Article
Biochemistry & Molecular Biology
Yuan Gao, Xiaochen Gong, Shuang Yu, Zheng Jin, Qicheng Ruan, Chunjing Zhang, Kai Zhao
Summary: The study found that N-2-Hydroxypropyl trimethyl ammonium chloride chitosan/N, O-carboxymethyl chitosan nanoparticles (N-2-HACC/CMCS NPs) showed good immunogenicity and no toxicity as a universal vaccine adjuvant/delivery system. The prepared N-2-HACC/OVA/CMCS NPs induced higher levels of antibodies and immune responses in mice, suggesting their potential in enhancing humoral, cellular, and mucosal immune responses.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Xuepeng Yu, Yueyue Yang, Qing Liu, Zhengyu Jin, Aiquan Jiao
Summary: CEO-loaded chitosan nanoparticles (CNs) were prepared and embedded in HPMC/HPS blends to improve the properties of the formed films. The reinforced nanocomposite films showed enhanced mechanical and barrier properties, as well as sustained release of CEO with antioxidant and antimicrobial effects. These nanocomposite films have great potential for food preservation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Ling Ding, Zhao Liu, Shen Song, Mohamed Aamer Abubaker, Lele Chen, Jipeng Shi, Zengjie Fan, Ji Zhang
Summary: HACC, synthesized by reacting chitosan with glycidyl trimethylammonium chloride, forms a non-Newtonian pseudoplastic fluid in solution, with thixotropy highly dependent on concentration changes. Dynamic viscoelasticity tests show that HACC exhibits both viscous behavior similar to a fluid and elastic properties of weak gel.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Juliana Domingues dos Santos Carvalho, Renata Santos Rabelo, Miriam Dupas Hubinger
Summary: The study investigated the thermal and rheological properties of methylcellulose and hydroxypropyl methylcellulose hydrogels with the addition of chitosan. The results indicated that the addition of chitosan allowed these polymers to form gels at lower temperatures, which could benefit the processing of oil carrier systems under milder thermal conditions.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Materials Science, Multidisciplinary
Xuepeng Yu, Qing Liu, Zhengyu Jin, Aiquan Jiao
Summary: Edible films made from chitosan nanoparticles (CSNPs) can effectively reduce environmental pollution caused by non-degradable plastics. The addition of CSNPs improved the properties of the composite films, including hydrophobicity, thermal stability, mechanical properties, and permeability. The size of the CSNPs played a significant role in determining the performance of the films, with smaller CSNPs showing better enhancement in barrier properties and mechanical properties.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Chemistry, Applied
Yang Zhou, Zhenghao Zhai, Yimin Yao, John C. Stant, Sarah L. Landrum, Michael J. Bortner, Charles E. Frazier, Kevin J. Edgar
Summary: Polysaccharide-based Schiff base hydrogels prepared by reacting oxidized hydroxypropyl cellulose (Ox-HPC) with carboxymethyl chitosan (CMCS) exhibit pH-responsive, injectable, and self-healing properties. The reversible nature of the imine bonds allows for an injectable and self-healing hydrogel. The incorporation of the model amine-containing drug phenylalanine within the hydrogel showed pH sensitivity, releasing faster in the extracellular space around tumors (pH 6.8) compared to normal tissues (pH 7.4).
CARBOHYDRATE POLYMERS
(2023)
Article
Biochemistry & Molecular Biology
Lin Yue, Min Wang, Imran Mahmood Khan, Jianguo Xu, Chifang Peng, Zhouping Wang
Summary: In this study, cinnamic acid conjugated hydroxypropyl chitosan derivatives with different degrees of substitution were successfully synthesized and showed good antibacterial activity against Staphylococcus aureus and Escherichia coli. The derivatives exhibited better water solubility than chitosan and had a significant inhibitory effect on biofilm formation. These results suggest the potential applicability of these derivatives in the treatment of biofilm-associated infections.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Jilong Cao, Guanghua He, Xiaoqing Ning, Cheng Wang, Lihong Fan, Yihua Yin, Weiquan Cai
Summary: A facile approach was developed for the preparation of dual self-healing and adsorption hydrogel through HPCS, PAM, and PVA. The hydrogel exhibited high adsorption capacity and mechanical strength, making it a promising candidate for long-life adsorbents.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Food Science & Technology
Ata Aditya Wardana, Laras Putri Wigati, Fumina Tanaka, Fumihiko Tanaka
Summary: The effect of incorporating chitosan nanoparticles into hydroxypropyl cellulose bionanocomposite films was investigated. The results showed that the addition of nanofiller improved the functional properties and exhibited antifungal activity.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Jinwen Liu, Shuyan Li, Wuliji Ao, Yongji Li, Yingge Xiao, Meirong Bai
