Soluble biglycan induces the production of ICAM-1 and MCP-1 in human aortic valve interstitial cells through TLR2/4 and the ERK1/2 pathway

Notch1 Promotes the Pro-Osteogenic Response of Human Aortic Valve Interstitial Cells via Modulation of ERK1/2 and Nuclear Factor-κB Activation

(2013) Qingchun Zeng et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Biglycan Induces the Expression of Osteogenic Factors in Human Aortic Valve Interstitial Cells via Toll-Like Receptor-2

(2012) Rui Song et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Small leucine-rich proteoglycans orchestrate receptor crosstalk during inflammation

(2012) Kristin Moreth et al.   CELL CYCLE

Cross-Talk Between the Toll-Like Receptor 4 and Notch1 Pathways Augments the Inflammatory Response in the Interstitial Cells of Stenotic Human Aortic Valves

(2012) Q. Zeng et al.   CIRCULATION

Small leucine-rich proteoglycans, at the crossroad of cancer growth and inflammation

(2012) Liliana Schaefer et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways

(2012) Shurong Huang et al.   JOURNAL OF LIPID RESEARCH

Molecular Imaging Insights Into Early Inflammatory Stages of Arterial and Aortic Valve Calcification

(2011) Sophie E.P. New et al.   CIRCULATION RESEARCH

Toll-like receptors

(2011) Eva Marie Y. Moresco et al.   CURRENT BIOLOGY

The Proteoglycan Biglycan Enhances Antigen-Specific T Cell Activation Potentially via MyD88 and TRIF Pathways and Triggers Autoimmune Perimyocarditis

(2011) Z. V. Popovic et al.   JOURNAL OF IMMUNOLOGY

Increased Biglycan in Aortic Valve Stenosis Leads to the Overexpression of Phospholipid Transfer Protein via Toll-Like Receptor 2

(2010) Habib Derbali et al.   AMERICAN JOURNAL OF PATHOLOGY

Differential proteoglycan and hyaluronan distribution in calcified aortic valves

(2010) Elizabeth H. Stephens et al.   CARDIOVASCULAR PATHOLOGY

The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis

(2010) Kristin Moreth et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanical Strain and the Aortic Valve: Influence on Fibroblasts, Extracellular Matrix, and Potential Stenosis

(2009) Sven Lehmann et al.   ANNALS OF THORACIC SURGERY

Nonrheumatic calcific aortic stenosis: an overview from basic science to pharmacological prevention☆

(2009) Alessandro Parolari et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

Biglycan, a Danger Signal That Activates the NLRP3 Inflammasome via Toll-like and P2X Receptors

(2009) Andrea Babelova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microfilaments Facilitate TLR4-Mediated ICAM-1 Expression in Human Aortic Valve Interstitial Cells

(2009) Yong Song et al.   JOURNAL OF SURGICAL RESEARCH

Pro-Osteogenic Phenotype of Human Aortic Valve Interstitial Cells Is Associated With Higher Levels of Toll-Like Receptors 2 and 4 and Enhanced Expression of Bone Morphogenetic Protein 2

(2009) Xiaoping Yang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Chemokines in Vascular Dysfunction and Remodeling

(2008) Andreas Schober   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Biological Functions of the Small Leucine-rich Proteoglycans: From Genetics to Signal Transduction

(2008) Liliana Schaefer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of functional Toll-like receptors 2 and 4 in human aortic valve interstitial cells: potential roles in aortic valve inflammation and stenosis

(2007) Xianzhong Meng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY