Cisplatin-mediated c-myc overexpression and cytochrome c (cyt c) release result in the up-regulation of the death receptors DR4 and DR5 and the activation of caspase 3 and caspase 9, likely responsible for the TRAIL-sensitizing effect of cisplatin

RNAi-based Knockdown of Multidrug Resistance-associated Protein 1 is Sufficient to Reverse Multidrug Resistance of Human Lung Cells

(2015) Shu-Li Shao et al.   Asian Pacific Journal of Cancer Prevention

Clitocine targets Mcl-1 to induce drug-resistant human cancer cell apoptosis in vitro and tumor growth inhibition in vivo

(2014) Jian-guo Sun et al.   APOPTOSIS

Posttranscriptional regulation of c-Myc expression in adult murine HSCs during homeostasis and interferon- -induced stress response

(2014) A. Ehninger et al.   BLOOD

MYC through miR-17-92 Suppresses Specific Target Genes to Maintain Survival, Autonomous Proliferation, and a Neoplastic State

(2014) Yulin Li et al.   CANCER CELL

Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis

(2014) Arianna Sabò et al.   NATURE

Sorafenib Sensitizes Solid Tumors to Apo2L/TRAIL and Apo2L/TRAIL Receptor Agonist Antibodies by the Jak2-Stat3-Mcl1 Axis

(2013) Junaid Abdulghani et al.   PLoS One

Dovitinib sensitizes hepatocellular carcinoma cells to TRAIL and tigatuzumab, a novel anti-DR5 antibody, through SHP-1-dependent inhibition of STAT3

(2012) Kuen-Feng Chen et al.   BIOCHEMICAL PHARMACOLOGY

MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors

(2012) Wajana L. Labisso et al.   CELL CYCLE

Suppression of multidrug resistance by treatment with TRAIL in human ovarian and breast cancer cells with high level of c-Myc

(2011) Dae-Young Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Functional Polymorphisms in FAS/FASL System Contribute to the Risk of Occurrence but not Progression of Gastric Cardiac Adenocarcinoma

(2011) Weimin Zhang et al.   HEPATO-GASTROENTEROLOGY

Age-Specific Trends in Incidence of Noncardia Gastric Cancer in US Adults

(2010) William F. Anderson   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

TRAIL sensitize MDR cells to MDR-related drugs by down-regulation of P-glycoprotein through inhibition of DNA-PKcs/Akt/GSK-3β pathway and activation of caspases

(2010) Suk-Bin Seo et al.   Molecular Cancer

The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway

(2008) S Wang   ONCOGENE