Summary: This study aimed to improve the permeability and solubility of aprepitant to enhance its oral bioavailability. Hydroxypropyl chitosan was used as a stabilizer for the nanosuspension, resulting in a higher solubility compared to aprepitant. The nanosuspension also showed improved permeability in Caco-2 cells.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2022)
Article
Materials Science, Multidisciplinary
Chunmiao Fu, Zheng Jin, Kai Zhao
Summary: Long-term or excessive exposure to UV light can cause various skin damages, but the N-2-HACC/HA/EA/PC composite hydrogel developed in this study can effectively protect the skin from UV-induced injuries and has multiple functions such as antioxidant and anti-inflammatory activities.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Food Science & Technology
Min Wang, Lin Yue, Lingyu Zhao, Imran Mahmood Khan, Yin Zhang, Zhouping Wang
Summary: Chitosan derivatives were chemically modified and used to synthesize nanoparticles, which were then applied to stabilize oil-in-water emulsions. The nanoparticles exhibited good properties and the emulsions showed promising stability and potential for bioactive compound delivery.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Lin Yue, Zhouping Wang, Meihong Zheng, Min Wang, Imran Mahmood Khan, Xiaowei Ding, Yin Zhang
Summary: In this study, Hydroxypropyl chitosan was used as a carrier of the photosensitizer chlorin e6 to develop a photodynamic antibacterial agent with good water solubility, high biocompatibility, and antibacterial activity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Zhi Zhao, Jinyu Han, Shangen Xu, Zheng Jin, Tan Hui Yin, Kai Zhao
Summary: This report presents the encapsulation of amoxicillin in N-2-Hydroxypropyl trimethyl ammonium chloride chitosan and N,O-carboxymethyl chitosan nanoparticles for biomedical applications. The synthesized nanoparticles demonstrated sustained drug release, good cytocompatibility and broad-spectrum antimicrobial activity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Polymer Science
Yanan Sang, Pengpai Miao, Tao Chen, Yuan Zhao, Linfeng Chen, Yayang Tian, Xiaobing Han, Jie Gao
Summary: The incorporation of graphene oxide (GO) into a polymeric drug carrier enhances loading efficiency, reduces the initial burst, and improves the controllability of drug release. The study shows that adjusting the content of GO and the polymer can affect drug loading and encapsulation efficiency.
Article
Cell Biology
Tian-Li Duan, Han Jiao, Guang-Jun He, Yong-Bin Yan
Review
Cell Biology
Yong-Bin Yan
Summary: DDR is a coordinated network of cellular processes involving detection, signaling, and repair of DNA damage. Adjusting RNA fate through modulating polyadenylation and deadenylation plays a crucial role in reshaping gene expression profile to deal with DNA damage.
WILEY INTERDISCIPLINARY REVIEWS-RNA
(2021)
Article
Biochemistry & Molecular Biology
Kai-Jie Wang, Xiao-Yan Liao, Kunxia Lin, Yi-Bo Xi, Sha Wang, Xiu-Hua Wan, Yong-Bin Yan
Summary: A novel F30S mutation in gamma S-crystallin was identified in a Chinese family with ADCC, leading to nuclear cataract phenotype. The mutation destabilized the protein, altered its unfolding process, and disrupted cooperativity between domains during unfolding, providing new insights into the molecular mechanism underlying ADCC caused by mutations in beta/gamma-crystallins.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Multidisciplinary Sciences
Boqiao Fu, Yingjie Li, Shaoyong Peng, Xiaolin Wang, Jingying Hu, Long Lv, Caifen Xia, Dai Lu, Caiqin Qin
Summary: A new glucopyranosyl-conjugated benzyl derivative containing a [1,2,3]-triazole linker was synthesized and showed potent antiproliferative activity against colorectal cancer cells, inducing apoptotic cell death.
ROYAL SOCIETY OPEN SCIENCE
(2021)
Article
Oncology
Xiao-Hui Song, Xiao-Yan Liao, Xu-Ying Zheng, Jia-Qian Liu, Zhe-Wei Zhang, Li-Na Zhang, Yong-Bin Yan
Summary: Cancer cells reprogram gene expression profiles to support continuous growth, proliferation, and metastasis. Dysregulation of the human deadenylases Ccr4a/b and Caf1a/b is observed in various types of cancers, and depletion of these enzymes inhibits cell proliferation and tumorigenicity. Targeting global RNA metabolism may offer a potential novel strategy for cancer treatment.
Article
Biochemistry & Molecular Biology
Ying Kong, Chongyang Mao, Shu Li, Yan Xie, Xiao-Lian Zhang, Boqiao Fu
Summary: Six novel imidazolinone derivatives were synthesized, and compound 4b, containing 5-para-methoxy-phenylidene and 2-thioalkylation terminal substitution, exhibited the strongest anti-HCV activity and the lowest cytotoxicity. The selectivity index (SI=CC50/IC50) of 4b was determined to be 36, indicating its high selectivity towards HCV.
