IGF binding protein-6 expression in vascular endothelial cells is induced by hypoxia and plays a negative role in tumor angiogenesis

Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling

(2010) S. Rey et al.   CARDIOVASCULAR RESEARCH

Insulin-like growth factor binding protein-6 (IGFBP-6) interacts with DNA-end binding protein Ku80 to regulate cell fate

(2010) Cristiana Iosef et al.   CELLULAR SIGNALLING

Cross-talk between MAP kinase pathways is involved in IGF-independent, IGFBP-6-induced Rh30 rhabdomyosarcoma cell migration

(2010) Ping Fu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

IGFBP-6 plays a role as an oncosuppressor gene in NPC pathogenesis through regulating EGR-1 expression

(2010) Yuan-Sung Kuo et al.   JOURNAL OF PATHOLOGY

Hypoxia-Regulated Angiogenic Inhibitors

(2010) Angela Messmer-Blust et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Molecular and functional characterization of two distinct IGF binding protein-6 genes in zebrafish

(2009) Xianlei Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Response Gene to Complement 32, a Novel Hypoxia-Regulated Angiogenic Inhibitor

(2009) Xiaojin An et al.   CIRCULATION

RGS5, a Hypoxia-inducible Apoptotic Stimulator in Endothelial Cells

(2009) Yi Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease

(2009) Peter Fraisl et al.   NATURE REVIEWS DRUG DISCOVERY

The role of hypoxia-inducible factors in tumorigenesis

(2008) E B Rankin et al.   CELL DEATH AND DIFFERENTIATION

Identification of IGFBP-6 as an effector of the tumor suppressor activity of SEMA3B

(2008) N Koyama et al.   ONCOGENE

A Functional Nuclear Localization Signal in Insulin-Like Growth Factor Binding Protein-6 Mediates Its Nuclear Import

(2007) Cristiana Iosef et al.   ENDOCRINOLOGY