Remarkable inhibition of mTOR signaling by the combination of rapamycin and 1,4-phenylenebis(methylene)selenocyanate in human prostate cancer cells

Methylseleninic acid downregulates hypoxia-inducible factor-1α in invasive prostate cancer

(2011) Indu Sinha et al.   INTERNATIONAL JOURNAL OF CANCER

Chemopreventive mechanisms of α-keto acid metabolites of naturally occurring organoselenium compounds

(2010) John T. Pinto et al.   AMINO ACIDS

1,4-Phenylenebis(Methylene)Selenocyanate, but Not Selenomethionine, Inhibits Androgen Receptor and Akt Signaling in Human Prostate Cancer Cells

(2010) N. D. Facompre et al.   Cancer Prevention Research

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Suppression of mTOR via Akt-dependent and -independent mechanisms in selenium-treated colon cancer cells: involvement of AMPK 1

(2010) Y.-K. Lee et al.   CARCINOGENESIS

Activation of the mammalian target of rapamycin signalling pathway in prostate cancer and its association with patient clinicopathological characteristics

(2009) Bo Dai et al.   BJU INTERNATIONAL

Selenium enrichment of broccoli sprout extract increases chemosensitivity and apoptosis of LNCaP prostate cancer cells

(2009) Rizky Abdulah et al.   BMC CANCER

mTOR Complex 2 Is Required for the Development of Prostate Cancer Induced by Pten Loss in Mice

(2009) David A. Guertin et al.   CANCER CELL

Inhibition of Tumor Growth Progression by Antiandrogens and mTOR Inhibitor in a Pten-Deficient Mouse Model of Prostate Cancer

(2009) W. Zhang et al.   CANCER RESEARCH

Potential Stages for Prostate Cancer Prevention with Selenium: Implications for Cancer Survivors

(2009) N. Facompre et al.   CANCER RESEARCH

TORC-Specific Phosphorylation of Mammalian Target of Rapamycin (mTOR): Phospho-Ser2481 Is a Marker for Intact mTOR Signaling Complex 2

(2009) J. Copp et al.   CANCER RESEARCH

Optimal targeting of the mTORC1 kinase in human cancer

(2009) Heidi A Lane et al.   CURRENT OPINION IN CELL BIOLOGY

Synthesis and antitumor properties of selenocoxib-1 against rat prostate adenocarcinoma cells

(2009) Dhimant Desai et al.   INTERNATIONAL JOURNAL OF CANCER

mTOR Ser-2481 Autophosphorylation Monitors mTORC-specific Catalytic Activity and Clarifies Rapamycin Mechanism of Action

(2009) Ghada A. Soliman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of Selenite and Genistein on G2/M Cell Cycle Arrest and Apoptosis in Human Prostate Cancer Cells

(2009) Rui Zhao et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Mammalian Target of Rapamycin: Discovery of Rapamycin Reveals a Signaling Pathway Important for Normal and Cancer Cell Growth

(2009) James J. Gibbons et al.   SEMINARS IN ONCOLOGY

Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models

(2009) Nancy Lee et al.   BMC Pharmacology & Toxicology

Preclinicalversusclinical drug combination studies

(2008) Ting-Chao Chou   LEUKEMIA & LYMPHOMA

Synergistic effect of a novel antiandrogen, VN/124-1, and signal transduction inhibitors in prostate cancer progression to hormone independence in vitro

(2008) A. Schayowitz et al.   MOLECULAR CANCER THERAPEUTICS

Effects of Naturally Occurring and Synthetic Organoselenium Compounds on Protein Profiling in Androgen Responsive and Androgen Independent Human Prostate Cancer Cells

(2008) Raghu Sinha et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Regulation of androgen receptor transcriptional activity by rapamycin in prostate cancer cell proliferation and survival

(2008) Y Wang et al.   ONCOGENE