CHEMISTRY & BIODIVERSITY
(2022)
Article
Cell & Tissue Engineering
Danni Lyu, Lifang Zhang, Zhenwei Qin, Shuang Ni, Jiayong Li, Bing Lu, Shengjie Hao, Qiaomei Tang, Houfa Yin, Zhijian Chen, Yong-Bin Yan, Junfeng Ji, Jiliang He, Andras Nagy, Qiuli Fu, Ke Yao
Summary: This study established a human congenital cataract in vitro model by differentiating patient-specific induced pluripotent stem cells (iPSCs) into regenerated lenses, which recapitulated the clinical manifestations and protein aggregation characteristics of patients' cataracts.
NPJ REGENERATIVE MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Xinyu Ma, Caijing Lu, Yuting Chen, Shulin Li, Ningjia Ma, Xuan Tao, Ying Li, Jing Wang, Min Zhou, Yong-Bin Yan, Pilong Li, Kartoosh Heydari, Haiteng Deng, Min Zhang, Cong Yi, Liang Ge
Summary: In this study, the researchers identified CCT2 as an autophagy receptor that regulates the clearance of aggregation-prone proteins in cells and mouse brains. CCT2 selectively associates with aggregation-prone proteins and interacts with autophagosome marker ATG8s. Furthermore, CCT2 specifically promotes the autophagic degradation of solid protein aggregates, independent of other ubiquitin-binding receptors or chaperone-mediated autophagy.
Article
Chemistry, Multidisciplinary
Feihong Lu, Yi Chen, Boqiao Fu, Shigui Chen, Lu Wang
Summary: A stimuli-responsive supramolecular polymer network has been created using host-guest interactions, and its dissociation through the addition of competitive molecules and heating results in significant changes in its physical properties.
CHINESE CHEMICAL LETTERS
(2022)
Article
Chemistry, Organic
Chongyang Mao, Zhen Cao, Boqiao Fu, Shengcheng Wang, Haowei Chen, Caifen Xia, Xinliang Hu, Xinyuan Huang, Caiqin Qin
Summary: A series of 2-thio-imidazolidinone derivatives with aryl group modifications at the end of the five-carbon side chain were synthesized. The target compounds were obtained in higher yield (77-95%) and shorter reaction time under the assistance of microwave heating at 100 degrees Celsius for 2 hours.
SYNTHETIC COMMUNICATIONS
(2022)
Article
Thermodynamics
Caifen Xia, Boqiao Fu, Jian-Cheng Jin
Summary: This study investigated the effect of Nd(III) on mitochondrial metabolism and evaluated its toxicology effect, using microcalorimetry assays to determine thermokinetic parameters. The results showed that Nd(III) affected mitochondrial energy metabolism depending on its concentration, with low levels promoting activity and high levels inhibiting it. The study also assessed the impact of Nd(III) on the respiratory chain of mitochondria, which aligned with the microcalorimetry results. These findings deepen our understanding of the mechanism of Nd(III) in mitochondrial metabolic processes and provide insights for the biosafety of rare-earth elements.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Boqiao Fu, Zhen Cao, Boying Wu, Chongyang Mao, Caiqin Qin, Shigui Chen
Summary: The synthesis of MFHP from Claisen salts and formaldehyde in water is developed, providing a novel strategy to overcome the shortcomings of MFA and improve storage life and cost efficiency.
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
(2022)
Article
Biochemistry & Molecular Biology
Xin-Hang Zhang, Xiang-Jun Chen, Yong-Bin Yan
Summary: This study uncovered the molecular mechanism of cytosolic CK recruitment by the mitotic apparatus, showing that Fam96b acts as a scaffold protein to coordinate ATP supply and Fe/S cluster homeostasis during mitosis. Depletion of Fam96b or CKB resulted in mitotic defects, impaired cell proliferation, increased cell death, and aberrant cell cycle progression.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
(2023)
Review
Microbiology
Yuelin Guan, Yan Wang, Xudong Fu, Guannan Bai, Xue Li, Jianhua Mao, Yongbin Yan, Lidan Hu
Summary: Stress granules are RNA granules induced by stress and are evolutionarily conserved. They act as a self-protection mechanism during stress responses. Viral infections can trigger cellular stress responses, potentially interacting with stress granule formation. This review summarizes the role of stress granules in viral infection, particularly focusing on SARS-CoV-2. Additionally, it outlines drugs targeting stress granules and their potential effectiveness against SARS-CoV-2.
FRONTIERS IN MICROBIOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Xiao-Yan Liao, Yong-Bin Yan
Summary: In eukaryotic cells, deadenylation is achieved by deadenylases, which specifically degrade poly(A) or oligo(A) at the 3'-end of RNAs. Deadenylases play important roles in RNA metabolism, transcription regulation, translation efficiency, stress response, immune response, genome integrity, and stem cell differentiation. They are also involved in diverse cellular processes and associated with various diseases. The regulation of deadenylases involves a complex network of cis-acting elements, RNA-binding proteins, and post-translational modifications, which modulate RNA homeostasis and gene expression.
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
(2023)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
