TLR4/PKC-mediated tight junction modulation: A clinical marker of chemotherapy-induced gut toxicity?

Reciprocal Expression and Signaling of TLR4 and TLR9 in the Pathogenesis and Treatment of Necrotizing Enterocolitis

(2014) S. C. Gribar et al.   JOURNAL OF IMMUNOLOGY

Mechanism of IL-1 -Induced Increase in Intestinal Epithelial Tight Junction Permeability

(2014) R. Al-Sadi et al.   JOURNAL OF IMMUNOLOGY

Toll-like receptor 4 increases intestinal permeability through up-regulation of membrane PKC activity in alcoholic steatohepatitis

(2013) Xin Li et al.   ALCOHOL

Activation of the PKC Pathway Stimulates Ovarian Cancer Cell Proliferation, Migration, and Expression of MMP7 and MMP101

(2013) Linah F. Al-Alem et al.   BIOLOGY OF REPRODUCTION

Disruption of ZO-1/claudin-4 interaction in relation to inflammatory responses in methotrexate-induced intestinal mucositis

(2013) Kazuma Hamada et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Induction of intestinal stem cells by R-spondin 1 and Slit2 augments chemoradioprotection

(2013) Wei-Jie Zhou et al.   NATURE

Emerging evidence on the pathobiology of mucositis

(2013) Noor Al-Dasooqi et al.   SUPPORTIVE CARE IN CANCER

Emerging evidence on the pathobiology of mucositis

(2013) Noor Al-Dasooqi et al.   SUPPORTIVE CARE IN CANCER

Chemotherapy-induced mucosal barrier dysfunction

(2013) Hannah R. Wardill et al.   Current Opinion in Supportive and Palliative Care

Suppression of radiation-induced DNA double-strand break repair by MyD88 is accompanied by apoptosis and crypt loss in mouse colon

(2013) X Y Lai et al.   Oncogenesis

Interaction of Clusterin and Matrix Metalloproteinase-9 and Its Implication for Epithelial Homeostasis and Inflammation

(2012) Shinwu Jeong et al.   AMERICAN JOURNAL OF PATHOLOGY

Interleukin-1β-induced barrier dysfunction is signaled through PKC-θ in human brain microvascular endothelium

(2012) Robert R. Rigor et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

In a high-dose melphalan setting, palifermin compared with placebo had no effect on oral mucositis or related patient’s burden

(2012) N Blijlevens et al.   BONE MARROW TRANSPLANTATION

Palifermin is efficacious in recipients of TBI-based but not chemotherapy-based allogeneic hematopoietic stem cell transplants

(2012) J D Goldberg et al.   BONE MARROW TRANSPLANTATION

96. Expression of TLRs in the rat intestine following chemotherapy for cancer

(2012) J. Bowen et al.   BRAIN BEHAVIOR AND IMMUNITY

Chemotherapy-induced gut toxicity: are alterations to intestinal tight junctions pivotal?

(2012) Hannah R. Wardill et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

aPKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formation

(2012) Sandra Iden et al.   JOURNAL OF CELL BIOLOGY

Toll-like receptor 4 signaling in T cells promotes autoimmune inflammation

(2012) J. M. Reynolds et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Methodology for the MASCC/ISOO Mucositis Clinical Practice Guidelines Update

(2012) J. M. Bowen et al.   SUPPORTIVE CARE IN CANCER

Systematic review of agents for the management of gastrointestinal mucositis in cancer patients

(2012) Rachel J. Gibson et al.   SUPPORTIVE CARE IN CANCER

The Expression and the Cellular Distribution of the Tight Junction Proteins Are Altered in Irritable Bowel Syndrome Patients With Differences According to the Disease Subtype

(2011) Nathalie Bertiaux-Vandaële et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Biomarkers of regimen-related mucosal injury

(2011) Rachel J. Gibson et al.   CANCER TREATMENT REVIEWS

Matrix metalloproteinases are possible mediators for the development of alimentary tract mucositis in the dark agouti rat

(2011) Noor Al-Dasooqi et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Irinotecan-induced alterations in intestinal cell kinetics and extracellular matrix component expression in the dark agouti rat

(2011) Noor Al-Dasooqi et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Regulation of Tight Junction Permeability by Intestinal Bacteria and Dietary Components

(2011) Dulantha Ulluwishewa et al.   JOURNAL OF NUTRITION

Severity of doxorubicin-induced small intestinal mucositis is regulated by the TLR-2 and TLR-9 pathways

(2011) Agnieszka Kaczmarek et al.   JOURNAL OF PATHOLOGY

Occludin: One Protein, Many Forms

(2011) P. M. Cummins   MOLECULAR AND CELLULAR BIOLOGY

Effect of Lactobacilli on Paracellular Permeability in the Gut

(2011) Siv Ahrne et al.   Nutrients

Serum levels of NF-κB and pro-inflammatory cytokines following administration of mucotoxic drugs

(2010) Richard M Logan et al.   CANCER BIOLOGY & THERAPY

Zonula Occludens-1 alterations and enhanced intestinal permeability in methotrexate-treated rats

(2010) Kazuma Hamada et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Irinotecan Injures Tight Junction and Causes Bacterial Translocation in Rat

(2010) Toshihiro Nakao et al.   JOURNAL OF SURGICAL RESEARCH

MMP9 modulates tight junction integrity and cell viability in human airway epithelia

(2009) Paola D. Vermeer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Epithelial Tight Junctions in Intestinal Inflammation

(2009) Joerg D. Schulzke et al.   Annals of the New York Academy of Sciences

Roles of ZO-1 and ZO-2 in Establishment of the Belt-like Adherens and Tight Junctions with Paracellular Permselective Barrier Function

(2009) Sachiko Tsukita et al.   Annals of the New York Academy of Sciences

Toll-like receptor 4 participates in gastric mucosal protection through Cox-2 and PGE2

(2009) Yan Zhang et al.   DIGESTIVE AND LIVER DISEASE

Irinotecan-induced mucositis manifesting as diarrhoea corresponds with an amended intestinal flora and mucin profile

(2009) Andrea M. Stringer et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Intestinal barrier function: Molecular regulation and disease pathogenesis

(2009) Katherine R. Groschwitz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Secreted bioactive factors from Bifidobacterium infantis enhance epithelial cell barrier function

(2008) Julia B. Ewaschuk et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Cytokine regulation of tight junctions

(2008) Christopher T. Capaldo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Tight junctions and the modulation of barrier function in disease

(2008) Carola Förster   HISTOCHEMISTRY AND CELL BIOLOGY

Proteolytic processing of chemokines: Implications in physiological and pathological conditions

(2008) M WOLF et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

PKC  regulates occludin phosphorylation and epithelial tight junction integrity

(2008) T. Suzuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletion of toll-like receptor-4 downregulates protein kinase C-ζ and attenuates liver injury in experimental pancreatitis

(2008) Yanhua Peng et al.   SURGERY

Crosstalk of tight junction components with signaling pathways

(2007) Lorenza González-Mariscal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

MyD88 signalling plays a critical role in host defence by controlling pathogen burden and promoting epithelial cell homeostasis during Citrobacter rodentium-induced colitis

(2007) D. L. Gibson et al.   CELLULAR MICROBIOLOGY

The regulation of matrix metalloproteinases and their inhibitors

(2007) I CLARK et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Matrix metalloproteinases as modulators of inflammation

(2007) A MANICONE et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY