thawed samples in an ultra-low temperature environment enhances the inactivation of norovirus.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2024)
Article
Food Science & Technology
Suzane Manzini, Thaina Valente Bertozzo, Isabella Neves Aires, Nassarah Jabur Lot Rodrigues, Amanda Bezerra Bertolini, Marcela Alexandrino, Jackieline Sampaio Steinle, Renata Pimentel Bandeira de Melo, Rinaldo Aparecido Mota, Maria Izabel Merino de Medeiros, Virginia Bodelao Richini-Pereira, Vera Claudia Lorenzetti Magalhaes Curci, Simone Baldini Lucheis
Summary: This study detected Toxoplasma gondii DNA in raw bovine milk samples from expansion tanks in small properties located in different cities of the Midwest region of Sa similar to o Paulo, Brazil using PCR. The results showed that the TgNP1 and TgNP2 genes were more efficient in detecting T. gondii DNA, highlighting the importance of raw bovine milk as a potential source of human infections caused by this parasite, and emphasizing the need for proper pasteurization and further understanding of the epidemiology of this protozoan.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2024)
Article
Food Science & Technology
Luca Bolzoni, Mauro Conter, Luca Lamperti, Erika Scaltriti, Marina Morganti, Antonio Poeta, Marco Vecchi, Silvia Paglioli, Alessandra Rampini, Paolo Ramoni, Daniela De Vita, Cristina Bacci, Martina Rega, Laura Andriani, Stefano Pongolini, Silvia Bonardi
Summary: This study assessed the role of equids as carriers of Salmonella and the occurrence of contaminated equid carcasses during the slaughter process. Salmonella was detected in a small percentage of equids' caecal contents, but not in carcass samples. Additionally, a genetic match was found between Salmonella strains from horse caecal contents and human cases, suggesting a link between horse meat consumption and salmonellosis.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2024)
Article
Food Science & Technology
Daria Nowinski, Tomasz Czapka, Irena Maliszewska
Summary: The effect of multiple sublethal doses of non-thermal plasma treatments on phenotypical changes and the reduction in phytopathogenicity of three species of fungi was investigated. The plasma damaged the surface of the fungal hyphae, decreased their dry biomass, and affected the activity of pectinase and xylanase. Furthermore, the plasma treatments increased the germination rate of artificially infected cucumber seeds and resulted in plants with higher biomass and longer roots and stems. However, the reduction in phytopathogenicity was not complete after the multiple plasma treatments.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2024)