Acute myeloid leukemia stem cells: seek and destroy

The leukemic stem cell niche: current concepts and therapeutic opportunities

(2009) S. W. Lane et al.   BLOOD

Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells

(2009) Masayoshi Kobune et al.   CANCER SCIENCE

CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

(2009) Ravindra Majeti et al.   CELL

Monoclonal Antibody-Mediated Targeting of CD123, IL-3 Receptor α Chain, Eliminates Human Acute Myeloid Leukemic Stem Cells

(2009) Liqing Jin et al.   Cell Stem Cell

Notch Inhibitors as a New Tool in the War on Cancer: A Pathway to Watch

(2009) Benjamin Purow   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia

(2009) Chen Zhao et al.   NATURE

Multilevel targeting of hematopoietic stem cell self-renewal, differentiation and apoptosis for leukemia therapy

(2009) Asterios S. Tsiftsoglou et al.   PHARMACOLOGY & THERAPEUTICS

Dysregulated gene expression networks in human acute myelogenous leukemia stem cells

(2009) R. Majeti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting Stem Cells-Clinical Implications for Cancer Therapy

(2009) Lan Tu et al.   Current Stem Cell Research & Therapy

Can we finally target the leukemic stem cells?

(2008) Craig T. Jordan   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML

(2008) Z. Zeng et al.   BLOOD

NF-κB and cancer—identifying targets and mechanisms

(2008) Willscott E Naugler et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Targeting the leukemic stem cell: the Holy Grail of leukemia therapy

(2008) N Misaghian et al.   LEUKEMIA

Phase I clinical study of diphtheria toxin-interleukin 3 fusion protein in patients with acute myeloid leukemia and myelodysplasia

(2008) Arthur Frankel et al.   LEUKEMIA & LYMPHOMA

Intrinsic and extrinsic control of haematopoietic stem-cell self-renewal

(2008) Leonard I. Zon   NATURE

Initiating and Cancer-Propagating Cells in TEL-AML1-Associated Childhood Leukemia

(2008) D. Hong et al.   SCIENCE

Leukemic Cells Create Bone Marrow Niches That Disrupt the Behavior of Normal Hematopoietic Progenitor Cells

(2008) Angela Colmone et al.   SCIENCE

Targeting FLT3 for the Treatment of Leukemia

(2008) Donald Small   SEMINARS IN HEMATOLOGY

Leukemia Stem Cells in Acute Myeloid Leukemia

(2008) Wai-In Chan et al.   SEMINARS IN ONCOLOGY

Identification of a Small Subpopulation of Candidate Leukemia-Initiating Cells in the Side Population of Patients with Acute Myeloid Leukemia

(2008) Bijan Moshaver et al.   STEM CELLS