Leukemia stem cells

Clinical evaluation of cellular immunotherapy in acute myeloid leukaemia

(2011) Evelien L. J. Smits et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Therapeutic Advances in Acute Myeloid Leukemia

(2011) Alan Burnett et al.   JOURNAL OF CLINICAL ONCOLOGY

Leukemia Stem Cells and Microenvironment: Biology and Therapeutic Targeting

(2011) Marina Y. Konopleva et al.   JOURNAL OF CLINICAL ONCOLOGY

Evolution of human BCR–ABL1 lymphoblastic leukaemia-initiating cells

(2011) Faiyaz Notta et al.   NATURE

In Search of CML Stem Cells’ Deadly Weakness

(2011) Francesca Pellicano et al.   Current Hematologic Malignancy Reports

Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34- fraction

(2010) D. C. Taussig et al.   BLOOD

Differential survival of AML subpopulations in NOD/SCID mice

(2010) Mario Schubert et al.   EXPERIMENTAL HEMATOLOGY

AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3

(2010) M Wunderlich et al.   LEUKEMIA

Genetic variegation of clonal architecture and propagating cells in leukaemia

(2010) Kristina Anderson et al.   NATURE

N-Cadherin is expressed on human hematopoietic progenitor cells and mediates interaction with human mesenchymal stromal cells

(2010) Frederik Wein et al.   Stem Cell Research

The leukemic stem cell niche: current concepts and therapeutic opportunities

(2009) S. W. Lane et al.   BLOOD

Monoclonal Antibody-Mediated Targeting of CD123, IL-3 Receptor α Chain, Eliminates Human Acute Myeloid Leukemic Stem Cells

(2009) Liqing Jin et al.   Cell Stem Cell

Interleukin-2 receptor alpha-chain (CD25) expression on leukaemic blasts is predictive for outcome and level of residual disease in AML

(2009) Monique Terwijn et al.   EUROPEAN JOURNAL OF CANCER

Aldehyde dehydrogenase activity among primary leukemia cells is associated with stem cell features and correlates with adverse clinical outcomes

(2009) Dan Ran et al.   EXPERIMENTAL HEMATOLOGY

Co-culture with mesenchymal stromal cells increases proliferation and maintenance of haematopoietic progenitor cells

(2009) Thomas Walenda et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Improved T and B cell recovery by the transfer of slowly dividing human hematopoietic stem cells

(2009) Mario Vitacolonna et al.   LEUKEMIA RESEARCH

IFNα activates dormant haematopoietic stem cells in vivo

(2009) Marieke A. G. Essers et al.   NATURE

The Increasing Complexity of the Cancer Stem Cell Paradigm

(2009) J. M. Rosen et al.   SCIENCE

Dual SP/ALDH Functionalities Refine the Human Hematopoietic Lin−CD34+CD38−Stem/Progenitor Cell Compartment

(2009) Olivier Pierre-Louis et al.   STEM CELLS

Acute myeloid leukemia stem cells: seek and destroy

(2009) Gail J Roboz et al.   Expert Review of Hematology

Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells

(2008) D. C. Taussig et al.   BLOOD

Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data

(2008) D. C. Hassane et al.   BLOOD

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML

(2008) Z. Zeng et al.   BLOOD

In Childhood Acute Lymphoblastic Leukemia, Blasts at Different Stages of Immunophenotypic Maturation Have Stem Cell Properties

(2008) Christoph le Viseur et al.   CANCER CELL

CD34+CD38+CD19+ as well as CD34+CD38−CD19+ cells are leukemia-initiating cells with self-renewal capacity in human B-precursor ALL

(2008) Y Kong et al.   LEUKEMIA

PML targeting eradicates quiescent leukaemia-initiating cells

(2008) Keisuke Ito et al.   NATURE

Initiating and Cancer-Propagating Cells in TEL-AML1-Associated Childhood Leukemia

(2008) D. Hong et al.   SCIENCE

Identification of a Small Subpopulation of Candidate Leukemia-Initiating Cells in the Side Population of Patients with Acute Myeloid Leukemia

(2008) Bijan Moshaver et al.   STEM CELLS