Illustrating the interplay between the extracellular matrix and microRNAs

Extracellular Matrix Secretion by Cardiac Fibroblasts

(2013) Mélanie Abonnenc et al.   CIRCULATION RESEARCH

miR-1247 Functions by Targeting Cartilage Transcription Factor SOX9

(2013) Aida Martinez-Sanchez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Downregulation of microRNA let-7a Contributes to the Excessive Expression of Type I Collagen in Systemic and Localized Scleroderma

(2013) K. Makino et al.   JOURNAL OF IMMUNOLOGY

miR-29b moulds the tumour microenvironment to repress metastasis

(2013) Sonia A. Melo et al.   NATURE CELL BIOLOGY

GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression

(2013) Jonathan Chou et al.   NATURE CELL BIOLOGY

Osteoarthritis: A disease of the joint as an organ

(2012) Richard F. Loeser et al.   ARTHRITIS AND RHEUMATISM

Matrigel Basement Membrane Matrix influences expression of microRNAs in cancer cell lines

(2012) Karina J. Price et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Circulating MicroRNAs

(2012) Esther E. Creemers et al.   CIRCULATION RESEARCH

The biology of the extracellular matrix

(2012) Dirk Hubmacher et al.   CURRENT OPINION IN RHEUMATOLOGY

Advances in microRNA experimental approaches to study physiological regulation of gene products implicated in CNS disorders

(2012) Justin M. Long et al.   EXPERIMENTAL NEUROLOGY

Versican 3′-untranslated region (3′-UTR) functions as a ceRNA in inducing the development of hepatocellular carcinoma by regulating miRNA activity

(2012) Ling Fang et al.   FASEB JOURNAL

Comparative profiling of miRNA expression of lung adenocarcinoma cells in two-dimensional and three-dimensional cultures

(2012) Cui Li et al.   GENE

Novel regulatory mechanisms in inflammatory arthritis: a role for microRNA

(2012) Derek Baxter et al.   IMMUNOLOGY AND CELL BIOLOGY

MiRNA-140 is a negative feedback regulator of MMP-13 in IL-1β-stimulated human articular chondrocyte C28/I2 cells

(2012) Zu-jian Liang et al.   INFLAMMATION RESEARCH

Integrin β4 Regulates SPARC Protein to Promote Invasion

(2012) Kristin D. Gerson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyaluronan-CD44v3 Interaction with Oct4-Sox2-Nanog Promotes miR-302 Expression Leading to Self-renewal, Clonal Formation, and Cisplatin Resistance in Cancer Stem Cells from Head and Neck Squamous Cell Carcinoma

(2012) Lilly Y. W. Bourguignon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

The non-coding 3' UTR of CD44 induces metastasis by regulating extracellular matrix functions

(2012) Z. J. Rutnam et al.   JOURNAL OF CELL SCIENCE

Fibronectin and stem cell differentiation - lessons from chondrogenesis

(2012) P. Singh et al.   JOURNAL OF CELL SCIENCE

MicroRNAs, transforming growth factor beta-1, and tissue fibrosis

(2012) Timothy Bowen et al.   JOURNAL OF PATHOLOGY

Macro view of microRNA function in osteoarthritis

(2012) Shigeru Miyaki et al.   Nature Reviews Rheumatology

Secreted microRNAs: a new form of intercellular communication

(2012) Xi Chen et al.   TRENDS IN CELL BIOLOGY

Silencing of microRNA-101 prevents IL-1β-induced extracellular matrix degradation in chondrocytes

(2012) Linghui Dai et al.   ARTHRITIS RESEARCH & THERAPY

MicroRNAs Play a Big Role in Regulating Ovarian Cancer-Associated Fibroblasts and the Tumor Microenvironment

(2012) J. Chou et al.   Cancer Discovery

Endogenous Control of Immunity against Infection: Tenascin-C Regulates TLR4-Mediated Inflammation via MicroRNA-155

(2012) Anna M. Piccinini et al.   Cell Reports

MicroRNA-142-3p regulates TGF-β3-mediated region-dependent chondrogenesis by regulating ADAM9

(2011) Dongkyun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Suppression of hepatic stellate cell activation by microRNA-29b

(2011) Yumiko Sekiya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNA-10b induces glioma cell invasion by modulating MMP-14 and uPAR expression via HOXD10

