Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity
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Title
Preventing AID, a physiological mutator, from deleterious activation: regulation of the genomic instability that is associated with antibody diversity
Authors
Keywords
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Journal
INTERNATIONAL IMMUNOLOGY
Volume 22, Issue 4, Pages 227-235
Publisher
Oxford University Press (OUP)
Online
2010-03-06
DOI
10.1093/intimm/dxq023
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- Activation-Induced Cytidine Deaminase Expression and Activity in the Absence of Germinal Centers: Insights into Hyper-IgM Syndrome
- (2009) M. Kuraoka et al. JOURNAL OF IMMUNOLOGY
- Different isoforms of the B-cell mutator activation-induced cytidine deaminase are aberrantly expressed in BCR–ABL1-positive acute lymphoblastic leukemia patients
- (2009) I Iacobucci et al. LEUKEMIA
- AID protein expression in chronic lymphocytic leukemia/small lymphocytic lymphoma is associated with poor prognosis and complex genetic alterations
- (2009) Mona Leuenberger et al. MODERN PATHOLOGY
- AID Produces DNA Double-Strand Breaks in Non-Ig Genes and Mature B Cell Lymphomas with Reciprocal Chromosome Translocations
- (2009) Davide F. Robbiani et al. MOLECULAR CELL
- Mechanisms promoting translocations in editing and switching peripheral B cells
- (2009) Jing H. Wang et al. NATURE
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- (2009) Nidhi Bhutani et al. NATURE
- HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation
- (2009) Seok-Rae Park et al. NATURE IMMUNOLOGY
- B cell–specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers
- (2009) Thinh Huy Tran et al. NATURE IMMUNOLOGY
- AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination
- (2009) Maki Kobayashi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2009) Hwei-Ling Cheng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination
- (2009) Tomomitsu Doi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2008) Grace Teng et al. IMMUNITY
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- Regulation of histone H4 acetylation by transcription factor E2A in Ig gene conversion
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- Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression
- (2008) Toshiyuki Morisawa et al. INTERNATIONAL JOURNAL OF CANCER
- Impact of Phosphorylation and Phosphorylation-null Mutants on the Activity and Deamination Specificity of Activation-induced Cytidine Deaminase
- (2008) Phuong Pham et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Conformational Variants of Duplex DNA Correlated with Cytosine-rich Chromosomal Fragile Sites
- (2008) Albert G. Tsai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- AID expression levels determine the extent ofcMyconcogenic translocations and the incidence of B cell tumor development
- (2008) Makiko Takizawa et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Regulation of class switch recombination and somatic mutation by AID phosphorylation
- (2008) Kevin M. McBride et al. JOURNAL OF EXPERIMENTAL MEDICINE
- miR-181b negatively regulates activation-induced cytidine deaminase in B cells
- (2008) Virginia G. de Yébenes et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Proteasomal degradation restricts the nuclear lifespan of AID
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- Two levels of protection for the B cell genome during somatic hypermutation
- (2008) Man Liu et al. NATURE
- A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations
- (2008) A Takai et al. ONCOGENE
- APOBEC3G: an intracellular centurion
- (2008) Y.-L. Chiu et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
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- Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney
- (2007) Hong Ming Shen et al. MOLECULAR IMMUNOLOGY
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