Increased lanosterol turnover: a metabolic burden for daunorubicin-resistant leukemia cells

Rewired Metabolism in Drug-resistant Leukemia Cells

(2015) Claudia Stäubert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Establishment and characterization of a bladder cancer cell line with enhanced doxorubicin resistance by mevalonate pathway activation

(2015) Annemarie Greife et al.   TUMOR BIOLOGY

Hydroxycarboxylic acid receptors are essential for breast cancer cells to control their lipid/fatty acid metabolism

(2015) Claudia Stäubert et al.   Oncotarget

The E3 Ubiquitin Ligase MARCH6 Degrades Squalene Monooxygenase and Affects 3-Hydroxy-3-Methyl-Glutaryl Coenzyme A Reductase and the Cholesterol Synthesis Pathway

(2014) N. Zelcer et al.   MOLECULAR AND CELLULAR BIOLOGY

Statin use in primary inflammatory breast cancer: a cohort study

(2013) T M Brewer et al.   BRITISH JOURNAL OF CANCER

Tracking the clonal origin of lethal prostate cancer

(2013) Michael C. Haffner et al.   JOURNAL OF CLINICAL INVESTIGATION

Combined Inhibitory Effects of Celecoxib and Fluvastatin on the Growth of Human Hepatocellular Carcinoma Xenografts in Nude Mice

(2013) J Gao et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Sterol homeostasis requires regulated degradation of squalene monooxygenase by the ubiquitin ligase Doa10/Teb4

(2013) Ombretta Foresti et al.   eLife

Triparanol suppresses human tumor growth in vitro and in vivo

(2012) Xinyu Bi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The endogenous regulator 24(S),25-epoxycholesterol inhibits cholesterol synthesis at DHCR24 (Seladin-1)

(2011) Eser J. Zerenturk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease

(2011) L Lim et al.   CELL DEATH AND DIFFERENTIATION

Cholesterol-Dependent Degradation of Squalene Monooxygenase, a Control Point in Cholesterol Synthesis beyond HMG-CoA Reductase

(2011) Saloni Gill et al.   Cell Metabolism

Terbinafine inhibits oral squamous cell carcinoma growth through anti-cancer cell proliferation and anti-angiogenesis

(2011) Ming-Hsien Chien et al.   MOLECULAR CARCINOGENESIS

Atorvastatin Induces Apoptosis In Vitro and Slows Growth of Tumor Xenografts but Not Polyp Formation in Min Mice

(2010) Emina H. Huang et al.   DIGESTIVE DISEASES AND SCIENCES

In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS

(2010) Jose Castro-Perez et al.   JOURNAL OF LIPID RESEARCH

Mitochondrial Cholesterol Contributes to Chemotherapy Resistance in Hepatocellular Carcinoma

(2008) J. Montero et al.   CANCER RESEARCH

24(S),25-Epoxycholesterol: A messenger for cholesterol homeostasis

(2008) Andrew J. Brown   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain

(2007) Nan Wang et al.   FASEB JOURNAL