(2011) Lihua Sun et al.   BRAIN RESEARCH

Identification of MMP-9 specific microRNA expression profile as potential targets of anti-invasion therapy in glioblastoma multiforme

(2011) Wei Yan et al.   BRAIN RESEARCH

miR-340 inhibition of breast cancer cell migration and invasion through targeting of oncoprotein c-Met

(2011) Zheng-sheng Wu et al.   CANCER

MicroRNA-301 Mediates Proliferation and Invasion in Human Breast Cancer

(2011) W. Shi et al.   CANCER RESEARCH

An Extensive MicroRNA-Mediated Network of RNA-RNA Interactions Regulates Established Oncogenic Pathways in Glioblastoma

(2011) Pavel Sumazin et al.   CELL

Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs

(2011) Yvonne Tay et al.   CELL

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

miR-146a–Mediated Extracellular Matrix Protein Production in Chronic Diabetes Complications

(2011) Biao Feng et al.   DIABETES

A non-coding transcript of nephronectin promotes osteoblast differentiation by modulating microRNA functions

(2011) Shao-Chen Lee et al.   FEBS LETTERS

MicroRNA-146a is linked to pain-related pathophysiology of osteoarthritis

(2011) Xin Li et al.   GENE

Regulation of Human Chondrocyte Function through Direct Inhibition of Cartilage Master Regulator SOX9 by MicroRNA-145 (miRNA-145)

(2011) Aida Martinez-Sanchez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles for microRNAs in the regulation of cell adhesion molecules

(2011) S. Valastyan et al.   JOURNAL OF CELL SCIENCE

MiR-133a regulates collagen 1A1: Potential role of miR-133a in myocardial fibrosis in angiotensin II-dependent hypertension

(2011) Giovanna Castoldi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The skeleton: a multi-functional complex organ. The growth plate chondrocyte and endochondral ossification

(2011) E J Mackie et al.   JOURNAL OF ENDOCRINOLOGY

TLR2 Expression Is Regulated by MicroRNA miR-19 in Rheumatoid Fibroblast-like Synoviocytes

(2011) L. Philippe et al.   JOURNAL OF IMMUNOLOGY

miR-31 Is a Broad Regulator of  1-Integrin Expression and Function in Cancer Cells

(2011) K. Augoff et al.   MOLECULAR CANCER RESEARCH

Post-transcriptional up-regulation of miR-21 by type I collagen

(2011) Cui Li et al.   MOLECULAR CARCINOGENESIS

MicroRNA-143 Regulates Human Osteosarcoma Metastasis by Regulating Matrix Metalloprotease-13 Expression

(2011) Mitsuhiko Osaki et al.   MOLECULAR THERAPY

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

(2011) Can Liu et al.   NATURE MEDICINE

Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells

(2011) L Y W Bourguignon et al.   ONCOGENE

MicroRNA-145 Regulates Chondrogenic Differentiation of Mesenchymal Stem Cells by Targeting Sox9

(2011) Bo Yang et al.   PLoS One

Signaling by the Matrix Proteoglycan Decorin Controls Inflammation and Cancer Through PDCD4 and MicroRNA-21

(2011) R. Merline et al.   Science Signaling

Extracellular Matrix Degradation and Remodeling in Development and Disease

(2011) P. Lu et al.   Cold Spring Harbor Perspectives in Biology

MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes

(2010) Nahid Akhtar et al.   ARTHRITIS AND RHEUMATISM

MicroRNA-29, a key regulator of collagen expression in systemic sclerosis

(2010) Britta Maurer et al.   ARTHRITIS AND RHEUMATISM

Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation

(2010) Joanna Stanczyk et al.   ARTHRITIS AND RHEUMATISM

miR-218 inhibits the invasive ability of glioma cells by direct downregulation of IKK-β

(2010) Libing Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

(2010) Markus Hafner et al.   CELL

MicroRNA-488 suppresses cell migration through modulation of the focal adhesion activity during chondrogenic differentiation of chick limb mesenchymal cells

(2010) Jinsoo Song et al.   CELL BIOLOGY INTERNATIONAL

MicroRNA-124 suppresses oral squamous cell carcinoma motility by targeting ITGB1

(2010) Stuart Hunt et al.   FEBS LETTERS

MicroRNA-140 plays dual roles in both cartilage development and homeostasis

(2010) S. Miyaki et al.   GENES & DEVELOPMENT

Increased Expression of a Disintegrin and Metalloprotease-9 in Hepatocellular Carcinoma: Implications for Tumor Progression and Prognosis

