Transforming potential and matrix stiffness co-regulate confinement sensitivity of tumor cell migration

Microfabricated collagen tracks facilitate single cell metastatic invasion in 3D

(2013) Casey M. Kraning-Rush et al.   Integrative Biology

A Genetic Strategy for the Dynamic and Graded Control of Cell Mechanics, Motility, and Matrix Remodeling

(2012) Joanna L. MacKay et al.   BIOPHYSICAL JOURNAL

Physical confinement alters tumor cell adhesion and migration phenotypes

(2012) Eric M. Balzer et al.   FASEB JOURNAL

Direct inhibition of myosin II effectively blocks glioma invasion in the presence of multiple motogens

(2012) Sanja Ivkovic et al.   MOLECULAR BIOLOGY OF THE CELL

Independent regulation of tumor cell migration by matrix stiffness and confinement

(2012) A. Pathak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rac signaling in breast cancer: A tale of GEFs and GAPs

(2011) Eva Wertheimer et al.   CELLULAR SIGNALLING

Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness

(2011) Amit Pathak et al.   Integrative Biology

Fabrication of circular microfluidic channels by combining mechanical micromilling and soft lithography

(2011) Mary E. Wilson et al.   LAB ON A CHIP

Cancer Cell Migration: Integrated Roles of Matrix Mechanics and Transforming Potential

(2011) Erin L. Baker et al.   PLoS One

Cancer Cell Stiffness: Integrated Roles of Three-Dimensional Matrix Stiffness and Transforming Potential

(2010) Erin L. Baker et al.   BIOPHYSICAL JOURNAL

A novel role for 14-3-3  in regulating epithelial cell polarity

(2010) C. Ling et al.   GENES & DEVELOPMENT

Identification of the Rac-GEF P-Rex1 as an Essential Mediator of ErbB Signaling in Breast Cancer

(2010) Maria Soledad Sosa et al.   MOLECULAR CELL

A Rac–Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells

(2010) L E Arias-Romero et al.   ONCOGENE

Mechanics, malignancy, and metastasis: The force journey of a tumor cell

(2009) Sanjay Kumar et al.   CANCER AND METASTASIS REVIEWS

14-3-3ζ Cooperates with ErbB2 to Promote Ductal Carcinoma In Situ Progression to Invasive Breast Cancer by Inducing Epithelial-Mesenchymal Transition

(2009) Jing Lu et al.   CANCER CELL

The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells

(2009) T. A. Ulrich et al.   CANCER RESEARCH

Mechanical modes of ‘amoeboid’ cell migration

(2009) Tim Lämmermann et al.   CURRENT OPINION IN CELL BIOLOGY

One-dimensional topography underlies three-dimensional fibrillar cell migration

(2009) Andrew D. Doyle et al.   JOURNAL OF CELL BIOLOGY

Substrate Modulus Directs Neural Stem Cell Behavior

(2008) Krishanu Saha et al.   BIOPHYSICAL JOURNAL

14-3-3  Down-regulates p53 in Mammary Epithelial Cells and Confers Luminal Filling

(2008) C. G. Danes et al.   CANCER RESEARCH