Generation of MHC class I diversity in primary tumors and selection of the malignant phenotype

Adenovirus expressing β2-microglobulin recovers HLA class I expression and antitumor immunity by increasing T-cell recognition

(2014) A B del Campo et al.   CANCER GENE THERAPY

T Lymphocytes Restrain Spontaneous Metastases in Permanent Dormancy

(2014) I. Romero et al.   CANCER RESEARCH

Effect of tumor cells and tumor microenvironment on NK-cell function

(2014) Massimo Vitale et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immune escape from NY-ESO-1-specific T-cell therapy via loss of heterozygosity in the MHC

(2014) Z K Klippel et al.   GENE THERAPY

Alterations in classical and nonclassical HLA expression in recurrent and progressive HPV-induced usual vulvar intraepithelial neoplasia and implications for immunotherapy

(2014) E.M.G. van Esch et al.   INTERNATIONAL JOURNAL OF CANCER

Tumor MHC Class I Expression Improves the Prognostic Value of T-cell Density in Resected Colorectal Liver Metastases

(2014) S. Turcotte et al.   Cancer Immunology Research

Cancer heterogeneity: implications for targeted therapeutics

(2013) R Fisher et al.   BRITISH JOURNAL OF CANCER

LOH in the HLA Class I Region at 6p21 Is Associated with Shorter Survival in Newly Diagnosed Adult Glioblastoma

(2013) J. T. Yeung et al.   CLINICAL CANCER RESEARCH

Cancer heterogeneity—a multifaceted view

(2013) Felipe De Sousa E Melo et al.   EMBO REPORTS

Immune escape of cancer cells with beta2-microglobulin loss over the course of metastatic melanoma

(2013) Ana B. del Campo et al.   INTERNATIONAL JOURNAL OF CANCER

MHC Class I Antigen Processing and Presenting Machinery: Organization, Function, and Defects in Tumor Cells

(2013) P. Leone et al.   JNCI-Journal of the National Cancer Institute

Suppression of Acquired Docetaxel Resistance in Prostate Cancer through Depletion of Notch- and Hedgehog-Dependent Tumor-Initiating Cells

(2012) Josep Domingo-Domenech et al.   CANCER CELL

Intratumoral electroporation of IL-12 cDNA eradicates established melanomas by Trp2180–188-specific CD8+ CTLs in a perforin/granzyme-mediated and IFN-γ-dependent manner: application of Trp2180–188 peptides

(2012) Jeong-Im Sin et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Implication of the β2-microglobulin gene in the generation of tumor escape phenotypes

(2012) Monica Bernal et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

MHC class I molecules act as tumor suppressor genes regulating the cell cycle gene expression, invasion and intrinsic tumorigenicity of melanoma cells

(2012) Cristina Garrido et al.   CARCINOGENESIS

Exome Sequencing of Prostate Cancer Supports the Hypothesis of Independent Tumour Origins

(2012) Johan Lindberg et al.   EUROPEAN UROLOGY

Alteration of HLA-F and HLA I antigen expression in the tumor is associated with survival in patients with esophageal squamous cell carcinoma

(2012) X. Zhang et al.   INTERNATIONAL JOURNAL OF CANCER

The tumour suppressor Fhit positively regulates MHC class I expression on cancer cells

(2012) Irene Romero et al.   JOURNAL OF PATHOLOGY

Rapid Characterization of Candidate Biomarkers for Pancreatic Cancer Using Cell Microarrays (CMAs)

(2012) Min-Sik Kim et al.   JOURNAL OF PROTEOME RESEARCH

Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation

(2012) Jennifer Landsberg et al.   NATURE

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immunotherapy augments the effect of 5-azacytidine on HPV16-associated tumours with different MHC class I-expression status

(2011) J Šímová et al.   BRITISH JOURNAL OF CANCER

Combined Genetic Inactivation of β2-Microglobulin and CD58 Reveals Frequent Escape from Immune Recognition in Diffuse Large B Cell Lymphoma

(2011) Madhavi Challa-Malladi et al.   CANCER CELL

Immunotherapy eradicates metastases with reversible defects in MHC class I expression

(2011) Cristina Garrido et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Localization and Density of Immune Cells in the Invasive Margin of Human Colorectal Cancer Liver Metastases Are Prognostic for Response to Chemotherapy

(2011) N. Halama et al.   CANCER RESEARCH

Regression of melanoma metastases after immunotherapy is associated with activation of antigen presentation and interferon-mediated rejection genes

(2011) Rafael Carretero et al.   INTERNATIONAL JOURNAL OF CANCER

The escape of cancer from T lymphocytes: immunoselection of MHC class I loss variants harboring structural-irreversible “hard” lesions

(2010) Federico Garrido et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Frequent loss of heterozygosity in the β2-microglobulin region of chromosome 15 in primary human tumors

(2010) Isabel Maleno et al.   IMMUNOGENETICS

Bacillus Calmette-Guerin immunotherapy of bladder cancer induces selection of human leukocyte antigen class I-deficient tumor cells

(2010) Rafael Carretero et al.   INTERNATIONAL JOURNAL OF CANCER

HLA class I antigen and transporter associated with antigen processing downregulation in metastatic lesions of head and neck squamous cell carcinoma as a marker of poor prognosis

(2010) Bandoh   ONCOLOGY REPORTS

Association of HLA class I antigen abnormalities with disease progression and early recurrence in prostate cancer

(2009) Barbara Seliger et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Epigenetic Enhancement of Antigen Processing and Presentation Promotes Immune Recognition of Tumors

(2008) A. F. Setiadi et al.   CANCER RESEARCH

Analysis of HLA class I expression in progressing and regressing metastatic melanoma lesions after immunotherapy

(2008) Rafael Carretero et al.   IMMUNOGENETICS

Malignant and non-malignant lung tissue areas are differentially populated by natural killer cells and regulatory T cells in non-small cell lung cancer

(2007) G. Esendagli et al.   LUNG CANCER