(2010) K. Tao et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Up-regulation of MicroRNA-155 in Macrophages Contributes to Increased Tumor Necrosis Factor α (TNFα) Production via Increased mRNA Half-life in Alcoholic Liver Disease

(2010) Shashi Bala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type II Collagen Expression Is Regulated by Tissue-specific miR-675 in Human Articular Chondrocytes

(2010) Katarzyna A. Dudek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyaluronan-CD44 Interaction Promotes c-Src-mediated Twist Signaling, MicroRNA-10b Expression, and RhoA/RhoC Up-regulation, Leading to Rho-kinase-associated Cytoskeleton Activation and Breast Tumor Cell Invasion

(2010) Lilly Y. W. Bourguignon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Repression of Versican Expression by MicroRNA-143

(2010) Xiaobo Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Myocardial Fibrosis by MicroRNAs

(2010) Johann Bauersachs   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Microvesicles: mediators of extracellular communication during cancer progression

(2010) V. Muralidharan-Chari et al.   JOURNAL OF CELL SCIENCE

Differentiation of cardiomyocytes from human embryonic stem cells is accompanied by changes in the extracellular matrix production of versican and hyaluronan

(2010) Christina K. Chan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Tumor-Host Interactions: A Far-Reaching Relationship

(2010) Sandra S. McAllister et al.   JOURNAL OF CLINICAL ONCOLOGY

Mechanisms of skin fibrosis in systemic sclerosis

(2010) Masatoshi JINNIN   JOURNAL OF DERMATOLOGY

Future treatments in systemic sclerosis

(2010) Yoshihide ASANO   JOURNAL OF DERMATOLOGY

Let-7g targets collagen type I α2 and inhibits cell migration in hepatocellular carcinoma

(2010) Junfang Ji et al.   JOURNAL OF HEPATOLOGY

Target mRNA abundance dilutes microRNA and siRNA activity

(2010) Aaron Arvey et al.   Molecular Systems Biology

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

(2010) Laura Poliseno et al.   NATURE

miR-212 and miR-132 are required for epithelial stromal interactions necessary for mouse mammary gland development

(2010) Ahmet Ucar et al.   NATURE GENETICS

Desperately seeking microRNA targets

(2010) Marshall Thomas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Expression of CD44 3′-untranslated region regulates endogenous microRNA functions in tumorigenesis and angiogenesis

(2010) Zina Jeyapalan et al.   NUCLEIC ACIDS RESEARCH

Expression of distinct RNAs from 3′ untranslated regions

(2010) Tim R. Mercer et al.   NUCLEIC ACIDS RESEARCH

Export of microRNAs and microRNA-protective protein by mammalian cells

(2010) Kai Wang et al.   NUCLEIC ACIDS RESEARCH

Collagen regulation of let-7 in pancreatic cancer involves TGF-β1-mediated membrane type 1-matrix metalloproteinase expression

(2010) S Dangi-Garimella et al.   ONCOGENE

MicroRNA miR-93 promotes tumor growth and angiogenesis by targeting integrin-β8

(2010) L Fang et al.   ONCOGENE

Expression of Versican 3′-Untranslated Region Modulates Endogenous MicroRNA Functions

(2010) Daniel Y. Lee et al.   PLoS One

MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses

(2009) Shigeru Miyaki et al.   ARTHRITIS AND RHEUMATISM

Expression of MicroRNA-146a in osteoarthritis cartilage

(2009) Keiichiro Yamasaki et al.   ARTHRITIS AND RHEUMATISM

Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes

(2009) Ginette Tardif et al.   BMC MUSCULOSKELETAL DISORDERS

miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation

(2009) Michela Garofalo et al.   CANCER CELL

MicroRNA Control in the Immune System: Basic Principles

(2009) Changchun Xiao et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

RETRACTED: A Pleiotropically Acting MicroRNA, miR-31, Inhibits Breast Cancer Metastasis

(2009) Scott Valastyan et al.   CELL

MicroRNA-133a Protects Against Myocardial Fibrosis and Modulates Electrical Repolarization Without Affecting Hypertrophy in Pressure-Overloaded Adult Hearts

