GLI2 is a novel therapeutic target for metastasis of osteosarcoma

Hedgehog-GLI Signaling Inhibition Suppresses Tumor Growth in Squamous Lung Cancer

(2014) L. Huang et al.   CLINICAL CANCER RESEARCH

Itraconazole and Arsenic Trioxide Inhibit Hedgehog Pathway Activation and Tumor Growth Associated with Acquired Resistance to Smoothened Antagonists

(2013) James Kim et al.   CANCER CELL

Arsenic Trioxide Prevents Osteosarcoma Growth by Inhibition of GLI Transcription via DNA Damage Accumulation

(2013) Shunsuke Nakamura et al.   PLoS One

Vismodegib

(2012) Gillian M. Keating   DRUGS

Targeting hedgehog-GLI-2 pathway in osteosarcoma

(2012) Wen Yang et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma

(2012) Aleksandar Sekulic et al.   NEW ENGLAND JOURNAL OF MEDICINE

RBPJ Is a Novel Target for Rhabdomyosarcoma Therapy

(2012) Hiroko Nagao et al.   PLoS One

TGF- /SMAD/GLI2 Signaling Axis in Cancer Progression and Metastasis

(2011) D. Javelaud et al.   CANCER RESEARCH

Role of GLI2 in the growth of human osteosarcoma

(2011) Hiroko Nagao et al.   JOURNAL OF PATHOLOGY

Hedgehog signalling in gut development, physiology and cancer

(2011) Juanita L. Merchant   JOURNAL OF PHYSIOLOGY-LONDON

Good prognosis of localized osteosarcoma in young patients treated with limb-salvage surgery and chemotherapy

(2011) Marta Hegyi et al.   PEDIATRIC BLOOD & CANCER

Suppression of Osteosarcoma Cell Invasion by Chemotherapy Is Mediated by Urokinase Plasminogen Activator Activity via Up-Regulation of EGR1

(2011) Yukihiro Matsunoshita et al.   PLoS One

The Role of the Hedgehog Signaling Pathway in the Development of Basal Cell Carcinoma and Opportunities for Treatment

(2010) I. Caro et al.   CLINICAL CANCER RESEARCH

Osteosarcoma

(2010) Richard Gorlick et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway

(2010) Elspeth M. Beauchamp et al.   JOURNAL OF CLINICAL INVESTIGATION

Smoothened as a new therapeutic target for human osteosarcoma

(2010) Masataka Hirotsu et al.   Molecular Cancer

Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector

(2010) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumour formation by single fibroblast growth factor receptor 3-positive rhabdomyosarcoma-initiating cells

(2009) M Hirotsu et al.   BRITISH JOURNAL OF CANCER

Bone Repair by Transplantation of hTERT-Immortalized Human Mesenchymal Stem Cells in Mice

(2009) Hiroyuki Nakahara et al.   TRANSPLANTATION

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy

(2009) Suzie J. Scales et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Hedgehog signaling is involved in differentiation of normal colonic tissue rather than in tumor proliferation

(2009) Beate Alinger et al.   VIRCHOWS ARCHIV

Regulation of In Situ to Invasive Breast Carcinoma Transition

(2008) Min Hu et al.   CANCER CELL

Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation

(2008) Rihab Nasr et al.   NATURE MEDICINE

Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features

(2008) Marcel Kool et al.   PLoS One