Nuclear factor of activated T cells-A transcription factor family as critical regulator in lung and colon cancer

Transcription Factor NFATc2 Controls the Emergence of Colon Cancer Associated with IL-6-Dependent Colitis

(2012) K. Gerlach et al.   CANCER RESEARCH

NFATc1/αA: The other Face of NFAT Factors in Lymphocytes

(2012) Edgar Serfling et al.   Cell Communication and Signaling

Calcineurin/NFATc1 Pathway Contributes to Cell Proliferation in Hepatocellular Carcinoma

(2012) Shuhuai Wang et al.   DIGESTIVE DISEASES AND SCIENCES

An alternative NFAT-activation pathway mediated by IL-7 is critical for early thymocyte development

(2012) Amiya K Patra et al.   NATURE IMMUNOLOGY

Therapeutic opportunities for manipulating TReg cells in autoimmunity and cancer

(2012) Harald von Boehmer et al.   NATURE REVIEWS DRUG DISCOVERY

NFAT1 C-Terminal Domains Are Necessary but Not Sufficient for Inducing Cell Death

(2012) Douglas V. Faget et al.   PLoS One

Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells

(2012) M. Vaeth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-21 in cancer immunotherapy

(2012) Carmine Stolfi et al.   OncoImmunology

NFAT promotes carcinoma invasive migration through glypican-6

(2011) Gary K. Yiu et al.   BIOCHEMICAL JOURNAL

Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth

(2011) Michael Quante et al.   CANCER CELL

NFAT1 transcription factor is central in the regulation of tissue microenvironment for tumor metastasis

(2011) Miriam B. F. Werneck et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Smad7 Expression in T cells Prevents Colitis-Associated Cancer

(2011) A. Rizzo et al.   CANCER RESEARCH

Dephosphorylation of Bcl-10 by calcineurin is essential for canonical NF-κB activation in Th cells

(2011) Stefan Frischbutter et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Restricted Heterochromatin Formation Links NFATc2 Repressor Activity With Growth Promotion in Pancreatic Cancer

(2011) Sandra Baumgart et al.   GASTROENTEROLOGY

Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells

(2011) Hozefa S. Bandukwala et al.   IMMUNITY

The Ca2+-dependent Phosphatase Calcineurin Controls the Formation of the Carma1-Bcl10-Malt1 Complex during T Cell Receptor-induced NF-κB Activation

(2011) Lysann Palkowitsch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NFATc1 affects mouse splenic B cell function by controlling the calcineurin–NFAT signaling network

(2011) Sankar Bhattacharyya et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Involvement of interleukin-21 in the regulation of colitis-associated colon cancer

(2011) Carmine Stolfi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Role of Calcineurin/NFAT in SFRP2 Induced Angiogenesis—A Rationale for Breast Cancer Treatment with the Calcineurin Inhibitor Tacrolimus

(2011) Sharareh Siamakpour-Reihani et al.   PLoS One

Extra-thymically induced regulatory T cells: Do they have potential in disease prevention?

(2011) Carolin Daniel et al.   SEMINARS IN IMMUNOLOGY

Molecular Basis of Calcium Signaling in Lymphocytes: STIM and ORAI

(2010) Patrick G. Hogan et al.   Annual Review of Immunology

An epigenetic chromatin remodeling role for NFATc1 in transcriptional regulation of growth and survival genes in diffuse large B-cell lymphomas

(2010) L. V. Pham et al.   BLOOD

c-Rel is crucial for the induction of Foxp3+regulatory CD4+T cells but not TH17 cells

(2010) Alexander Visekruna et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cutting Edge: CD28 and c-Rel-Dependent Pathways Initiate Regulatory T Cell Development

(2010) K. B. Vang et al.   JOURNAL OF IMMUNOLOGY

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

(2010) Ye Zheng et al.   NATURE

NFAT3 transcription factor inhibits breast cancer cell motility by targeting the Lipocalin 2 gene