(2009) Scot J. Matkovich et al.   CIRCULATION RESEARCH

Redefining MicroRNA Targets

(2009) Hervé Seitz   CURRENT BIOLOGY

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

The extracellular matrix in development and morphogenesis: A dynamic view

(2009) Tania Rozario et al.   DEVELOPMENTAL BIOLOGY

Role of CD44s and CD44v6 on human breast cancer cell adhesion, migration, and invasion

(2009) Alaa Afify et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Nephronectin promotes osteoblast differentiation via the epidermal growth factor-like repeats

(2009) Shireen Kahai et al.   FEBS LETTERS

Experimental identification of microRNA targets

(2009) Ulf Andersson Ørom et al.   GENE

Up-regulated microRNA-143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing fibronectin expression

(2009) Xiaoying Zhang et al.   HEPATOLOGY

MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3

(2009) Florin M. Selaru et al.   HEPATOLOGY

Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein

(2009) Li-Fan Lu et al.   IMMUNITY

Hyaluronan-CD44 Interaction with Protein Kinase Cϵ Promotes Oncogenic Signaling by the Stem Cell Marker Nanog and the Production of MicroRNA-21, Leading to Down-regulation of the Tumor Suppressor Protein PDCD4, Anti-apoptosis, and Chemotherapy Resistance in Breast Tumor Cells

(2009) Lilly Y. W. Bourguignon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting of Integrin β1 and Kinesin 2α by MicroRNA 183

(2009) Guorong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

(2009) Mitsuo Kato et al.   NATURE CELL BIOLOGY

MicroRNA MiR-17 retards tissue growth and represses fibronectin expression

(2009) Sze Wan Shan et al.   NATURE CELL BIOLOGY

TGFβ-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3

(2009) B Wang et al.   ONCOGENE

A 3′-Untranslated Region (3′UTR) Induces Organ Adhesion by Regulating miR-199a* Functions

(2009) Daniel Y. Lee et al.   PLoS One

MicroRNA miR-378 Regulates Nephronectin Expression Modulating Osteoblast Differentiation by Targeting GalNT-7

(2009) Shireen Kahai et al.   PLoS One

Inositol phosphatase SHIP1 is a primary target of miR-155

(2009) R. M. O'Connell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals

(2009) F. Bazzoni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Extracellular Matrix: Not Just Pretty Fibrils

(2009) R. O. Hynes   SCIENCE

Shedding microvesicles: artefacts no more

(2009) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Modeling Morphogenesis and Oncogenesis in Three-Dimensional Breast Epithelial Cultures

(2008) Christy Hebner et al.   Annual Review of Pathology-Mechanisms of Disease

Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis

(2008) Joanna Stanczyk et al.   ARTHRITIS AND RHEUMATISM

miRiad Roles for the miR-17-92 Cluster in Development and Disease

(2008) Joshua T. Mendell   CELL

MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy

(2008) Qiang Wang et al.   FASEB JOURNAL

Tumor microenvironment: Modulation by decorin and related molecules harboring leucine-rich tandem motifs

(2008) Silvia Goldoni et al.   INTERNATIONAL JOURNAL OF CANCER

MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators

(2008) G. Gabriely et al.   MOLECULAR AND CELLULAR BIOLOGY

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

Endogenous human microRNAs that suppress breast cancer metastasis

(2008) Sohail F. Tavazoie et al.   NATURE

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

HITS-CLIP yields genome-wide insights into brain alternative RNA processing

(2008) Donny D. Licatalosi et al.   NATURE

The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

(2008) Qihong Huang et al.   NATURE CELL BIOLOGY

The identification of differentially expressed microRNA in osteoarthritic tissue that modulate the production of TNF-α and MMP13

(2008) S.W. Jones et al.   OSTEOARTHRITIS AND CARTILAGE

MicroRNA miR-328 Regulates Zonation Morphogenesis by Targeting CD44 Expression

(2008) Chia-Hui Wang et al.   PLoS One

Prognostic Breast Cancer Signature Identified from 3D Culture Model Accurately Predicts Clinical Outcome across Independent Datasets

(2008) Katherine J. Martin et al.   PLoS One

Integrative MicroRNA and Proteomic Approaches Identify Novel Osteoarthritis Genes and Their Collaborative Metabolic and Inflammatory Networks

(2008) Dimitrios Iliopoulos et al.   PLoS One

MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins

(2008) S. Sengupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

microRNA-138 modulates cardiac patterning during embryonic development

(2008) S. U. Morton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

(2008) E. van Rooij et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA