Rewired Metabolism in Drug-resistant Leukemia Cells

Prognostic impact of expression and methylation status of DENN/MADD domain-containing protein 2D in gastric cancer

(2014) Mitsuro Kanda et al.   Gastric Cancer

Base Preferences in Non-Templated Nucleotide Incorporation by MMLV-Derived Reverse Transcriptases

(2014) Pawel Zajac et al.   PLoS One

Substrate specificity of human carnitine acetyltransferase: Implications for fatty acid and branched-chain amino acid metabolism

(2013) Sara Violante et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

P-glycoprotein ABCB1: a major player in drug handling by mammals

(2013) Piet Borst et al.   JOURNAL OF CLINICAL INVESTIGATION

Tracking the clonal origin of lethal prostate cancer

(2013) Michael C. Haffner et al.   JOURNAL OF CLINICAL INVESTIGATION

MCJ/DnaJC15, an Endogenous Mitochondrial Repressor of the Respiratory Chain That Controls Metabolic Alterations

(2013) K. M. Hatle et al.   MOLECULAR AND CELLULAR BIOLOGY

Metabolic targets for cancer therapy

(2013) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting cellular metabolism to improve cancer therapeutics

(2013) Y Zhao et al.   Cell Death & Disease

Mechanisms and insights into drug resistance in cancer

(2013) Hiba Zahreddine et al.   Frontiers in Pharmacology

Dose intensification of daunorubicin and cytarabine during treatment of adult acute lymphoblastic leukemia

(2012) Wendy Stock et al.   CANCER

Molecular Pathways: Regulation and Therapeutic Implications of Multidrug Resistance

(2012) K. G. Chen et al.   CLINICAL CANCER RESEARCH

Targeting MDR in breast and lung cancer: Discriminating its potential importance from the failure of drug resistance reversal studies

(2012) Laleh Amiri-Kordestani et al.   DRUG RESISTANCE UPDATES

Suppression of non-small cell lung cancer proliferation and tumorigenicity by DENND2D

(2012) Bing Ling et al.   LUNG CANCER

Clonal evolution in cancer

(2012) Mel Greaves et al.   NATURE

Highly multiplexed and strand-specific single-cell RNA 5′ end sequencing

(2012) Saiful Islam et al.   Nature Protocols

Targeting tumor cell metabolism with statins

(2012) J W Clendening et al.   ONCOGENE

Selection of Metastatic Breast Cancer Cells Based on Adaptability of Their Metabolic State

(2012) Balraj Singh et al.   PLoS One

Metabolic reprogramming in cancer: Unraveling the role of glutamine in tumorigenesis

(2012) Dania Daye et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cancer metabolism: current perspectives and future directions

(2012) C Muñoz-Pinedo et al.   Cell Death & Disease

Characterization of the single-cell transcriptional landscape by highly multiplex RNA-seq

(2011) S. Islam et al.   GENOME RESEARCH

Clonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapse

(2011) Emmanuelle Clappier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Identifying Static and Kinetic Lipid Phenotypes by High Resolution UPLC–MS: Unraveling Diet-Induced Changes in Lipid Homeostasis by Coupling Metabolomics and Fluxomics

(2011) Jose M. Castro-Perez et al.   JOURNAL OF PROTEOME RESEARCH

Pyruvate carboxylase is required for glutamine-independent growth of tumor cells

(2011) T. Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutamine Synthetase Is a Genetic Determinant of Cell Type–Specific Glutamine Independence in Breast Epithelia

(2011) Hsiu-Ni Kung et al.   PLoS Genetics

Inverse relationship between leukaemic cell burden and plasma concentrations of daunorubicin in patients with acute myeloid leukaemia

(2010) Alex Bogason et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS

(2010) Jose Castro-Perez et al.   JOURNAL OF LIPID RESEARCH

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Fenofibrate Simultaneously Induces Hepatic Fatty Acid Oxidation, Synthesis, and Elongation in Mice

(2009) Maaike H. Oosterveer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Prediction of relapse in paediatric pre-B acute lymphoblastic leukaemia using a three-gene risk index

(2008) Katrin Hoffmann et al.   BRITISH JOURNAL OF HAEMATOLOGY

Transient ectopic expression as a method to detect genes conferring drug resistance

(2008) James Witham et al.   INTERNATIONAL JOURNAL OF CANCER

PPAR  agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition

(2008) D. Panigrahy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic Analysis of the Clonal Origins of Relapsed Acute Lymphoblastic Leukemia

(2008) C. G. Mullighan et al.   SCIENCE

Multiple Ionization Mass Spectrometry Strategy Used To Reveal the Complexity of Metabolomics

(2007) Anders Nordström et al.   ANALYTICAL CHEMISTRY