(2010) M Fougère et al.   ONCOGENE

Interleukin-11 in Endometrial Adenocarcinoma Is Regulated by Prostaglandin F2α-F-Prostanoid Receptor Interaction via the Calcium-Calcineurin-Nuclear Factor of Activated T Cells Pathway and Negatively Regulated by the Regulator of Calcineurin-1

(2009) Kurt J. Sales et al.   AMERICAN JOURNAL OF PATHOLOGY

Prostaglandin F2α-F-prostanoid receptor regulates CXCL8 expression in endometrial adenocarcinoma cells via the calcium–calcineurin–NFAT pathway

(2009) Kurt J. Sales et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Vascular endothelial growth factor activation of endothelial cells is mediated by early growth response-3

(2009) J.-i. Suehiro et al.   BLOOD

NFAT signalling is a novel target of oncogenic BRAF in metastatic melanoma

(2009) R J Flockhart et al.   BRITISH JOURNAL OF CANCER

Inflammation and Cancer: IL-6 and STAT3 Complete the Link

(2009) Jacqueline Bromberg et al.   CANCER CELL

gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis

(2009) Julia Bollrath et al.   CANCER CELL

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL

A Key Regulatory Role of the Transcription Factor NFATc2 in Bronchial Adenocarcinoma via CD8+ T Lymphocytes

(2009) J. H. Maxeiner et al.   CANCER RESEARCH

SnapShot: Ca2+-Calcineurin-NFATSignaling

(2009) Gerald R. Crabtree et al.   CELL

Differential functions of genes regulated by VEGF-NFATc1 signaling pathway in the migration of pulmonary valve endothelial cells

(2009) Gun Hyuk Jang et al.   FEBS LETTERS

NFAT-Induced Histone Acetylation Relay Switch Promotes c-Myc-Dependent Growth in Pancreatic Cancer Cells

(2009) Alexander Köenig et al.   GASTROENTEROLOGY

Nuclear Factor-κB Modulates Regulatory T Cell Development by Directly Regulating Expression of Foxp3 Transcription Factor

(2009) Meixiao Long et al.   IMMUNITY

Development of Foxp3+ Regulatory T Cells Is Driven by the c-Rel Enhanceosome

(2009) Qingguo Ruan et al.   IMMUNITY

Regulation of T-cell tolerance by calcium/NFAT signaling

(2009) Ian Baine et al.   IMMUNOLOGICAL REVIEWS

Sumoylation of the Transcription Factor NFATc1 Leads to Its Subnuclear Relocalization and Interleukin-2 Repression by Histone Deacetylase

(2009) Arnab Nayak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Colitis-associated cancer: the role of T cells in tumor development

(2009) Maximilian J. Waldner et al.   Seminars in Immunopathology

Suppressing NFAT Increases VEGF Signaling in Hemangiomas

(2008) Lisette M. Acevedo et al.   CANCER CELL

Regulation of Gut Inflammation and Th17 Cell Response by Interleukin-21

(2008) Daniele Fina et al.   GASTROENTEROLOGY

CHP2 Activates the Calcineurin/Nuclear Factor of Activated T Cells Signaling Pathway and Enhances the Oncogenic Potential of HEK293 Cells

(2008) Guo-Dong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The transcription factor NFATc2 controls IL-6–dependent T cell activation in experimental colitis

(2008) Benno Weigmann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dual Roles for NFAT Transcription Factor Genes as Oncogenes and Tumor Suppressors

(2008) B. K. Robbs et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of Transcription Factor NFAT by ADP-Ribosylation

(2008) O. A. Olabisi et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of NFAT by poly(ADP-ribose) polymerase activity in T cells

(2008) Rut Valdor et al.   MOLECULAR IMMUNOLOGY

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

(2008) Masatsugu Oh-hora et al.   NATURE IMMUNOLOGY

NFAT Binding and Regulation of T Cell Activation by the Cytoplasmic Scaffolding Homer Proteins

(2008) G. N. Huang et al.   SCIENCE

TCDD induces cell migration via NFATc1/ATX-signaling in MCF-7 cells

(2008) Anja Seifert et al.   TOXICOLOGY LETTERS